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1.
Arch Bronconeumol ; 44(10): 567-70, 2008 Oct.
Article in Spanish | MEDLINE | ID: mdl-19006637

ABSTRACT

We report the case of a Spanish nonimmunosuppressed patient who was a chronic alcoholic and who developed chronic cavitary pulmonary histoplasmosis. He had been living in Venezuela until 10 years ago. The diagnosis was established when Histoplasma capsulatum was cultured from bronchoscopy samples. The patient was treated with itraconazole and progressed favorably until cure. This case suggests that histoplasmosis can reactivate years after exposure, even when significant immunodeficiency is not present. In the absence of another immunosuppressive factor, alcoholism may have played a role in the development of the condition.


Subject(s)
Histoplasmosis/diagnosis , Lung Diseases, Fungal/diagnosis , Chronic Disease , Endemic Diseases , Histoplasmosis/epidemiology , Humans , Immunocompetence , Male , Middle Aged , Venezuela/epidemiology
2.
Arch. bronconeumol. (Ed. impr.) ; 44(10): 567-570, oct. 2008. ilus
Article in Es | IBECS | ID: ibc-68462

ABSTRACT

Se presenta el caso de un paciente español, no inmunodeprimido,con alcoholismo crónico e histoplasmosis pulmonarcavitaria, crónica, que había residido 10 años antes en Venezuela.El diagnóstico se estableció por cultivo de Histoplasmacapsulatum en muestras de broncoscopia y el tratamientoconsistió en itraconazol, con buena evolución y curación.Este caso apoya la posibilidad de que la histoplasmosis puedareactivarse años después de la exposición y sin que hayainmunodepresión clínicamente importante. Se plantea que,en ausencia de otro factor inmunodepresor, el alcoholismopodría haber desempeñado algún papel en el desarrollo delcuadro


We report the case of a Spanish non immunosuppressed patient who was a chronic alcoholic and who developed chronic cavitary pulmonary histoplasmosis. He had beenliving in Venezuela until 10 years ago. The diagnosis wasestablished when Histoplasma capsulatum was cultured frombronchoscopy samples. The patient was treated withitraconazole and progressed favorably until cure. This casesuggests that histoplasmosis can reactivate years afterexposure, even when significant immunodeficiency is notpresent. In the absence of another immunosuppressivefactor, alcoholism may have played a role in the development of the condition


Subject(s)
Humans , Male , Middle Aged , Histoplasmosis/complications , Histoplasmosis/diagnosis , Radiography, Thoracic/methods , Tomography, Emission-Computed/methods , Histoplasmosis/immunology , Alcoholism/complications , Alcoholism/diagnosis , Histoplasma/isolation & purification , Histoplasma/pathogenicity , Signs and Symptoms , Radiography, Thoracic/trends , Radiography, Thoracic
3.
Enferm. emerg ; 10(3): 130-133, jul.-sept. 2008. tab
Article in Spanish | IBECS | ID: ibc-90757

ABSTRACT

Objetivo: Evaluar la adecuación del aislamiento y la respuesta microbiológica al tratamiento en pacientes con tuberculosis (TB).Métodos: Determinaciones: 1. Adecuación del aislamiento: hospitalario (sospecha diagnóstica y aislamiento desde la admisión en la planta de hospitalización) o domiciliario (diagnóstico y tratamiento tras el alta en urgencias y aislamiento en el domicilio 15 días). 2. Influencia del tratamiento en el estado bacteriológico del esputo. Resultados: 1. De 100 pacientes consecutivos con TB, 50 tenían baciloscopia +, 37 de ellos tenían aislamiento correcto (28 hospitalario, 9 domiciliario). En los 13 restantes el aislamiento fue incorrecto,3 domiciliario (dos alta sin aislamiento y retraso diagnóstico de 7 y 10 días, otro con aislamiento 10días) y 10 ingresados (retraso de 1-14 días, media 4.5; en 5 retraso de un día y en los 5 restantes retraso de 3 a 14 días). 2. De 50 pacientes con baciloscopia + en 14 se realizó control microbiológicoal mes del inicio del tratamiento (todos baciloscopia +, 10 cultivo +). En 25 con control al 2º mes, 8baciloscopia +, 7 Cultivo +.Conclusiones: 1. Se ha objetivado que en el 13% de los pacientes con TB no se realizó el aislamiento correctamente. 2. En pacientes con TB bacilífera, tras uno o dos meses de tratamiento existe un número importante con baciloscopia y cultivo +. Se deben controlar la política de aislamiento y la respuesta microbiológica al tratamiento por la influencia que pueden tener en la transmisión de la TB (AU)


Aim: To know 1º. The respiratory isolation policy, 2º. The effect of treatment on the sputum bacteriologic status in patients with tuberculosis (TB).Methods: 1. Description of isolation policies. We defined correct isolation in hospital as diagnosis suspicion and isolation on admission and duration no less than 15 days and correct domiciliary isolation as diagnosis in emergency room with recommendation of treatment and stay at home at least 15days. 2. Follow-up of sputum status after treatment. Results: 1. 100 consecutive patients, sputum smear + in 50, 37 with correct isolation (28 in hospital and 9 domiciliary). In 13 with incorrect isolation, 3 were outpatients (2 without diagnosis neither isolation and delay in diagnosis of 7 and 10 days and another with domiciliary isolation of 10 days). In10 inpatients the diagnosis delay was 1 to 14 days (mean 4.5). 2. Fifty positive smear patients were followed-up for bacteriology controls. First month control on 14 showed positive smear for all and positive culture for 10 of them. Second month control was performed on 25, 8 of them were smear positive and 7 culture positive. Conclusions: 1. In 13% of patients with TB we did not perform the isolation correctly. 2. There was a high rate of positives smear and culture after one and two months of treatment within TB patients with initial positive smear. We must control isolation policy and bacteriologic response to treatment because of the influence that can have in TB transmission (AU)


Subject(s)
Humans , Sputum/microbiology , Tuberculosis/microbiology , Mycobacterium tuberculosis/isolation & purification , Patient Isolation , Disease Transmission, Infectious/prevention & control
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