Subject(s)
Melanoma/surgery , Skin Neoplasms/surgery , Female , Follow-Up Studies , Humans , Male , Melanoma/diagnosis , Melanoma/pathology , Neoplasm Invasiveness , Neoplasm Metastasis , Neoplasm Recurrence, Local , Neoplasm Staging , Pregnancy , Pregnancy Complications, Neoplastic , Prognosis , Risk Assessment , Skin Neoplasms/diagnosis , Skin Neoplasms/pathologyABSTRACT
INTRODUCTION: Histologically pachydermodactyly results from fibromatosis. Characteristically, the clinical picture occurs almost exclusively in young men. The lesion is localized on the laterodorsal aspect of the proximal phalanges of both hands. CASE REPORT: We observed a 19-year-old man with deformity of the laterodorsal aspect of the first phalanx of the fingers on both hands which had been present for several years. The clinical course and histology of the deformity as well as the lack of any bone lesions led to the diagnosis of pachydermodactyly. COMMENTS: Pachydermodactyl is a rare disease. Our case was comparable to those reported in the literature. A mechanical cause is accepted by most authors.
Subject(s)
Fibroma/pathology , Fingers/abnormalities , Hand Deformities, Acquired , Adult , Hand Deformities, Acquired/pathology , Humans , Male , Sex Factors , Skin/pathologyABSTRACT
Pleomorphic T cell lymphoma of the medium to large cell type expressing CD30 antigen is a most aggressive peripheral T cell lymphoma. Currently, there is no satisfactory treatment available for this neoplasm. We report the case of a woman with prominent skin and bone marrow involvement without detectable lymph node localization. This unusual presentation of disease responded well to polychemotherapy combined with autologous bone marrow transplantation.
