Subject(s)
Breast Neoplasms/chemistry , Carcinoma, Intraductal, Noninfiltrating/chemistry , Receptors, Estrogen/analysis , Tamoxifen/therapeutic use , Adult , Aged , Aged, 80 and over , Breast Neoplasms/drug therapy , Carcinoma, Intraductal, Noninfiltrating/drug therapy , Combined Modality Therapy , Humans , Male , Middle Aged , Receptors, Estrogen/drug effects , Remission Induction , Retrospective StudiesABSTRACT
Se estudio el patron de proteinas con el metodo de electroforesis en gel de poliacrilamida en 24 adenocarcinomas y en 24 muestras de tejido mamario adyacente a las neoplasias.Se observaron diferencias importantes en los patrones proteinicos de ambos tipos de tejidos. Parece existir cierta correlacion entre algunos patrones de proteinas y la presencia de actividad tumoral temprana ulterior a la mastectomia
Subject(s)
Humans , Female , Breast Neoplasms , Proteins , Albumins , Electrophoresis, Polyacrylamide GelABSTRACT
Protein pattern was studied using discontinuous polyacrylamide gel electrophoresis in 53 adenocarcinomas, 13 fibroadenomas and 66 samples of mammary tissue adjacent to neoplasias. Important differences were found in patterns of both types of neoplasias, the same as between malignant tissues and non neoplastic adjacent tissues. There seems to be a certain correlation between some protein pattern and NOS and lobular histological types. It was also observed that some protein patterns were more frequent in neoplasias with metastasis to axillary nodes and vascular invasion. On the other hand, there seems to be important correlation between some protein patterns and the presence of early tumoral activity after mastectomy that is present even in the absence of positive axillary nodes at the moment of surgery.
Subject(s)
Adenocarcinoma/analysis , Adenofibroma/analysis , Breast Neoplasms/analysis , Neoplasm Proteins/analysis , Electrophoresis, Polyacrylamide Gel , Female , Humans , Lymphatic Metastasis , Neoplasm Recurrence, Local , Neoplasm StagingABSTRACT
PIP: 2 patients aged 31 and 35, multiparous, and wearer of a Dalkon Shield IUD for a period of 3-5 years, were hospitalized for bilateral tubo-ovarian actinomicosis. Both patients were surgically treated, and in both cases there were necrotic materials. An adequate diagnosis of actinomycosis would be incomplete without careful citological examinations of cervico-vaginal exudations. It is also important to stress that any type of IUD should not be worn for longer than 2 years. The article presents a review of the published literature on the subject.^ieng
