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2.
Brain Inj ; 23(5): 403-10, 2009 May.
Article in English | MEDLINE | ID: mdl-19301165

ABSTRACT

PRIMARY OBJECTIVE: To analyse the association between individual initial computerized tomography (CT) scan characteristics and Glasgow Outcome Scale (GOS) and Extended Glasgow Outcome Scale (GOSE) improvement between 6 months and 1 year. METHODS AND PROCEDURES: Two hundred and twenty-four adult patients with severe traumatic brain injury and Glasgow Coma Scale (GCS) score of 8 or less who were admitted to an intensive care unit were studied. GOS and GOSE scores were obtained 6 and 12 months after injury in 203 subjects. Patients were predominantly male (84%) and median age was 35 years. MAIN OUTCOMES AND RESULTS: Traumatic Coma Data Bank (TCDB) CT classification was associated with GOS/GOSE improvement between 6 months and 1 year, with diffuse injury type I, type II and evacuated mass improving more than diffuse injury type III, type IV and non-evacuated mass; for GOS 43/155 (28%) vs 3/48 (6%) (chi(2) = 9.66, p < 0.01) and for GOSE 71/155 (46%) vs 7/48 (15%) (chi(2) = 15.1, p < 0.01). CT individual abnormalities were not associated with GOS/GOSE improvement, with the exception of subarachnoid haemorrhage, which showed a negative association with GOSE improvement (chi(2) = 4.08, p < 0.05). CONCLUSIONS: TCDB CT scan classification and subarachnoid haemorrhage were associated with GOS/GOSE improvement from 6-12 months, but individual CT abnormalities were not associated.


Subject(s)
Brain Injuries/rehabilitation , Glasgow Outcome Scale , Recovery of Function , Adult , Aged , Brain Injuries/diagnostic imaging , Female , Glasgow Coma Scale , Humans , Male , Middle Aged , Prognosis , Prospective Studies , Retrospective Studies , Time Factors , Tomography, X-Ray Computed , Treatment Outcome , Young Adult
3.
Brain Inj ; 21(12): 1225-31, 2007 Nov.
Article in English | MEDLINE | ID: mdl-18236198

ABSTRACT

PRIMARY OBJECTIVE: To assess improvements in Glasgow Outcome Scale (GOS) and GOS extended (GOSE) scores between 6 months and 1 year following severe traumatic brain injury (TBI). METHODS AND PROCEDURES: One studied 214 adult patients with severe TBI with Glasgow Coma Scale (GCS) <9 admitted to Intensive Care Unit (ICU). GOS scores were obtained 6 and 12 months after injury in 195 subjects. Patients were predominantly male (84%) and median age was 35 years. MAIN OUTCOMES AND RESULTS: Outcome (GOS and GOSE at 6 months and 1 year) was better in the high GCS score at admission (6-8) group than in the low score group (3-5). The improvement in GOS scores between 6 months and 1 year was greater in the high GCS score at admission group than in the low score group. At 6 months, 75 patients had died and 120 survived. None died between the 6-12-month assessments; at 12 months, 36% had improved GOS score. CONCLUSIONS: GOS scores improved between 6-12 months after severe TBI in 36% of survivors and it is concluded that the expectancy of improvement is incomplete at 6 months. This improvement was greater in patients with better GCS scores (6-8) at admission than in those with worse GCS scores (3-5).


Subject(s)
Brain Injuries/rehabilitation , Glasgow Coma Scale , Glasgow Outcome Scale , Recovery of Function/physiology , Adult , Brain Injuries/physiopathology , Epidemiologic Methods , Female , Humans , Male , Middle Aged
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