[Multicentre study of infection incidence in knee prosthesis]. / Estudio multicéntrico sobre la incidencia de infección en prótesis de rodilla.

OBJECTIVE: To determine the incidence of surgical site infection in knee prosthesis surgical procedure for a follow-up period of one year in twelve hospitals in Madrid region. MATERIAL AND METHOD: A prospective study was carried out from January to December 2009 using a national surveillance system called Indicadores Clínicos de Mejora Continua de Calidad. Primary and revision knee joint replacements in patients operated on in the previous year were included. Criteria used to define surgical site infection and patient risk index categories were those established by the Centers for Disease Control and Prevention and National Nosocomial Infections Surveillance. The incidence rates were worked out crude and adjusted by hazard ratio. RESULTS: 2,088 knee prosthesis procedures were analyzed. The overall incidence of surgical site infection was 2.1%. Sixty-five percent of the infections were organ/space. Sixty percent of the infections were identified in the early postoperative period. Of all surgical site infections, 41.9% were microbiologically confirmed. Antibiotic prophylaxis was implemented correctly in 63.3% of the cases. The most important cause of inappropriate prophylaxis was an unsuitable duration in 85.7% of the cases. The presurgical preparation was carried out correctly in 50.3% of surgical operations. The incidence of knee arthroplasty infection was twice as high as in the National Healthcare Safety Network and similar to national rates. DISCUSSION: In this study, the incidence of infection was within the range of infection rates in other published European studies. Surveillance and control strategies of health care for associated infections allow us to assess trends and the impact of preventive measures.

Estudio multicéntrico sobre la incidencia de infección en prótesis de rodilla / Multicentre study of infection incidence in knee prosthesis

Objetivo. Determinar la incidencia de infección de localización quirúrgica en el procedimiento prótesis de rodilla, durante un año de seguimiento en 12 hospitales madrileños. Material y método. Estudio prospectivo de enero a diciembre de 2009, utilizando el programa Indicadores Clínicos de Mejora Continua de Calidad. Se incluyeron prótesis de rodilla primarias y de revisión intervenidas el año previo. Se utilizaron criterios de infección de localización quirúrgica y categorías por índice de riesgo de los Centros para el Control y Prevención de Enfermedades y del National Nosocomial Infections Surveillance. Se calcularon tasas crudas y ajustadas por índice de riesgo. Resultados. Se analizaron 2.088 procedimientos quirúrgicos de prótesis de rodilla. La tasa global de infección de localización quirúrgica fue del 2,1%. El 65% de las infecciones fueron de órgano/espacio. El 60% de las infecciones se identificaron precozmente. Se obtuvo confirmación microbiológica en el 41,9% de los casos. La profilaxis quirúrgica fue adecuada en el 63,3%, siendo la principal causa de inadecuación su duración en el 85,7%. La preparación prequirúrgica fue correcta en el 50,3% de los pacientes. La tasa de infección en artroplastias de rodilla fue dos veces superior a la esperada según el National Healthcare Safety Network y similares a las tasas nacionales. Discusión. La tasa de infección de nuestro estudio se encuentra dentro del rango de las tasas de infección descritas en otros estudios europeos ya publicados. Las estrategias de vigilancia y control de las infecciones asociadas a la asistencia sanitaria permiten evaluar tendencias y el impacto de las medidas de prevención (AU)

Objective. To determine the incidence of surgical site infection in knee prosthesis surgical procedure for a follow-up period of one year in twelve hospitals in Madrid region. Material and method. A prospective study was carried out from January to December 2009 using a national surveillance system called Indicadores Clínicos de Mejora Continua de Calidad. Primary and revision knee joint replacements in patients operated on in the previous year were included. Criteria used to define surgical site infection and patient risk index categories were those established by the Centers for Disease Control and Prevention and National Nosocomial Infections Surveillance. The incidence rates were worked out crude and adjusted by hazard ratio. Results. 2,088 knee prosthesis procedures were analyzed. The overall incidence of surgical site infection was 2.1%. Sixty-five percent of the infections were organ/space. Sixty percent of the infections were identified in the early postoperative period. Of all surgical site infections, 41.9% were microbiologically confirmed. Antibiotic prophylaxis was implemented correctly in 63.3% of the cases. The most important cause of inappropriate prophylaxis was an unsuitable duration in 85.7% of the cases. The presurgical preparation was carried out correctly in 50.3% of surgical operations. The incidence of knee arthroplasty infection was twice as high as in the National Healthcare Safety Network and similar to national rates. Discussion. In this study, the incidence of infection was within the range of infection rates in other published European studies. Surveillance and control strategies of health care for associated infections allow us to assess trends and the impact of preventive measures (AU)

Influenza vaccination coverage among hospital personnel over three consecutive vaccination campaigns (2001-2002 to 2003-2004).

