ABSTRACT
The genitourinary syndrome of menopause (GSM) and stress urinary incontinence (SUI) are common clinical challenges for women's health and quality of life. The laser treatment and particularly the vaginal erbium laser (VEL) may provide a new non-invasive treatment for both GSM and SUI. However, the estimation of the ultimate results of different laser treatments may be altered by different issues, such as patient selection, concomitant treatments, and long-term effect of vaginal laser thermotherapy. In the present paper, we present the protocol for a large multicenter study on the evaluation of the efficacy and safety of VEL for the treatment of GSM and SUI, the Vaginal Erbium Laser Academy Study (VELAS). This study will evaluate the effects of three laser applications in 1500 postmenopausal women. Subjective and objective symptoms will be evaluated prior to the first laser treatment with follow-up visits after 4 weeks from the last laser application, and subsequently after every 3 months for 1 year. Findings from the VELAS have the potential to affect clinical care practice and health decisions for millions of women world-wide for a non-hormonal treatment for GSM and a non-invasive treatment of SUI.
Subject(s)
Erbium , Female Urogenital Diseases/therapy , Laser Therapy/methods , Menopause , Urinary Incontinence, Stress/therapy , Vagina , Female , Humans , Hyperthermia, Induced/methods , Lasers, Solid-State , Postmenopause , Syndrome , Treatment OutcomeABSTRACT
Os autores estudaram 37 olhos pseudofácicos (37 pacientes) submetidos ao exame de ultra-sonografia ocular devida a baixa acuidade visual associada a diminuiçäo de transparência dos meios. Foram descritos os principais artefatos acústicos criados pela passagem do som através da lente intra-ocular (LIO), bem como suas implicaçöes nos diagnósticos das patologias intra-oculares. O objetivo do trabalho foi alertar os erros mais comuns de interpretaçäo e desse modo, contribuir para a eliminaçäo dos mesmos. Os autores recomendam que os exames ultra-sonográficos dos olhos pseudofácicos sejam realizados evitando-se a transmissäo do som através da LIO
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Endophthalmitis/diagnosis , Vitreous Hemorrhage/diagnosis , Lenses, Intraocular/adverse effects , UltrasonographyABSTRACT
Cinquenta pacientes, submetidos à midríase para investigaçäo clínico-oftalmológica, foram estudados para acompanhamento da reversäo da dilataçäo pupilar com o uso do Cloridrato de Dapiprazole, um alfa-bloqueador existente no mercado internacional. Em aproximadamente 60 por cento do número dos casos, näo foram obtidos resultados significativos na reversäo da midríase medicamentosa com a droga pesquisada. Foram analisadas no trabalho algumas hipóteses que justificariam este resultado
