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1.
Neurosurg Focus ; 46(1): E9, 2019 01 01.
Article in English | MEDLINE | ID: mdl-30611171

ABSTRACT

OBJECTIVEBoth spontaneous and iatrogenic spondylodiscitis are becoming ever more frequent, yet there are no definite treatment guidelines. For many years the treatment protocol was conservative medical management or surgical debridement with patients immobilized or bedridden for weeks and often resulting in spinal deformity. The eventual development of spinal deformity can be difficult to treat. Over the last few years, the authors have preferred a single-approach instrumented arthrodesis when spondylolysis that evolves in deformity from somatic wedging occurs.METHODSThe authors retrospectively reviewed the clinical, radiological, and surgical records of 11 patients treated over the past 3 years for spondylodiscitis with osteosynthesis.RESULTSOverall, the authors treated 11 patients: 3 cases with tuberculous spondylodiscitis (1 dorsal, 2 lumbar); 6 cases with Staphylococcus aureus spondylodiscitis (1 cervical, 2 dorsal, 2 lumbar, 1 dorsolumbar); 1 spondylodiscitis with postsurgical lumbar deformity; and in 1 dorsolumbar case the germ was not identified. Surgical approaches were chosen according to spinal level: In 8 dorsolumbar cases a posterior osteosynthesis was achieved. In 1 cervical case an anterior approach was performed with autologous bone graft from iliac crest. In 2 thoracolumbar cases a posterolateral costotransversectomy was needed. In 1 lumbosacral case iliac somatic grafting was used. Ten patients received adequate antibiotic treatment with clinical remission, and 1 case is in initial follow-up. No complications due to instrumentation were recorded. Spinal deformity was prevented in 10 cases, whereas preexisting spinal deformity was partially corrected in 1 case. In all cases, arthrodesis achieved vertebral stability.CONCLUSIONSThis study has the limitations of a retrospective review with a limited number of patients. Instrumentation does not appear to hamper healing from infection. Moreover, spinal stabilization, which is assisted by the infectious process even in the absence of bone graft, allows early mobilization. Instrumented osteosynthesis should be preferred for spondylodiscitis with osteolysis and spinal instability because it allows early mobilization and rehabilitation whenever necessary. It prevents spinal deformity and does not hamper healing of infections.


Subject(s)
Discitis/surgery , Lumbar Vertebrae/surgery , Osteolysis/surgery , Thoracic Vertebrae/surgery , Adult , Aged , Bone Transplantation/methods , Debridement/methods , Female , Fracture Fixation, Internal/methods , Humans , Male , Middle Aged , Retrospective Studies , Spinal Fusion/methods
2.
JSLS ; 17(3): 499-502, 2013.
Article in English | MEDLINE | ID: mdl-24018097

ABSTRACT

INTRODUCTION: Emergency surgery for Crohn's disease (CD) is a rare entity, and its indications are scant in the published literature. Emergency laparoscopy for small bowel obstruction has gained wide dissemination with the spread of advanced laparoscopic skills within surgical practice. Therefore, incidental terminal ileitis after exploration might be a more-common finding in the near future, and further studies are needed to better ascertain proper surgical treatment. CASE DESCRIPTION: We report on a case of acute obstruction caused by undiagnosed terminal ileitis associated with CD. DISCUSSION AND CONCLUSION: The patient underwent explorative laparoscopy and subsequent video-assisted ileocecal resection with an optimal outcome.


Subject(s)
Cecal Diseases/surgery , Crohn Disease/surgery , Ileal Diseases/surgery , Intestinal Obstruction/surgery , Laparoscopy/methods , Video-Assisted Surgery , Adult , Emergencies , Female , Humans
3.
ChemSusChem ; 3(7): 834-9, 2010 Jul 19.
Article in English | MEDLINE | ID: mdl-20623724

ABSTRACT

The efficiency of dicarbene palladium(II) complexes and of simple palladium(II) acetate as catalysts for alkyne hydroarylation under liquid-liquid biphasic conditions involving an ionic liquid as the catalyst-containing phase is investigated. The results obtained under these conditions, both in terms of activity and selectivity, are compared with those previously obtained under homogeneous conditions. The catalytic efficiency of the systems is found to be markedly dependent on the nature of the anion of the ionic liquid. Suitable anions are found to significantly improve the catalytic performance in comparison to homogeneous conditions. Preliminary investigations on the recyclability of the system as well as the on advantages of using an acidic ionic liquid are also carried out.


Subject(s)
Alkynes/chemistry , Ionic Liquids/chemistry , Organometallic Compounds/chemistry , Palladium/chemistry , Catalysis , Hydrocarbons, Aromatic/chemistry , Solvents/chemistry
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