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1.
Rev Med Chir Soc Med Nat Iasi ; 114(4): 1070-6, 2010.
Article in Romanian | MEDLINE | ID: mdl-21500461

ABSTRACT

The Polycystic Ovarian Syndrome is one of the most frequent of the endocrinopathies, affecting in average 8% of the woman's that are in to reproductive age. It was first described by Chereau and Rokitanski, further associated with the amenorrhea encountered in the Stein and Levanthal syndrome, exposed by the Irving F, Stein and Michael Leventhal, in 1935. In many aspects this is a systemic disease also interfering with the process of reproduction. The studies of the genetic factor implication, by relating with the specialty literature, converging with a series of hypotesys launch over the years, show a poligenic affliction or a combination of the environment with the genetics factors. Due to the fact that this syndrome is the most frequently encountered cause of infertility among women's, with a very complex etiopathogeny, the comprehension of it, is most important, because the Polycystic Ovarian Syndrome is a metabolic long term disorder. The study of the genetic act implications is a name part in prophylaxis of the appearance of this syndrome or its complications.


Subject(s)
Polycystic Ovary Syndrome/genetics , Amenorrhea/genetics , Epidermal Growth Factor/genetics , Female , Genetic Markers/genetics , Genetic Predisposition to Disease , Humans , Infertility, Female/genetics , Pedigree , Polycystic Ovary Syndrome/complications , Polycystic Ovary Syndrome/epidemiology , Polycystic Ovary Syndrome/prevention & control , Prevalence , Risk Factors , Romania/epidemiology , Transforming Growth Factors/genetics
2.
Rev Med Chir Soc Med Nat Iasi ; 112(2): 406-10, 2008.
Article in Romanian | MEDLINE | ID: mdl-19295011

ABSTRACT

UNLABELLED: Struma ovarii is a rare tumor in its pure form, but its true incidence is hard to estimate because of all the variation in the diagnostic criteria due to the fact that some authors reported it as within a teratoma and others only in its pure form. In general, it is an asymptomatic tumor, "benign-like" in most of the cases, and the diagnostic is based only on the histopathological findings. MATERIAL AND METHOD: This is a retrospective study of all ovarian tumors treated in our departments over a period of 11 years, from January 1, 1995 to January 1, 2006. RESULTS: All medical records of 644 patients were reviewed, of which 502 patients (77.96%) with unilateral tumors and 142 (22.04%) with bilateral involvement. 879 tumors were removed: 88.39% benign and 11.61% malignant. Struma ovarii was demonstrated in 2 patients. The only complaint in these 2 patients diagnosed and treated in our clinics was pain in the lower abdomen. The clinical examination and ultrasound suggested ovarian tumors, but the diagnosis was made on the histopathological findings. Following surgical treatment (classic or laparoscopic) the postoperative course was excellent, confirming that this approach is the only practical solution.


Subject(s)
Ovarian Neoplasms , Struma Ovarii , Adult , Female , Humans , Middle Aged , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/surgery , Retrospective Studies , Struma Ovarii/diagnosis , Struma Ovarii/surgery , Treatment Outcome
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