ABSTRACT
A 25-year-old woman presented to our dermatology unit with progressive diffuse thickening of the both areolas. A skin biopsy was taken from the right areola showing irregular filiform acanthosis with elongation and anastomosis of rete ridges, irregular orthokeratotic hyperkeratosis, pseudocyst formation, and hyperpigmentation of the basal layer. The cause of nevoid hyperkeratosis of the nipple and areola is unknown. Eighty percent of cases occur in women and are often manifested during puberty or pregnancy. The disease may also occur in men receiving hormonal therapy. There is no uniformly effective treatment. Dermatologists, gynecologists, and general practitioners have an important part to play in recognizing this condition that may be underdiagnosed because of lack of awareness.
Subject(s)
Breast Diseases/pathology , Hyperpigmentation/pathology , Keratosis/pathology , Nipples/pathology , Adult , Breast Diseases/diagnosis , Female , Humans , Hyperpigmentation/diagnosis , Keratosis/diagnosisABSTRACT
No disponible
Subject(s)
Humans , Male , Child , Myiasis/pathology , Myiasis/surgery , Myiasis , Erythema/complications , Erythema/diagnosis , Dermis/surgery , Dermis , Hypodermyiasis/parasitology , Wound Infection/parasitology , Wound Infection , Ultrasonography/instrumentation , Ultrasonography/methods , Ultrasonography , Dermis/pathology , Wound Infection/surgery , Hypodermyiasis/complications , Hypodermyiasis/surgery , Hypodermyiasis , Larva/microbiologyABSTRACT
Postradiation sarcomas are rare and highly malignant tumors which may appear as a consequence of radiotherapy. They may originate on bone or soft tissues.We report the case of a patient who developed a malignant fibrous histiocytoma 35 years after radiotherapy for a melanoma on her right leg.
ABSTRACT
No disponible
Subject(s)
Humans , Male , Young Adult , Drug Eruptions/complications , Rifampin/adverse effects , Eczema/chemically induced , Eczema/complications , Eczema/drug therapy , Lupus Erythematosus, Cutaneous/chemically induced , Pemphigoid, Bullous/chemically induced , Pemphigoid, Bullous/complications , Pemphigoid, Bullous/drug therapy , Prednisone/therapeutic use , Antitubercular Agents/adverse effects , Antitubercular Agents/therapeutic use , Fluorescent Antibody Technique/methods , Biopsy , Prurigo/chemically induced , Prurigo/drug therapy , Skin Diseases/chemically induced , Skin Diseases/drug therapy , Exanthema/diagnosis , Exanthema/drug therapySubject(s)
Antitubercular Agents/adverse effects , Drug Eruptions/diagnosis , Isoniazid/adverse effects , Rifampin/adverse effects , Adolescent , Antitubercular Agents/therapeutic use , Drug Eruptions/etiology , Drug Therapy, Combination , Humans , Isoniazid/therapeutic use , Male , Rifampin/therapeutic use , Tuberculosis, Pulmonary/drug therapySubject(s)
Neuroma/diagnosis , Neuroma/pathology , Pacinian Corpuscles/pathology , Pain/etiology , Aged , Fingers , Humans , Male , Neuroma/complicationsABSTRACT
No disponible
Subject(s)
Adult , Female , Humans , Young Adult , Granuloma/complications , Granuloma/diagnosis , Granuloma/therapy , Nontuberculous Mycobacteria , Mycobacterium Infections, Nontuberculous/complications , Mycobacterium Infections, Nontuberculous/diagnosis , Mycobacterium Infections, Nontuberculous/etiology , Granuloma/etiology , Granuloma/prevention & control , Nontuberculous Mycobacteria/growth & development , Nontuberculous Mycobacteria/pathogenicity , Mycobacterium Infections, Nontuberculous/therapyABSTRACT
No disponible
Subject(s)
Adult , Female , Humans , Neurofibromatosis 1/diagnosis , Neurofibromatosis 1/epidemiology , Neurofibromatosis 1/surgery , Skin Neoplasms/diagnosis , Skin Neoplasms/etiology , Skin Neoplasms/therapy , Neurofibromatosis 1/therapy , Skin Neoplasms/epidemiology , Skin Neoplasms/prevention & controlABSTRACT
No disponible
Subject(s)
Female , Humans , Middle Aged , Mycosis Fungoides/complications , Mycosis Fungoides/diagnosis , Mycosis Fungoides/physiopathology , Immunohistochemistry/methods , Immunohistochemistry , Prognosis , Dendritic Cell Sarcoma, Follicular/complications , Dendritic Cell Sarcoma, Follicular/diagnosis , Bone Marrow/pathologyABSTRACT
No disponible
Subject(s)
Adult , Humans , Male , Lichen Planus/diagnosis , Hypertrophy , Neoplasms , Keratosis , Carcinoma, Squamous Cell , Diagnosis, DifferentialABSTRACT
No disponible
Subject(s)
Middle Aged , Female , Humans , Breast/pathology , Skin Pigmentation , Paget's Disease, Mammary/pathology , Breast Neoplasms/pathology , Asymptomatic DiseasesABSTRACT
Cyclosporine A (CyA) is a systemic therapy used to control severe atopic dermatitis (AD) in children, but its use may be associated with serious side effects. Intermittent short-course therapy has been used to minimize these risks without the loss of clinical benefits. We conducted a 20-week study using intermittent short-course CyA therapy in five patients with severe AD and a Scoring Atopic Dermatitis (SCORAD) score >40. The result was a reduction in the cumulative dose of CyA and serum CyA level, which allows for a longer duration of CyA treatment and decreases the risk of relapse in patients with severe AD.
