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World Neurosurg ; 149: e329-e335, 2021 05.
Article in English | MEDLINE | ID: mdl-33609765

ABSTRACT

BACKGROUND: Although endoscopic endonasal approach (EEA) has been popularized worldwide for pituitary adenoma surgery, in sub-Saharan Africa, neurosurgeons are still only starting their experience with it. This study was designed to assess the early results of EEA for pituitary adenoma from an under-equipped environment, namely, the Department of Neurosurgery of the Teaching Hospital of Yopougon Abidjan and Bouaké in Ivory Coast. METHODS: The data of 56 cases of EEA for pituitary adenoma surgery performed between 2016 and March 2019 at the Teaching Hospital of Yopougon-Abidjan and Bouaké were retrospectively assessed. Pre- and postoperative neuro-ophthalmologic and hormonal status were analyzed. Moreover, the quality of tumor removal, and pre- and postoperative complications were also evaluated. RESULTS: In this study, there were nonfunctional adenomas (20), prolactinoma (18), Cushing disease (9), and acromegaly (3). A reduced visual acuity and/or visual field defect was observed in 49 cases. The mean operation time was 225 ± 94.7 minutes. The tumor removals were complete in 57.14%, subtotal in 35.71%, and partial in 7.14%. These led to a visual improvement in 69.64%. Postoperative complications were cerebrospinal fluid leaks (19.64%), diabetes insipidus (12.50%), visual worsening (7.14%), meningitis (3.57%), and carotid injury (3.57%) that led to death. CONCLUSIONS: This study represents the early surgical experience using EEA for treating pituitary adenoma in an under-equipped environment. Although the postoperative complication rate was relatively high, refinements of local surgeons' technique would lead to a better patient outcome.


Subject(s)
Adenoma/surgery , Neuroendoscopy/methods , Pituitary Neoplasms/surgery , Postoperative Complications/epidemiology , Adenoma/pathology , Adenoma/physiopathology , Adolescent , Adult , Aged , Carotid Artery Injuries/epidemiology , Cerebrospinal Fluid Leak/epidemiology , Cote d'Ivoire , Cranial Nerve Diseases/physiopathology , Diabetes Insipidus/epidemiology , Female , Humans , Male , Meningitis/epidemiology , Middle Aged , Nasal Cavity , Natural Orifice Endoscopic Surgery , Neoplasm, Residual , Operative Time , Pituitary Neoplasms/pathology , Pituitary Neoplasms/physiopathology , Sphenoid Sinus , Treatment Outcome , Vision Disorders/physiopathology , Visual Fields , Young Adult
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