ABSTRACT
Resumen La infección por el virus de la hepatitis C (VHC) se distribuye en todo el mundo, frecuentemente se convierte en hepatitis crónica, cirrosis y hepatocarcinoma. El genoma del VHC es una molécula de ARN monocatenario, de polaridad positiva, de aproximadamente 9.6 kb de longitud. Esta revisión resume el conocimiento actual y los avances recientes en la investigación de la biología molecular del VHC.
Abstract Infection with hepatitis C virus (HCV), which is distributed worldwide, often becomes in chronic hepatitis, cirrhosis and hepatocellular carcinoma. The HCV genome is a single-stranded RNA molecule of positive polarity approximately 9.6 kb in length. This review summarizes the current knowledge of recent advances in the investigation of the molecular biology of HCV.
ABSTRACT
Since the identification of hepatitis C in 1989, it has been studied extensively. In addition to its hepatotropic; have extrahepatic effects that are directly related to extrahepatic replication with high affinity to lymphoid tissues. As a result of that characteristics, autoimmune manifestations or a widespread immune stimulation, hematological, endocrine, dermatological, Ophtalmic, salival and other miscellaneous problems can be presented in affected patients.
Subject(s)
Hepatitis C/complications , Endocrine System Diseases/etiology , Hematologic Diseases/etiology , Humans , Skin Diseases/etiologyABSTRACT
Desde su identificación en 1989 el virus de la Hepatitis C ha sido muy estudiado, encontrando que además de su acción hepatotrópica presenta efectos extrahepáticos que tienen una relación directa a su gran afinidad linfotrópica que genera manifestaciones de naturaleza autoinmune ó de extensa estimulación inmunitaria que dan manifestaciones hematológicas, endocrinas, renales, dermatológicas, oculares y otras diversas que se describen en esta revisión.
Since the identification of hepatitis C in 1989, it has been studied extensively. In addition to its hepatotropic; have extrahepatic effects that are directly related to extrahepatic replication with high affinity to lymphoid tissues. As a result of that characteristics, autoimmune manifestations or a wide spread immune stimulation, hematological, endocrine, dermatological, Ophtalmic, salival and other miscellaneous problems can be presented in affected patients.
Subject(s)
Autoimmune Diseases , Hepatitis CABSTRACT
The pregnancy supposes a deep change in the human physiology. Such changes can entail the appearance of diseases that secondarily affect the liver, like the hipermesis gravidica, HELLP syndrome, the cholestasis of pregnancy and the acute hepatic steatosis of the pregnancy. Within the acquired diseases, viral hepatitis are the first cause of jaundice in the pregnant. Hepatitis E can display a particularly aggressive course and also the Herpes simple virus. In relation to hepatitis C during the pregnancy, their presence does not affect the pregnancy, childbirth or perinatal health of the mother and Newborn. The main concern of the heath workers is to diminish the risk of transmission of the disease from the mother to newborn.
