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[Action of alkaloids from podophyllin on the response of pancreatic beta-cells of the rabbit to tolbutamide]. / Acción de los alcaloides del podifilino sobre la respuesta de la célula beta pancreática de conejos a la tolbutamida.

Gónzalez Larriba, J L; Picaporte, M A; Grande, C; Gasalla Chacón, R; Montero García, J M.

Rev Esp Oncol ; 30(4): 485-90, 1983.

Article in Spanish | MEDLINE | ID: mdl-6400620

ABSTRACT

Some antineoplastic agents alter the microtubular-microfilamentous system involved in insulin release. The authors studied the effect of the podophyllotoxin derivate VM-26 and the epipodophyllotoxin derivative VP-16-213 on the insulin release by the pancreatic beta-cell after tolbutamide stimulation. VP-16-213 produced a slowing and partial inhibition of insulin release, and VM-26 inhibited the late stage of insulin release.

Subject(s)

Etoposide/pharmacology , Insulin/metabolism , Islets of Langerhans/drug effects , Podophyllotoxin/analogs & derivatives , Teniposide/pharmacology , Tolbutamide/pharmacology , Animals , Insulin Secretion , Islets of Langerhans/metabolism , Rabbits

[Acquired sideroblastic anaemia plus chronic lymphocytic leukaemia (author's transl)]. / Anemia sideroblástica adquirida y leucosis linfoide crónica.

Escribano Mora, L; Gasalla Chacon, R; Martínez Guerrero, M L; Ortega Rivas, F; Gómez Villagran, J L; Romero García, C; Sanz Sanz, M.

Sangre (Barc) ; 22(5): 639-45, 1977.

Article in Spanish | MEDLINE | ID: mdl-905941

Subject(s)

Anemia, Sideroblastic/immunology , Leukemia, Lymphoid/immunology , Aged , Bone Marrow/analysis , Bone Marrow/immunology , Chromosomes/analysis , Humans , Immunoglobulins/analysis , Male

[Collagen metabolism and iron deficiency. Preliminary report (author's transl)]. / Metabolismo del colágeno y déficit de hierro. Datos preliminares

Escribano Mora, L; Navajo Galindo, J; Martinez Guerrero, L; de Bustos Benito, J; Gasalla Chacon, R; Ortega Rivas, F; Villar, J M.

Sangre (Barc) ; 21(3): 461-6, 1976.

Article in Spanish | MEDLINE | ID: mdl-184554

Subject(s)

Anemia, Hypochromic/metabolism , Collagen/biosynthesis , Anemia, Hypochromic/enzymology , Connective Tissue/metabolism , Humans , Procollagen-Proline Dioxygenase/metabolism

[Congenital methaemoglobin due to methaemoglobin reductase deficiency (author's transl)]. / Metahemoglobinemia congénita debida a un déficit de metahemoglobín-reductasa a NADH

Gasalla Chacón, R; Gracia, R; del Arco, A; Lledo, G; García de Bustos, J; Romero, C.

Sangre (Barc) ; 21(1): 57-66, 1976.

Article in Spanish | MEDLINE | ID: mdl-1265591

Subject(s)

Cytochrome-B(5) Reductase/deficiency , Methemoglobinemia/enzymology , NADH, NADPH Oxidoreductases/deficiency , Child, Preschool , Female , Humans , Metabolism, Inborn Errors/genetics , Methemoglobinemia/genetics , Pedigree

[Energetics of the erythrocyte conserved at 4-degrees C with ACD, ACD- adenine and CPD (author's transl)]. / Energética del eritrocito conservado a 4-degrees con ACD, ACD-adenina y CPD

Gasalla Chacon, R; Romero Garcia, C; Martin Villar, J; Sanchez Gonzalez, M C.

Sangre (Barc) ; 19(1): 30-40, 1974.

Article in Spanish | MEDLINE | ID: mdl-4840464

Subject(s)

Blood Preservation , Erythrocytes/metabolism , Adenine , Anticoagulants , Citrates , Enzymes/blood , Glucose/metabolism , Humans , Lactates/biosynthesis , Phosphates

[The onset of myelofibrosis with myeloid metaplasia]. / El comienzo de la mielofibrósis con metaplasia mieloide.

Montero García, J M; Juárez Alonso, S; García Lescun, M I; Soleto Sáez, E; Patrón, M; Gasalla Chacón, R.

Rev Clin Esp ; 122(6): 19-24, 1971 Jul 15.

Article in Spanish | MEDLINE | ID: mdl-5120071

Subject(s)

Primary Myelofibrosis/complications , Adult , Biopsy , Bone Marrow Examination , Bone and Bones/pathology , Female , Humans , Liver/pathology , Primary Myelofibrosis/diagnosis , Spleen/pathology , Splenectomy

[Acquired multiple erythrocyte enzyme disorders in sideroblastic anemia]. / Eritro-enzimopatías adquiridas múltiples en la anemia sideroblástica.

Gonzalez Baron, M; Gasalla Chacon, R; Jimenez Herraez, M C; Montero Garcia, J; Duran Perez Navarro, A; Noriega, J.

Sangre (Barc) ; 16(3): 278-83, 1971.

Article in Spanish | MEDLINE | ID: mdl-5120510

Subject(s)

Anemia, Sideroblastic/blood , Erythrocytes/enzymology , Anemia, Sideroblastic/enzymology , Glucosephosphate Dehydrogenase/blood , Glutathione Reductase/blood , Hematopoietic Stem Cells , Heme/biosynthesis , Humans , Porphyrins/analysis , Pyruvate Kinase/blood

[Hemorrhagic thrombocythemia]. / Trombocitemia hemorrágica.

Fernàndez-Chacón, J L; Montero García, J M; Gasalla Chacón, R; Rodríguez Lucio, E; Noriega Marcos, J A.

Rev Clin Esp ; 108(2): 129-36, 1968 Jan 31.

Article in Spanish | MEDLINE | ID: mdl-5754333

Subject(s)

Thrombocythemia, Essential/diagnosis , Aged , Autopsy , Female , Fibrinogen/analysis , Humans , Prothrombin Time , Thrombocythemia, Essential/pathology

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