ABSTRACT
19 patients with episodes of transient global amnesia (TGA) were studied, with special reference to the laboratory and instrumental findings (mainly EEG and CT scan). A high proportion of subjects had several risk factors for cerebrovascular disease or CT abnormalities.
Subject(s)
Amnesia/physiopathology , Adult , Aged , Amnesia/complications , Amnesia/diagnostic imaging , Cerebrovascular Disorders/etiology , Electroencephalography , Female , Follow-Up Studies , Heart Valve Diseases/complications , Humans , Male , Middle Aged , Risk , Time Factors , Tomography, X-Ray ComputedABSTRACT
Minimal Record of Disability proposed by the International Federation of Multiple Sclerosis Societies has been evaluated in 148 multiple sclerosis patients living in Genoa, Italy. Statistical percentages on impairment, disability and handicap have been collected also reflecting an image of local health and social services. Critical evaluation of the results led to the following proposals: a) clarify the need of including daily living activities in the evaluation of societal role of MS patients; b) insert evaluation of ability in rising besides bathing and include washing parts of one's body in grooming. Some other minor changes and clarifications are proposed.
Subject(s)
Cross-Cultural Comparison , Disability Evaluation , Multiple Sclerosis/diagnosis , Activities of Daily Living , Adult , Aged , Female , Humans , Italy , Male , Middle Aged , Neurocognitive Disorders/diagnosisSubject(s)
Alcoholism/physiopathology , Epilepsy/physiopathology , Substance Withdrawal Syndrome/physiopathology , Alcoholism/complications , Brain Diseases/etiology , Female , Humans , Liver Diseases, Alcoholic/etiology , Male , Middle Aged , Neural Conduction , Peripheral Nervous System Diseases/etiologyABSTRACT
2 cases of familial paroxysmal kinesigenic choreoathetosis are described. The results of a pharmacological trial with phenobarbital, valproic acid, diazepam, iota-Dopa plus carbidopa, and haloperidol are reported. Phenobarbital is the only effective drug. On this basis the pathophysiological mechanisms of this rare disorder are briefly discussed.
Subject(s)
Athetosis/genetics , Chorea/genetics , Adolescent , Athetosis/diagnosis , Athetosis/drug therapy , Child , Child, Preschool , Chorea/diagnosis , Chorea/drug therapy , Female , Humans , Male , Movement , Phenobarbital/therapeutic useSubject(s)
Carotid Artery Diseases/surgery , Aged , Carotid Artery, Internal , Constriction, Pathologic , Female , Humans , Male , Middle AgedSubject(s)
Carotid Artery Diseases/diagnosis , Ultrasonography , Constriction, Pathologic , Female , Humans , MaleABSTRACT
Neurotic depression covers all forms triggered by exogenous factors, often in conjuction with an underlying personality disposition, and includes reactive, exhaustion and neurotic depression. A feeling of sadness and loss of affection is generally present, together with anxiety provoked by insecurity and apprehension. The complexity of the picture makes treatment of the overall situation difficult with one drug only. For this reason, a series of 25 patients aged 31 to 67 yr with syndromes classifiable as neurotic depression were treated with 2 to 6 daily administrations of an association of 25 nortryptiline and 1 mg trifluoperazine. Analysis of the behaviour of a number of target symptoms showed the effectiveness of the association. There were virtually no side-effects. Success was obtained in the management of anxiety, loss of appetite, depression, irritability, weeping, failure to adapt, and remissiveness, especially in the first week of treatment.