ABSTRACT
Introducción: la patología vascular cerebral tiene un enormeimpacto en la vida de las personas. Ocasiona grandes pérdidasdesde el punto de vista físico, psicológico y social. La recuperaciónde la enfermedad cerebrovascular aguda (ECVA) esun fenómeno complejo que hasta la fecha ha sido escasamenteinvestigado desde la perspectiva del paciente. El objetivo deeste trabajo es conocer qué significa la recuperación para laspersonas que recientemente han sufrido un ictus.Metodología: estudio cualitativo en el que se desarrollaronentrevistas en profundidad a 12 pacientes afectados de ictus duranteel primer mes de su recuperación. Se entrevistó en dosocasiones a cada participante, una en el hospital y otra en sudomicilio. Las entrevistas fueron grabadas y transcritas en sutotalidad. Se alcanzó la saturación de los datos. El texto generadofue analizado mediante análisis del discurso.Resultados y conclusiones: el significado de la recuperaciónpara los pacientes es un objetivo, en el que la pérdida y la recuperaciónde lo perdido son lo importante, y un proceso dondela esperanza, la incertidumbre y la búsqueda de evidenciasde mejoría conforman las categorías. Describieron que paraellos recuperarse significa llegar a estar como estaban antesdel ictus o en el caso de que esto no fuera posible, por lo menos,recuperar para valerse. A pesar de que reconocen que sufuturo es incierto, conservan la esperanza de que con tiempoy esfuerzo conseguirán recuperarse.Los resultados obtenidos son coherentes con la bibliografíarevisada. La comprensión de lo que recuperarse significa paralas personas con ictus es esencial para el planteamiento de objetivosy el desarrollo de planes de cuidados individualizados (AU)
Introduction: Brain vascular pathology has an enormous impacton the patients life. It leads to great physical, psychologicaland social losses. Recovery from acute cerebrovasculardisease (ACVD) is a complex phenomenon which up untilrecently had been scarcely studied from the patients perspective.The objective of this study is to understand what recoverymeans to patients who have recently suffered an ictus.Methodology: qualitative study in which 12 ictus patientswere interviewed in-depth within the first month of recovery.Each participant was interviewed twice, once in the hospitaland once in their home. Each interview was recorded andtranscribed in its entirety. Data saturation was reached. Thegenerated text was analyzed using discourse analysis.Results and conclusions: to patients, recovery encompassestwo dimensions: recovery as an objective, in which loss andrecovery of what has been lost are the most important aspects;and recovery as a process, where hope, uncertainty and thesearch for evidence of improvement constitute the categories.They determined that recovery means returning to their previousstate, before the ictus, or, in the case of that not beingpossible, at least recovering enough to be self-sufficient.Although they acknowledge that their future is uncertain, theyremain hopeful that with time and effort they will achieve recovery.The results obtained are coherent with reviewed literature.Understanding what recovery means to ictus patients is essentialto determine objectives and to develop individualizad care plans (AU)
Subject(s)
Humans , Male , Female , Aged , Stroke/rehabilitation , Recovery of Function , Nursing Care/methods , Uncertainty , Patient SatisfactionABSTRACT
Although there is considerable evidence implicating apolipoprotein E (ApoE) epsilon4 in the development of the Alzheimer's disease (AD), additional factors are also known to be involved. Thus, an association has been described between C267T polymorphism of the 5-hydroxytryptamine 6 receptor (5-HT(6)) receptor gene and AD. This case-control study analyzes the ApoE and 5-HT(6) receptor polymorphisms in 173 cases and 102 age and sex matched controls from Araba and Bizkaia (The Basque Country, Spain). The analysis of ApoE showed the frequencies of epsilon4 allele to be significantly higher in AD patients (0.292) than in the controls (0.083). When 5-HT(6) receptor polymorphism was analyzed, a greater frequency of 267C allele was observed in AD patients than in controls, though the difference was not statistically significant. Likewise regarding ApoE epsilon4 status, no statistically significant difference was observed. In conclusion, the association of ApoE epsilon4 to AD in a sample of patients from the Basque Country is confirmed, though the association to C267T polymorphism of the 5-HT(6) receptor has not been observed.
