ABSTRACT
Melanoma is a cancer that frequently metastasises to the small bowel, but most cases are asymptomatic and are diagnosed postmortem. Therefore, CT and PET CT cannot detect all lesions and conventional endoscopic study only detects 10-20% of lesions. In this study, we present the case of a 68-year-old patient with a history of cutaneous melanoma and a diagnosis of intestinal melanoma. Thanks to capsule endoscopy, two lesions compatible with cutaneous melanoma metastasis to the small bowel were detected, allowing a much more effective surgical planning. Capsule endoscopy is an innovative technique that improves preoperative diagnosis, as it is able to detect bowel segments that cannot be inspected by conventional endoscopy. It also has a better resolution than conventional CT, improving sensitivity in the detection of lesions.
Subject(s)
Capsule Endoscopy , Intestinal Neoplasms , Melanoma , Skin Neoplasms , Humans , Aged , Melanoma/diagnostic imaging , Melanoma/pathology , Capsule Endoscopy/methods , Skin Neoplasms/pathology , Endoscopy, Gastrointestinal , Intestine, Small/pathology , Intestinal Neoplasms/diagnostic imaging , Intestinal Neoplasms/surgery , Gastrointestinal Hemorrhage/pathologyABSTRACT
No disponible
Subject(s)
Humans , Male , Biliary Tract Diseases/complications , Biliary Tract Diseases/diagnosis , Bile Acids and Salts/analysis , Bile Acids and Salts/deficiency , Delayed Diagnosis/prevention & control , Delayed Diagnosis/trends , Neglected Diseases/complications , Steatorrhea/diet therapy , Steatorrhea/diagnosis , Rare Diseases/complications , Rare Diseases/diagnosis , Rare Diseases/genetics , Fat Soluble Vitamins/analysis , Fat Soluble Vitamins/standardsABSTRACT
Primary infection by cytomegalovirus (CMV) commonly occurs subclinically or manifested by a self-limited mononucleosis-like syndrome in immunocompetent subjects. Severe clinical pictures are uncommon. We present a case of acute myopericarditis and hepatitis in a previously healthy 32-year-old man with primary CMV infection, assessed by serology and positive pp65 antigenemia. He was successfully treated with a course of oral valganciclovir therapy, with an immediate clinical response and normalization of laboratory tests. The literature on simultaneous presentation of CMV pericarditis and hepatitis in immunocompetent hosts, as well as the role of oral valganciclovir in this clinical setting, is reviewed.
