ABSTRACT
The author considers that the AMES and TNM systems are reliable in determining the prognosis in patients with well differentiated thyroid carcinoma. In low risk patients with tumors less than 2 cm in diameter, total lobectomy and hormonal suppression are sufficient therapy. In other patients, total or subtotal thyroidectomy are advisable to facilitate further control and therapy. Total or subtotal thyroidectomy should always be done in high risk patients. Metastases to the regional lymph nodes are not an important risk factor, but they should always be excised. Radioactive iodine therapy is not useful for low risk patients.
Subject(s)
Thyroid Neoplasms/pathology , Adult , Female , Humans , Male , Middle Aged , Neoplasm Metastasis , Neoplasm Staging , Prognosis , Risk , Thyroid Neoplasms/surgeryABSTRACT
The author reviews the treatment of duodenal ulcer from its beginnings with gastroenterostomy one hundred years ago. He points out that treatment has changed as it was better understood that hypersecretion of acid was an important ulcerogenic factor. The Sippy regime, with diet and alkali to neutralize acid, and the resection and vagotomy were introduced. He discusses some aspects of the history of these therapies in Panama and points out the importance of the introduction of H2 receptors blocker and other drugs still under investigation.