[Helicobacter pylori: 6-day triple therapy in duodenal ulcer]. / Helicobacter pylori: triple terapia de 6 días en el ulcus duodenal.

OBJECTIVES: To find the effectiveness of short-term eradication treatment of Helicobacter pylori in the duodenal ulcer. DESIGN: Intervention study, open controlled, randomised with parallel groups. SETTING: Three Health Centres in the city of Valencia. PATIENTS: Patients with a duodenal ulcer diagnosis and a Helicobacter pylori infection who attended the Primary Care physician. INTERVENTION: The study group (48 patients) was treated for six days with the triple therapy: Amoxycillin, Clarithromycin and Omeprazole. The control group (40 patients) was treated with Omeprazole for six weeks. MEASUREMENTS AND MAIN RESULTS: The observance period lasted a year, after which the Elisa test was conducted. Eradication was successful for 65% of those treated with the triple therapy, but for only 30% of those treated with monotherapy. The consumption of medication for the ulcer during the year of observance was almost three times greater in the group treated with monotherapy than in the triple-therapy group. CONCLUSIONS: Eradicative triple therapy was shown to be more effective and efficient than monotherapy. It is feasible to use it in Primary Care. Eradicative triple therapy is not advisable within six days: a longer treatment period should be employed with this recommendable therapy.

[Biliary drainage in the diagnosis of microlithiasis. Value in acute idiopathic pancreatitis and in persistent pain in the right hypochondrium]. / El drenaje biliar en el diagnóstico de la microlitiasis. Valor en la pancreatitis aguda idiopática y en el dolor en hipocondrio derecho persistente.

We present a microscopic study of bills obtained via biliary drainage from 33 patients with the diagnosis of acute idiopathic pancreatitis, 33 subjects with pain in the epigastrium and U.Q. with the suspicion of biliary origin, but not revealed by means of routine techniques, and 14 patients with confirmed biliary lithiasis. Duodenal intubation under radiological control was used in all cases, with the administration of 2 UI/kg of CCK IV, in order to study bile A and B under polarized light microscopy. We found cholesterol crystals in 12 cases (36.3%) of acute idiopathic pancreatitis, 5 cases (15.1%) of right hypocondrial pain, and 14 (100%) of biliary lithiasis. Calcium bilirubinate granules were obtained in 15 cases (45.4%) of acute idiopathic pancreatitis, 8 cases (24.4%) of pain in the right hypocondrium and 7 (50%) of biliary lithiasis. We detected giardia in one case of acute idiopathic pancreatitis and an other with pain in the right U.Q. In conclusion, biliary drainage reveals its diagnostic importance in the study of biliary pathology in patients diagnosed of acute idiopathic pancreatitis as well as in cases of chronic right U.Q. al pain suggestive of biliary pathology.