ABSTRACT
No disponible
Subject(s)
Male , Adult , Humans , Myocardial Ischemia/complications , Myotonic Dystrophy/complications , Myocardial Ischemia/diagnosis , Myotonic Dystrophy/diagnosis , Tomography, Emission-Computed, Single-PhotonSubject(s)
HIV Seropositivity/complications , Paranasal Sinus Diseases/complications , Sinusitis/complications , Humans , Immunoglobulin G/immunology , Mycobacterium avium Complex/isolation & purification , Paranasal Sinus Diseases/physiopathology , Sinusitis/microbiology , Sinusitis/physiopathologyABSTRACT
The role of ciprofloxacin and trimethoprim-sulfamethoxazole (TMP-SMZ) was evaluated in empiric treatment of uncomplicated Salmonella enteritis in a comparative, double-blind trial. Patients were randomized to receive ciprofloxacin (500 mg), TMP-SMZ (160/800 mg), or placebo orally twice daily for 5 days. There were 65 evaluatable patients with acute, uncomplicated, culture-confirmed Salmonella enteritis. Duration of diarrhea, abdominal pain, or vomiting and time to defervescence were not significantly different for patients treated with ciprofloxacin, TMP-SMZ, or placebo; there also were no significant differences with respect to full resolution of symptoms for ciprofloxacin versus placebo (point estimate, 0.2 days; 95% confidence interval [CI], -0.5 to 0.9 days) or for TMP-SMZ versus placebo (point estimate, 0.2 days; 95% CI, -1.0 to 0.6 days). The rate of clearance of salmonellae from stools was not significantly different among the groups.
Subject(s)
Ciprofloxacin/therapeutic use , Enteritis/drug therapy , Salmonella Infections/drug therapy , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use , Acute Disease , Adult , Double-Blind Method , Drug Combinations , Feces/microbiology , Female , Humans , Male , Middle AgedABSTRACT
We prospectively evaluated 61 episodes of bacteremia in 54 patients with hepatic cirrhosis, representing 9% of the overall number of bacteremic episodes in adult patients seen in our center during the study period. Spontaneous bacteremia represented 46% of all episodes (virtually always in patients with ascites), followed by the urinary origin (30%). Gram negative organisms were isolated in 71% of episodes. 43% of these were hospital-acquired 25% of patients had spontaneous peritonitis. Among other complications of bacteremia there were shock (28%), renal failure (24%), and disseminated intravascular coagulation (6%). The mortality rate due to sepsis was 28%, that due to complications of cirrhosis by itself was 20%, and that of nonrelated diseases was 8%. Shock and renal failure secondary to bacteremia were independent predictors of a poor prognosis.
Subject(s)
Liver Cirrhosis/complications , Sepsis/epidemiology , Acute Kidney Injury/etiology , Adult , Aged , Cross Infection/epidemiology , Female , Gram-Negative Bacteria/isolation & purification , Gram-Positive Bacteria/isolation & purification , Humans , Liver Cirrhosis/mortality , Male , Middle Aged , Peritonitis/complications , Peritonitis/epidemiology , Prospective Studies , Risk Factors , Sepsis/complications , Sepsis/microbiology , Sepsis/mortality , Shock, Septic/etiology , Shock, Septic/mortalityABSTRACT
A 67-yr-old woman was admitted with dyspnoea, chest and neck pain and swelling of both supraclavicular fossae and the neck. Chest X-ray showed bilateral pleural effusions. Thoracocentesis yielded a milky fluid with a high triglyceride level. Four previously published cases had similar clinical manifestations. The pathophysiology is discussed.
