A New Therapeutic Application of Platelet-Rich Plasma to Chronic Breast Wounds: A Prospective Observational Study.

The aim of this study was to investigate the usefulness of platelet-rich plasma (PRP) treatment for chronic wounds (CWs) of the breast. A prospective study was performed in 23 patients with CW of the breast who were treated with PRP. The procedure was repeated until the wound was closed completely. The study included patients with a history of breast cancer (n = 8) and patients without cancer (n = 15). The treatment with PRP was successful in all cases and observed in ≤4 weeks in 82.6% (19/23) of patients. The patients without breast cancer showed significantly less time for wound closure than the patients with a history of breast cancer. Moreover, a greater number of PRP treatments were necessary to achieve wound closure in patients undergoing conservative breast treatment. No patients had complications associated with the application of PRP. Conclusions: To the best of our knowledge, this is the first study to reveal that PRP treatment for CWs of the breast is safe, simple, useful and well-tolerated by patients.

A New Management Technique for Symptomatic Haematomas Following Therapeutic Vacuum-Assisted Biopsy.

The aim of this study was to investigate the efficacy of the vacuum-assisted biopsy (VAB) system in evacuating symptomatic haematomas after VAB excision of benign breast lesions. We retrospectively analysed the data of eight patients with symptomatic and large haematomas who were treated with VAB evacuation between 10 and 14 days after VAB excision. Only one case underwent the procedure 24 h after VAB excision, due to the patient reporting intense pain, which was relieved after application of the technique, even though it had to be done twice. This new clinical application of the VAB system for evacuating symptomatic breast haematomas was successful in all the cases in the present study. No technique-related complications were observed. Conclusions: To the best of our knowledge, this is the first study to reveal that VAB evacuation of symptomatic haematomas is safe, effective, quick and well-tolerated by patients.

Neumoencéfalo a tensión secundario a ventilación mecánica no invasiva en paciente con traumatismo craneoencefálico grave / Tension pneumocephalus secondary to non-invasive mechanical ventilation in a patient with severe traumatic brain injury

La presencia de aire dentro de la cavidad intracraneal es una entidad rara que se conoce con el nombre de neumoencéfalo y en la mayoría de los casos no presenta repercusión clínica salvo cuando ocasiona un aumento de la presión intracraneal que puede llegar a producir un deterioro del nivel de conciencia, coma e incluso la muerte. Presentamos un caso, poco frecuente, de un varón joven sin antecedentes personales de interés que ingresa en una unidad de cuidados intensivos para vigilancia tras un accidente de tráfico con traumatismo craneoencefálico asintomático y con tomografía computarizada craneal de ingreso «sin hallazgos significativos». Durante su estancia en la unidad de cuidados intensivos se aplica presión positiva en la vía aérea con ventilación mecánica no invasiva que genera entrada de aire en la cavidad intracraneal (neumoencéfalo) que condiciona deterioro neurológico importante con necesidad de cirugía urgente

The presence of air inside intracranial cavity is a rare entity known as pneumocephalus and in most cases doesn??t present any clinical repercussion except in case of elevated intracranial pressure that can lead to a decreasing level of consciousness, coma and even death. We present a rare case of a young male, without medical precedents of interest, hospitalized in an intensive care unit for vigilance after a traffic accident with asymptomatic crane encephalic trauma and cranial computerized tomography without meaningful findings. During the intensive care unit stay positive pressure is applied in airway with non-invasive mechanical ventilation that produces air entrance in cranial cavity (pneumocephalus) causing neurological deterioration and necessity of urgent surgery

Tension pneumocephalus secondary to non-invasive mechanical ventilation in a patient with severe traumatic brain injury. / Neumoencéfalo a tensión secundario a ventilación mecánica no invasiva en paciente con traumatismo craneoencefálico grave.

The presence of air inside intracranial cavity is a rare entity known as pneumocephalus and in most cases doesnt present any clinical repercussion except in case of elevated intracranial pressure that can lead to a decreasing level of consciousness, coma and even death. We present a rare case of a young male, without medical precedents of interest, hospitalized in an intensive care unit for vigilance after a traffic accident with asymptomatic crane encephalic trauma and cranial computerized tomography without meaningful findings. During the intensive care unit stay positive pressure is applied in airway with non-invasive mechanical ventilation that produces air entrance in cranial cavity (pneumocephalus) causing neurological deterioration and necessity of urgent surgery.