ABSTRACT
A multicenter clinical trial has been fulfilled by 18 Paediatric Hospital Centers in the regions of Piedmont and Aosta Valley, on 139 cases, concerning the use of a new macrolide, miocamycin, in the therapy of various infective diseases, such as upper and lower respiratory tract infections, ear and nose, throat, teeth affections, minor surgery, some contagious diseases. The results of this trial show a good effectiveness of the drug, consisting in a rapid disappearance of the clinical symptoms, a high degree of systemic and gastroenteric tolerability, and very poor side effects.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Bacterial Infections/drug therapy , Leucomycins/therapeutic use , Adolescent , Bronchitis/drug therapy , Child , Child, Preschool , Clinical Trials as Topic , Female , Humans , Infant , Italy , Miocamycin , Otitis/drug therapy , Pneumonia/drug therapy , Respiratory Tract Infections/drug therapyABSTRACT
Three patients with transient hyperphosphatasemia of infancy are described and compared to other 79 cases reported in literature. Etiopathogenesis is discussed and the good prognosis of this condition is emphasized.
Subject(s)
Alkaline Phosphatase/blood , Female , Follow-Up Studies , Humans , Infant , MaleABSTRACT
The authors present three different cases of histiocytosis X: the eosinophilic granuloma, the Hand-Schuller-Christian syndrome and the Letterer-Siwe syndrome. As it appears in the main articles concerning this argument, the Aa. emphasize the common features belonging to the three different forms of histiocytosis: the involvement of the bones and of other tissues. Moreover the prognosis is defined as good in the first case, uncertain in the second case and severe in the third.