ABSTRACT
Objetivo: Evaluar si existe asociación entre obesidad y mortalidad en la Unidad de Cuidados Intensivos (UCI) en pacientes adultos que reciben ventilación mecánica invasiva. Diseño: Revisión sistemática con metaanálisis. Ámbito: UCI. Fuente de datos: Se realizó una búsqueda en las bases de datos MEDLINE, Cochrane Library, CINAHL y Global Health sin restricción de lenguaje, hasta el 21 de febrero del año 2017. Selección de estudios: Se incluyeron estudios que informaron mortalidad en UCI en pacientes obesos versus no obesos que recibieron VMI. Variables principal: Mortalidad en UCI. Resultados: Se hallaron 2.163 artículos, de los cuales se incluyeron 14 estudios. No se encontraron diferencias estadísticamente significativas entre los pacientes obesos y no obesos respecto a la variable mortalidad en UCI (odds ratio: 0,94; intervalo de confianza del 95%: 0,81-1,10; p=0,45). Conclusión: No se halló relación entre el subgrupo de pacientes adultos obesos que reciben VMI y la variable mortalidad en UCI
Objective: To evaluate if there is an association between obesity and mortality in the Intensive Care Unit (ICU) in adult patients receiving invasive mechanical ventilation. Design: Systematic review with meta-analysis. Scope: ICU. Data source: A search was made in MEDLINE, Cochrane Library, CINAHL and Global Health databases without language restriction, until February 21, 2017. Selection of studies: Studies that reported mortality in the ICU in obese versus non-obese patients who received IMV were included. Main variables: Mortality in the ICU. Results: 2163 articles were found, of which 14 studies were included. No statistically significant differences were found between obese and non-obese patients with respect to the variable mortality in the ICU (OR: 0.94, 95% CI: 0.81-1.10, P=.45). Conclusion: No relationship was found between the subgroup of obese adult patients receiving IMV and the mortality variable in the ICU
Subject(s)
Humans , Adult , Obesity/mortality , Respiration, Artificial/instrumentation , Critical Care/methods , Intensive Care Units , Risk Factors , Body Mass Index , 28599ABSTRACT
OBJECTIVE: To evaluate if there is an association between obesity and mortality in the Intensive Care Unit (ICU) in adult patients receiving invasive mechanical ventilation. DESIGN: Systematic review with meta-analysis. SCOPE: ICU. DATA SOURCE: A search was made in MEDLINE, Cochrane Library, CINAHL and Global Health databases without language restriction, until February 21, 2017. SELECTION OF STUDIES: Studies that reported mortality in the ICU in obese versus non-obese patients who received IMV were included. MAIN VARIABLES: Mortality in the ICU. RESULTS: 2163 articles were found, of which 14 studies were included. No statistically significant differences were found between obese and non-obese patients with respect to the variable mortality in the ICU (OR: 0.94, 95% CI: 0.81-1.10, P=.45). CONCLUSION: No relationship was found between the subgroup of obese adult patients receiving IMV and the mortality variable in the ICU.
Subject(s)
Hospital Mortality , Intensive Care Units , Obesity/mortality , Respiration, Artificial/mortality , Body Mass Index , Confidence Intervals , Humans , Length of Stay , Odds Ratio , Prospective Studies , Publication Bias , Retrospective StudiesABSTRACT
Objetivo: Conocer la prevalencia y las características epidemiológicas de los pacientes infectados por el virus de la inmunodeficiencia humana que requirieron ventilación mecánica invasiva más de 12 horas para tratar la insuficiencia respiratoria aguda en la Unidad de Cuidados Intensivos de un Hospital General de Agudos. Asimismo, se realizó un análisis comparativo entre los pacientes con el virus de la inmunodeficiencia humana y aquellos sin el virus. Materiales y Métodos: Estudio descriptivo, prospectivo y longitudinal llevado a cabo entre el 1 de agosto de 2012 y el 31 de julio de 2014. Se incluyeron adultos con ventilación mecánica invasiva por más de 12 horas debido a insuficiencia respiratoria aguda. Se realizó un análisis multivariado de regresión logística para identificar la asociación entre muerte en la Unidad de Cuidados Intensivos y virus de la inmunodeficiencia humana. Resultados: Ingresaron 344 pacientes en la Unidad, el 46,80% requirió ventilación mecánica invasiva por insuficiencia respiratoria aguda, con una prevalencia del virus de la inmunodeficiencia humana del 12,42%. Los pacientes infectados tenían una media de la edad de 39.42 ± 11.58 vs. 49.37 ± 20.54. En un análisis multivariado, se observó que los pacientes infectados corrían un mayor de riesgo de morir en la Unidad de Cuidados Intensivos que los no infectados (OR: 5,125; IC95% 1,725-15,226; p = 0,003). Conclusión: Los pacientes con el virus de la inmunodeficiencia humana que recibieron ventilación mecánica invasiva más de 12 horas para tratar la insuficiencia respiratoria aguda tuvieron un riesgo cinco veces más alto de morir en la Unidad de Cuidados Intensivos que los no infectados. (AU)
Objective: To know the prevalence and epidemiological characteristics of patients infected with human immunodeficiency virus requiring invasive mechanical ventilation for more than 12 hours as a treatment for acute respiratory failure at the Intensive Care Unit of a General Acute Care Hospital in Buenos Aires City. A comparative analysis was also performed between subjects with human immunodeficiency virus and those not infected. Materials and Methods: Descriptive, prospective and longitudinal study conducted between August 1st, 2012 and July 31st, 2014. Adults with invasive mechanical ventilation for more than 12 hours due to acute respiratory failure were included. A multivariate logistic regression analysis was performed to identify the association between mortality in the Intensive Care Unit and human immunodeficiency virus. Results: A total of 344 patients were admitted to the Intensive Care Unit, 46.80% of them required invasive mechanical ventilation for acute respiratory failure, with a prevalence of human immunodeficiency virus of 12.42%. The average age of infected patients was 39.42 ± 11.58 vs. 49.37 ± 20.54. In a multivariate analysis it was observed that patients with human immunodeficiency virus had more risk of death in the Intensive Care Unit than those not infected (OR: 5.12%, CI95% 1.72-15.22; P=0.003). Conclusion: The risk of death of subjects with human immunodeficiency virus who received invasive mechanical ventilation for more than 12 hours as a treatment for acute respiratory failure was five-fold higher than that of those uninfected patients.(AU)
