ABSTRACT
Flamenco is a popular art, symbol of the culture of southern Spain, has a growing number of fans both from this country and from the rest of the world. This paper tried to find out if flamenco can be a determinant motivational element when choosing a destination and if there is a specific flamenco tourist who tries to travel to symbolic flamenco places. The results show evidence of the existence of three motivational dimensions directly related to flamenco: flamenco experience, flamenco brand, flamenco pretext. Also, a so-called 'musical dimension' was observed, where the motivation to participate in musical experiences in general prevailed. Based on these motivational dimensions, three types of flamenco tourists were identified: flamenco lovers, friends of flamenco, and musical attraction. It was found that the group formed by 'flamenco lovers' has a very high sensitivity to all musical variables related to flamenco, being this one, the most numerous group.
ABSTRACT
Adenosine is a nucleoside involved in the pathogenesis of allergic diseases. Its effects are mediated through its binding to G protein-coupled receptors: A1, A2a, A2b and A3. The receptors differ in the type of G protein they recruit, in the effect on adenylyl cyclase (AC) activity and the downstream signaling pathway triggered. Adenosine can produce both an enhancement and an inhibition of mast cell degranulation, indicating that adenosine effects on these receptors is controversial and remains to be clarified. Depending on the study model, A1, A2b, and A3 receptors have shown anti- or pro-inflammatory activity. However, most studies reported an anti-inflammatory activity of A2a receptor. The precise knowledge of the adenosine mechanism of action may allow to develop more efficient therapies for allergic diseases by using selective agonist and antagonist against specific receptor subtypes.
