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Am J Trop Med Hyg ; 106(2): 574-577, 2021 11 22.
Article in English | MEDLINE | ID: mdl-34814109

ABSTRACT

Chaetomium sp. is a mold, member of the phylum Ascomycota. Clinical disease in humans is rare, particularly in children, for which only five cases have been reported. We report a 7-months-old female patient with a diagnosis of visceral heterotaxy syndrome who was admitted to a private center in Mexico. After two episodes of focal myoclonic seizure, a brain magnetic resonance imaging (MRI) revealed a right porencephalic cyst and a right frontal abscess with ventriculitis. Seventy-two hours after temporal abscesses drainage procedure, the culture showed a rapidly growing pale white fungal colony. Sequencing of internal transcribed spacer (ITS) and D1/D2 led to the identification of Chaetomium strumarium. Although Chaetomium sp. is a rare fungal infection in humans, clinicians should consider it as a plausible etiologic agent that can form brain abscess.


Subject(s)
Cerebral Phaeohyphomycosis/diagnostic imaging , Chaetomium/pathogenicity , Heterotaxy Syndrome/complications , Mycoses/diagnostic imaging , Antifungal Agents/therapeutic use , Brain/diagnostic imaging , Chaetomium/genetics , Female , Heterotaxy Syndrome/microbiology , Humans , Infant , Magnetic Resonance Imaging , Mexico , Mycoses/drug therapy
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