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1.
PLoS One ; 15(7): e0236401, 2020.
Article in English | MEDLINE | ID: mdl-32692779

ABSTRACT

Medical data are often tricky to get mined for patterns even by the generally demonstrated successful modern methodologies of deep learning. This paper puts forward such a medical classification task, where patient registers of two of the categories are sometimes hard to be distinguished because of samples showing characteristics of both labels in turn in several repetitions of the screening procedure. To this end, the current research appoints a pre-processing clustering step (through self-organizing maps) to group the data based on shape similarity and relabel it accordingly. Subsequently, a deep learning approach (a tandem of convolutional and long short-term memory networks) performs the training classification phase on the 'cleaned' samples. The dual methodology was applied for the computational diagnosis of electrooculography tests within spino-cerebral ataxia of type 2. The accuracy obtained for the discrimination into three classes was of 78.24%. The improvement that this duo brings over the deep learner alone does not stem from significantly higher accuracy results when the performance is considered for all classes. The major finding of this combination is that half of the presymptomatic cases were correctly found, in opposition to the single deep model, where this category was sacrificed by the learner in favor of a good accuracy overall. A high accuracy in general is desirable for any medical task, however the correct identification of cases before the symptoms become evident is more important.


Subject(s)
Deep Learning , Electrooculography , Unsupervised Machine Learning , Algorithms , Cluster Analysis , Databases as Topic , Humans , Neural Networks, Computer , Photic Stimulation , Saccades/physiology , Time Factors
2.
Sensors (Basel) ; 20(5)2020 Mar 06.
Article in English | MEDLINE | ID: mdl-32155936

ABSTRACT

Due to the repercussion of falls on both the health and self-sufficiency of older people and on the financial sustainability of healthcare systems, the study of wearable fall detection systems (FDSs) has gained much attention during the last years. The core of a FDS is the algorithm that discriminates falls from conventional Activities of Daily Life (ADLs). This work presents and evaluates a convolutional deep neural network when it is applied to identify fall patterns based on the measurements collected by a transportable tri-axial accelerometer. In contrast with most works in the related literature, the evaluation is performed against a wide set of public data repositories containing the traces obtained from diverse groups of volunteers during the execution of ADLs and mimicked falls. Although the method can yield very good results when it is hyper-parameterized for a certain dataset, the global evaluation with the other repositories highlights the difficulty of extrapolating to other testbeds the network architecture that was configured and optimized for a particular dataset.


Subject(s)
Accidental Falls , Activities of Daily Living , Neural Networks, Computer , Accelerometry , Adolescent , Aged , Aged, 80 and over , Databases as Topic , Female , Humans , Reproducibility of Results , Young Adult
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