ABSTRACT
INTRODUCTION: This retrospective study was undertaken to evaluate late results of lung cancer surgery in octogenerians. METHODS: All patients 80years old or more who underwent a lung resection for cancer from 2000 to 2010 at Lyon University Hospital were included. No patients were treated with video-assisted surgery. Wedge resections were excluded. RESULTS: Sixty-three patients (42 men, 21 women) were operated. The median age was 82years. Operative mortality was 4.7%. The rate of perioperative complications was 49%. The late survival was 34% at 5years. Five-year survival by nodal involvement was N0, 36%; N1, 29%; N2 20%, P<0.05. Patients with a squamous cell carcinoma (24) had a better long-term survival than patients with an adenocarcinoma (30), 33% and 25% respectively at 5years, P<0.05. The rate of recurrence was 33.9%. CONCLUSIONS: Surgical treatment of lung cancer in selected population of octogenerians is associated with satisfactory early and long-term results. Survival is influenced by nodal involvement and by the pathologic type of the cancer.
Subject(s)
Aged , Lung Neoplasms/surgery , Aged, 80 and over , Female , Geriatric Assessment , Humans , Lung Neoplasms/diagnosis , Lung Neoplasms/epidemiology , Male , Pneumonectomy/methods , Pneumonectomy/mortality , Pneumonectomy/statistics & numerical data , Postoperative Complications/epidemiology , Retrospective Studies , Survival Analysis , Treatment OutcomeABSTRACT
Aim of no residual macroscopic disease has to be the objective of the gynecologist oncologist surgeon. It can require extensive surgical procedures in all the abdomen area. We report 2 rare cases of cytoreductive surgery with iliac vessels resection and use of vascular prosthesis. We discuss the opportunity of this surgery with high morbidity.
Subject(s)
Adenocarcinoma/surgery , Carcinoma, Endometrioid/surgery , Cytoreduction Surgical Procedures , Fallopian Tube Neoplasms/surgery , Iliac Vein/surgery , Adenocarcinoma/pathology , Aged , Blood Vessel Prosthesis , Cytoreduction Surgical Procedures/methods , Fallopian Tube Neoplasms/pathology , Female , Humans , Iliac Vein/pathology , Middle Aged , Neoplasm Recurrence, Local , Neoplasm Staging , Ovarian Neoplasms/pathology , Ovarian Neoplasms/surgery , Venous Thrombosis/pathology , Venous Thrombosis/surgeryABSTRACT
INTRODUCTION: MacLeod syndrome, also known as Swyer-James syndrome, is a rare syndrome characterized by unilateral lung hyperlucency. It is a form of constrictive bronchiolitis which is caused by repeated acute bronchiolitis and/or pulmonary infections during infancy. CASE REPORT: The patient was a 26-year-old man who had had a first left pneumothorax at the age of 21. He smokes tobacco. When he was 1-year-old he had experienced repeated episodes of acute bronchiolitis. At age 26, he suffered from a second left pneumothorax which was wrongly diagnosed as a recurrent drain-resistant pneumothorax. Misdiagnosed, he underwent a chemical pleurodesis during thoracoscopy. As a hyperlucency remained in the left upper part of the lung on chest X-ray, further investigations were undertaken and a diagnosis of MacLeod syndrome was made. CONCLUSIONS: MacLeod syndrome is rare. It can be associated with pneumothorax which can be a source of misdiagnosis and error in the management of these patients. Therefore, the diagnostic criteria and therapeutic indications are reiterated. The probable mechanism of association between pneumothorax and Macleod syndrome is also discussed.
Subject(s)
Lung, Hyperlucent/diagnostic imaging , Pneumothorax/diagnostic imaging , Adult , Bronchiolitis/complications , Chest Pain/etiology , Combined Modality Therapy , Drainage , Dyspnea/etiology , Humans , Lung, Hyperlucent/etiology , Lung, Hyperlucent/surgery , Male , Pleurodesis , Pneumothorax/etiology , Pneumothorax/surgery , Pneumothorax/therapy , Recurrence , Smoking , Tomography, X-Ray ComputedABSTRACT
Except adoption, absolute uterine factor infertility lacks solution in case of motherhood desire. Gestational surrogacy is still not approved in France. Over the last decade, uterus transplantation experimentation made advances. Data from animal research, progress in immunosuppressive treatment and knowledge about pregnancy after transplantation provide a scenario in which a human allotransplantation project can become reality.
Subject(s)
Infertility, Female/etiology , Infertility, Female/surgery , Uterine Diseases/complications , Uterus/transplantation , Animals , Disease Models, Animal , Female , France , Humans , Immunosuppression Therapy , Pregnancy , Surrogate Mothers/legislation & jurisprudenceABSTRACT
INTRODUCTION: A pneumatocele is an air containing cavity, without a wall. It is a rare complication of thoracic trauma. CASE REPORT: The patient was a 46-year-old drug addict, positive for the human immunodeficiency virus. Following a fall in which he fractured the posterior parts of the right 7th and 8th ribs, he developed a subcutaneous fistula and a pneumatocele of the right lower lobe. It did not resolve spontaneously and surgery was undertaken. The pneumatocele and the subcutaneous cavity were drained and the rib fractures were stabilized with Judet struts. CONCLUSIONS: Pneumatocele is a classical but rare complication of thoracic trauma, resulting from a tear of the lung. The differential diagnosis includes localised pneumothorax, an intrathoracic gastric hernia and pneumomediastinum. The usual treatment is surveillance but in this case, surgery was necessary for drainage of the cavities and stabilization of the rib fractures.
