1.
Zh Nevrol Psikhiatr Im S S Korsakova
; 115(5): 34-40, 2015.
Article
in Russian
| MEDLINE
| ID: mdl-26356158
ABSTRACT
Main mechanisms of action of dopamine receptor agonists, efficacy of their use according to the results of earlier clinical trials and possible side-effects are discussed. The authors present their experience of prescription of rotigotine transdermal system in an open study of 30 patients with Parkinson's disease. The duration of the study was 8 weeks. There was a significant improvement of both motor and nonmotor (pain sensations, sleep, mood). The effective dose for treatment of initial stages was 4-6 mg daily and for the full-blown stage - 6-8 mg daily. The tolerability was good.
Subject(s)
Dopamine Agonists/therapeutic use , Parkinson Disease/drug therapy , Tetrahydronaphthalenes/therapeutic use , Thiophenes/therapeutic use , Administration, Cutaneous , Dopamine Agonists/administration & dosage , Dopamine Agonists/adverse effects , Female , Humans , Male , Motor Activity , Parkinson Disease/physiopathology , Tetrahydronaphthalenes/administration & dosage , Tetrahydronaphthalenes/adverse effects , Thiophenes/administration & dosage , Thiophenes/adverse effects
2.
Zh Nevrol Psikhiatr Im S S Korsakova
; 115(7): 141-145, 2015.
Article
in Russian
| MEDLINE
| ID: mdl-26356527