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1.
Pol Tyg Lek ; 51(23-26): 331-3, 1996 Jun.
Article in Polish | MEDLINE | ID: mdl-9273523

ABSTRACT

This studies included 15 children with burns involving 10-55% of the whole body surface, treated at the two surgical departments in Poland. All patients have been given 0.5 mL of a 15% solution of anti-Pseudomonas immunoglobulin in a deep i.m. injections for 3 consecutive days. Immunoglobulin has generally been well tolerated, except short fever attacks. Human anti-Pseudomonas immunoglobulin prepared in the institute of Haematology and Transfusion in Warsaw prevented infections with P. aeruginosa in 12 burned children. There have been no cases of bacteremia produced by P. aeruginosa in 15 treated children with burns. The obtained results indicate efficacy of such therapy in burned children.


Subject(s)
Burns/therapy , Immunization, Passive , Pseudomonas Infections/prevention & control , Adult , Burns/complications , Child , Child, Preschool , Humans , Infant , Injections, Intramuscular , Pseudomonas Infections/etiology
2.
Pol Tyg Lek ; 44(43-45): 924-7, 1989.
Article in Polish | MEDLINE | ID: mdl-2518666

ABSTRACT

Polyvalent Pseudomonas aeruginosa vaccine, prepared at the Institute of Hematology from 10 hospital strains isolated from burn wounds, was administered to 32 children with extensive and deep burns. The vaccine was well tolerated. The vaccine produced a high degree of the immunity against Pseudomonas aeruginosa infection. Agglutinin serum titre increased significantly. Vaccination either prevented or inhibited the infection of burn wounds with Pseudomonas aeruginosa in all immunized children. The symptoms of Pseudomonas aeruginosa infection usually disappeared following one or two vaccinations. Bacteriemia caused by P. aeruginosa was not observed in 31 out of 32 children. In the remaining child transient bacteriemia was noted. No septicemia caused by P. aeruginosa was seen. Due to the high efficiency of the polyvalent P. aeruginosa vaccine all burned children with burns exceeding 10% of the total body surface should by vaccinated to prevent the life-threatening infections with Pseudomonas aeruginosa.


Subject(s)
Bacterial Vaccines/administration & dosage , Burns/complications , Pseudomonas Infections/prevention & control , Pseudomonas aeruginosa/immunology , Wound Infection/prevention & control , Agglutinins/analysis , Antibodies, Bacterial/analysis , Bacterial Vaccines/immunology , Burns/immunology , Child , Child, Preschool , Humans , Poland , Pseudomonas Infections/immunology , Wound Infection/immunology
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