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Klin Khir ; (7): 58-61, 2015 Jul.
Article in Ukrainian | MEDLINE | ID: mdl-26591224

ABSTRACT

Modern view of drug therapy in the complex treatment of orthopedic manifestations of osteogenesis imperfecta (OI) was submitted. Developed and tested system of drug correction of structural and functional state of bone tissue (BT) using drugs pamidronovic acid, depending on osteoporosis severity and type of disease. Such therapy is appropriate to apply both independently and in conjunction with surgery to correct deformations of long bones of the lower extremities. Effectiveness and feasibility of the proposed methods of drug therapy was proved, most patients resume features walking and support.


Subject(s)
Bone Density Conservation Agents/therapeutic use , Dietary Supplements , Diphosphonates/therapeutic use , Fractures, Bone/drug therapy , Lower Extremity Deformities, Congenital/drug therapy , Osteogenesis Imperfecta/drug therapy , Osteoporosis/drug therapy , Bone Density/drug effects , Bone and Bones/abnormalities , Bone and Bones/drug effects , Bone and Bones/injuries , Calcium/administration & dosage , Child , Child, Preschool , Female , Fractures, Bone/congenital , Fractures, Bone/diet therapy , Fractures, Bone/surgery , Humans , Infant , Lower Extremity/injuries , Lower Extremity/pathology , Lower Extremity/surgery , Lower Extremity Deformities, Congenital/diet therapy , Lower Extremity Deformities, Congenital/pathology , Lower Extremity Deformities, Congenital/surgery , Male , Orthotic Devices , Osteogenesis Imperfecta/diet therapy , Osteogenesis Imperfecta/pathology , Osteogenesis Imperfecta/surgery , Osteoporosis/congenital , Osteoporosis/diet therapy , Osteoporosis/surgery , Pamidronate , Vitamin D/administration & dosage , Walking
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