Subject(s)
Methionine , Protein Sorting Signals , Humans , Alleles , Racemethionine , HLA-B Antigens/geneticsABSTRACT
Sequence and expression analysis of the HLA-DRB1*10:38 allele.
Subject(s)
HLA-DRB1 Chains , Humans , HLA-DRB1 Chains/genetics , Base Sequence , AllelesABSTRACT
Genomic full-length characterization of the HLA-DQB1*03:25:01 allele.
Subject(s)
HLA-DQ Antigens , Humans , HLA-DQ Antigens/genetics , Alleles , HLA-DQ beta-Chains/genetics , HaplotypesABSTRACT
Characterization of two novel HLA class I null alleles.
Subject(s)
HLA-B Antigens , Nucleotides , Humans , Alleles , Mutation , HLA-B Antigens/genetics , High-Throughput Nucleotide SequencingABSTRACT
The novel HLA-DQB1*04:02:01:16Q allele showing a point mutation in the intron 3.
Subject(s)
Point Mutation , Alleles , HLA-DQ beta-Chains/genetics , Humans , IntronsABSTRACT
Six novel HLA alleles were characterized in the Spanish population.
Subject(s)
Alleles , Gene Frequency , HLA-DP beta-Chains/genetics , HumansABSTRACT
Characterization of the novel HLA-C allele, HLA-C*07:1000.
Subject(s)
HLA-C Antigens , Recombination, Genetic , Alleles , Genes, MHC Class I , HLA-C Antigens/genetics , HumansABSTRACT
Five new HLA class I alleles were characterized by next-generation sequencing.
Subject(s)
HLA-A Antigens , High-Throughput Nucleotide Sequencing , Alleles , HLA-A Antigens/genetics , HumansABSTRACT
Two new HLA-DRB3 alleles were characterized, DRB3*02:151 and DRB3*03:48.
Subject(s)
HLA-DR Antigens , Alleles , Base Sequence , HLA-DR Antigens/genetics , HLA-DRB1 Chains/genetics , HLA-DRB3 Chains/genetics , HumansSubject(s)
Genomics , HLA-C Antigens , Alleles , HLA-C Antigens/genetics , Humans , Recombination, Genetic , Sequence Analysis, DNAABSTRACT
Characterization of three new HLA class I alleles, B*50:73, C*08:218 and C*15:229.
Subject(s)
Genes, MHC Class I , HLA-B Antigens , Alleles , HLA-B Antigens/genetics , HLA-C Antigens/genetics , HumansABSTRACT
We identified a new HLA-C allele, HLA-C*03:03:01:32, with a splice site mutation in intron 5.
Subject(s)
Alternative Splicing , HLA-C Antigens , Alleles , Genes, MHC Class I , Humans , Introns/geneticsABSTRACT
Four new HLA alleles characterized by NGS, B*40:455, C*03:521, C*03:04:81 and DQB1*03:431.
Subject(s)
HLA-A Antigens , HLA-C Antigens , Alleles , Gene Frequency , HLA-A Antigens/genetics , HLA-B Antigens/genetics , HLA-C Antigens/genetics , HLA-DQ beta-Chains/genetics , HLA-DRB1 Chains/genetics , Haplotypes , HumansABSTRACT
Twelve new HLA class I alleles were characterized in the Spanish population.
Subject(s)
Genes, MHC Class I , Alleles , Gene Frequency , Humans , SpainABSTRACT
A new HLA null allele, DRB1*15:176N, was characterized in a Spanish volunteer bone marrow donor.
Subject(s)
Bone Marrow/chemistry , Exons/genetics , HLA-DRB1 Chains/genetics , Polymorphism, Single Nucleotide , Sequence Analysis, DNA/methods , Tissue Donors , Alleles , Amino Acid Sequence , Amino Acid Substitution , Base Sequence , Haplotypes , Humans , Sequence Homology , SpainABSTRACT
Two new HLA-C alleles, HLA-C*05:01:01:17 and -C*16:152 were detected and characterized.
Subject(s)
Alleles , HLA-C Antigens/genetics , Base Sequence , Exons/genetics , Histocompatibility Testing , HumansABSTRACT
Description of HLA-B*56:01:01:05S with a point mutation at the acceptor splicing site within intron 4.