This study was carried out to assess influenza vaccination coverage among hospital personnel and the impact of health promotion campaigns, within the hospital, designed to increase vaccination coverage over three consecutive vaccination campaigns (2001-2002 to 2003-2004). The health promotion tool used in the 2001-2002 and 2002-2003 were informative posters distributed throughout the hospital. In the 2003-2004 season, the recommendation was also published in the internal bulletin and Web site of the hospital. In addition, a physician and a nurse from the Department of Preventive Medicine visited all departments offering vaccination in the work place. The overall vaccination coverage in the 2001-2002 campaign was 16% with coverage of 11.5% in nurses and 15% in physicians. In the 2002-2003 and 2003-2004 campaigns the overall vaccination coverage was 21% and 40%, respectively (p<0.01). Staff physicians and resident physicians reached 60 and 42% coverage rates in the 2003-2004 campaign, but coverage in nurses and nursing assistant remained around 30% (p<0.01). In summary, influenza vaccination coverage among hospital based healthcare personnel increased significantly during the last three seasons, however, it still remains low despite active attempts at promoting influenza vaccination.

Seroprevalence of varicella antibodies in healthcare workers and health sciences students. Reliability of self-reported history of varicella.

The objective of this study was to assess the seroprevalence of varicella antibodies in healthcare workers and students of healthcare professions and to determine the validity of the self-reported varicella history for detecting susceptible subjects. Personnel of a general hospital and students were recruited and a 5 mL blood sample was obtained from all participants. A case report form, including previous self-reported history of varicella, was completed. A total of 91 healthcare workers (mean age, 30.6 years; S.D., 4.0; range, 23-40) and 92 students (mean age, 19.8 years; S.D., 2.5; range, 18-25) were recruited. The prevalence of varicella antibodies was 91.2% in healthcare workers and 92.1% in students. Overall, the sensitivity, specificity, positive and negative predictive values of a self-reported history of varicella were 68.4%, 66.7%, 95.4% and 17.2%, respectively. The preferred approach in these groups at risk of varicella will be to undergo serologic testing before immunization in those with negative or unknown history of varicella.

Gestión de residuos biosanitarios y citotóxicos en un centro hospitalario / Management of bio-sanitary and cytotoxic wastes at a hospital centre

Los residuos sanitarios generados diariamente, van en aumento y la innovación en las actividades hospitalarias han traído consigo un gran incremento del volumen de desechos clínicos. A una pequeña fracción de éstos, se le atribuyen riesgos asociados a la salud pública y precisarán una gestión diferenciada. El interés por la correcta gestión de estos residuos es creciente y, sin embargo, hay dificultad en la aplicación del sistema de gestión y en el cumplimiento del marco legal. El plan de gestión de residuos es una herramienta para promover una adecuada gestión de residuos en los centros sanitarios. Los profesionales sanitarios y no sanitarios deben ser partícipes, del mismo modo que la información y formación es clave en nuestro trabajo diario, para garantizar un entorno seguro y en mejores condiciones técnicas e higiénicas (AU)

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[Hepatitis B prevention and risk of HIV infection in children injured by discarded needles and/or syringes]. / Prevención de hepatitis B y riesgo de infección por VIH en niños accidentados con agujas y/o jeringuillas abandonadas.

OBJECTIVES: Main aim: to study the application of mixed prophylaxis against Hepatitis B viral infection (HB) in children injured by discarded needles and/or syringes. Secondary aim: to find in the group under study the incidence of HIV infection caused by these accidents. DESCRIPTION: Descriptive study. SETTING: 12 de octubre University Hospital, Madrid. PATIENTS: Children injured by discarded needles and/or syringes and referred to the Preventive Medicine Service between May 1988 and April 1995 (7 years). INTERVENTIONS: 1) Serological study for HB and HIV; 2) application to unprotected children of HB mixed prophylaxis (specific Immunoglobulin--IGHB--plus vaccination) and 3) Post-vaccination serological check-ups for HB and HIV at 6 and 12 months from the incident. MEASUREMENTS AND MAIN RESULTS: 249 children, whose average age was 5.8 +/- 3.37, were seen (158 boys, 63.5% and 91 girls, 36.5%). 189 (75.9% of the total) received a dose of IGHB and 171 (71.8%) completed the HB vaccinations. Post-vaccination serological check-ups covered 144 children (84.2%). 101 children (40.6%) completed the HIV check-ups. No HIV infection was detected. CONCLUSIONS: 1) HB mixed prophylaxis in children without serological protection is adequate for dealing with these incidents. 2) The risk of HIV infection should not be discounted, but is probably very slight. 3) The procedure should be put into practice in PC, with some shortening of HIV follow-up periods, as a measure to improve compliance.

Hepatitis B vaccination in infants of mothers infected with human immunodeficiency virus.

A study was conducted to investigate the immunogenicity of a recombinant DNA hepatitis B vaccine in neonates and children of HIV-infected women. Immunization against hepatitis B consisted of three 10 micrograms doses of the vaccine administered on a 0-, 1- and 6-month schedule. The children were followed up for an average of 11 months. Of the 118 HIV-positive neonates who participated in the study, 95 lost their HIV antibodies during the follow-up period. Most (94.2%) of the latter who completed the study responded to the vaccine. Of the 23 who remained HIV-positive, 17 completed the study and 7 produced hepatitis B antibodies.