ABSTRACT
El síndrome de Contarini es una presentación infrecuente de derrame pleural bilateral en la cual el líquido pleural en cada hemitórax presenta diferentes características, y puede explicarse por diferentes causas. Hay escasa literatura al respecto, por lo que presentamos un caso de derrame pleural bilateral que sería compatible con dicho síndrome (AU)
Contarinis syndrome is an infrequent presentation of bilateral pleural effusion, in which the pleural fluid in each hemithorax has different characteristics and can be explained by different causes. There is limited literature on this syndrome, so we present a case of bilateral pleural effusion that would be compatible with this syndrome (AU)
Subject(s)
Humans , Male , Middle Aged , Pleural Effusion/diagnostic imaging , Pleural Effusion/therapy , Tomography, X-Ray Computed , Thoracentesis , SyndromeABSTRACT
Pulmonary fibrosis can be caused by external agents, including certain drugs. For some time now, tumor necrosis factor antagonists such as etanercept have been used to treat certain autoimmune diseases. Fibrosis caused by medication responds to withdrawal of the drug and treatment with corticosteroids. Very rarely, fibrosis is irreversible. We present the case of a patient who developed pulmonary fibrosis after initiating treatment with etanercept. The clinical course was fulminant despite withdrawal of the drug and high doses of corticosteroids.
Subject(s)
Immunoglobulin G/adverse effects , Pulmonary Fibrosis/chemically induced , Tumor Necrosis Factor-alpha/antagonists & inhibitors , Adult , Etanercept , Fatal Outcome , Humans , Male , Receptors, Tumor Necrosis FactorABSTRACT
La fibrosis pulmonar es una enfermedad que puede estar causada por agentes externos como determinados fármacos. Desde hace un tiempo se utilizan fármacos antagonistas del factor de necrosis tumoral (TNF) para ciertas enfermedades autoinmunitarias, siendo un ejemplo de estos fármacos el etanercept. Las fibrosis secundarias a medicamentos se caracterizan por la respuesta a la retirada del fármaco y a esteroides. En muy raras ocasiones se produce una fibrosis irreversible. Presentamos el caso de un paciente que desarrolló una fibrosis pulmonar tras iniciar tratamiento con etanercept y que tuvo un curso clínico nefasto a pesar de la retirada del anti-TNF y dosis altas de esteroides
Pulmonary fibrosis can be caused by external agents, including certain drugs. For some time now, tumor necrosis factor antagonists such as etanercept have been used to treat certain autoimmune diseases. Fibrosis caused by medication responds to withdrawal of the drug and treatment with corticosteroids. Very rarely, fibrosis is irreversible. We present the case of a patient who developed pulmonary fibrosis after initiating treatment with etanercept. The clinical course was fulminant despite withdrawal of the drug and high doses of corticosteroids (AU)
