ABSTRACT
A case of pseudosarcoma of the urinary bladder is described in a woman aged 23. The tumor presenting with symptoms of cystitis arised in the left wall and invaded vesical cavity and pelvis. Histological, histochemical, immunohistochemical and electron microscope studies revealed a fibroblastic and myofibroblastic proliferation with atypias, accompanied by inflammatory infiltrates and rich vascularity. The tumor was furthermore characterized by extensive necrosis, involving the muscularis propria, and infiltrated the perivesical fat. The favourable outcome four years after partial cystectomy suggests the diagnosis of pseudosarcoma. The differential diagnosis and the pathogenesis of this rare lesion is discussed.
Subject(s)
Fibroma/diagnosis , Leiomyosarcoma/diagnosis , Urinary Bladder Neoplasms/diagnosis , Adult , Cystitis/etiology , Diagnosis, Differential , Diagnostic Errors , Female , Fibroma/complications , Fibroma/pathology , Fibroma/surgery , Frozen Sections , Hematuria/etiology , Humans , Leiomyosarcoma/pathology , Lymph Nodes/pathology , Necrosis , Neoplasm Invasiveness , Urinary Bladder/injuries , Urinary Bladder/pathology , Urinary Bladder Neoplasms/pathology , Urinary Bladder Neoplasms/surgeryABSTRACT
Urinary cytology performed in a woman aged 64 revealed an uncommon cell population with malignant features highly suggestive of a lymphoma. Histologic and immunohistochemical investigations of a polypoid endovesical mass surgically resected showed a lymphoma of histiocytes in the lamina propria of the bladder wall. Clinical, operative and pathologic staging demonstrated that the tumor was confined to bladder. The case repeats the typical features of primary vesical lymphoma reported in the literature. The favourable follow up six years after surgery confirms the good prognosis of bladder Iymphoma treated by aggressive therapy.
