Effects of Different Nursing Modes on Immune Function and Renal Function in Patients with Renal Calculus Undergoing Percutaneous Nephrolithotomy.

BACKGROUND: This study aimed to explore the effects of different nursing modes on immune function and renal function in patients with renal calculus and on percutaneous nephrolithotomy (PCNL). METHODS: A total of 160 patients with kidney stone who were admitted to our hospital from January 2017 to January 2023 were retrospectively selected and equally divided into routine and comprehensive nursing groups. Both groups were treated with percutaneous nephrolithotomy, but the patients in the routine nursing group were treated with usual care, whereas the patients in the comprehensive nursing group were treated with comprehensive nursing. The levels of serum T lymphocyte subsets were detected by flow cytometry, the levels of serum immune indicators and renal function indicators in the two groups were measured and the incidence of postoperative complications and nursing satisfaction were recorded. RESULTS: The levels of serum blood urea nitrogen, creatinine, kidney injury molecule and CD8+ cell subsets in the comprehensive nursing group were lower than those in the routine nursing group (p < 0.05), whereas the CD4+ cell subsets, CD4+:CD8+ ratio, and immunoglobulins (Ig)A, IgG and IgM levels were significantly higher than those in the routine nursing group (p < 0.05). The incidence of postoperative complications in the comprehensive nursing group was 2.50% (2/80), which was significantly lower than that in the routine nursing group (13.75%, 11/80), and the difference was statistically significant (χ2 = 6.782, p = 0.009). Nursing satisfaction in the comprehensive nursing group was 96.25% (77/80), which was significantly higher than that in the routine nursing group (85.00%, 68/80; χ2 = 5.959, p = 0.015). CONCLUSIONS: The comprehensive nursing mode can effectively reduce the influence of PCNL on T cell subsets, immunoglobulin levels in patients with renal calculus, damage to renal function and complications; Can improve patients' satisfaction with nursing; And promote postoperative recovery.

Effects of Different Nursing Modes on Immune Function and Renal Function in Patients with Renal Calculus Undergoing Percutaneous Nephrolithotomy

Background: This study aimed to explore the effects of different nursing modes on immune function and renal function in patients with renal calculus and on percutaneous nephrolithotomy (PCNL). Methods: A total of 160 patients with kidney stone who were admitted to our hospital from January 2017 to January 2023 were retrospectively selected and equally divided into routine and comprehensive nursing groups. Both groups were treated with percutaneous nephrolithotomy, but the patients in the routine nursing group were treated with usual care, whereas the patients in the comprehensive nursing group were treated with comprehensive nursing. The levels of serum T lymphocyte subsets were detected by flow cytometry, the levels of serum immune indicators and renal function indicators in the two groups were measured and the incidence of postoperative complications and nursing satisfaction were recorded. Results: The levels of serum blood urea nitrogen, creatinine, kidney injury molecule and CD8+ cell subsets in the comprehensive nursing group were lower than those in the routine nursing group (p < 0.05), whereas the CD4+ cell subsets, CD4+:CD8+ ratio, and immunoglobulins (Ig)A, IgG and IgM levels were significantly higher than those in the routine nursing group (p < 0.05). The incidence of postoperative complications in the comprehensive nursing group was 2.50% (2/80), which was significantly lower than that in the routine nursing group (13.75%, 11/80), and the difference was statistically significant (χ2 = 6.782, p = 0.009). Nursing satisfaction in the comprehensive nursing group was 96.25% (77/80), which was significantly higher than that in the routine nursing group (85.00%, 68/80; χ2 = 5.959, p = 0.015) (AU)

Environmental Contamination of SARS-CoV-2 Delta VOC by COVID-19 Patients Staying in the Hospital for More Than Two Weeks.

Background: Patients infected with SARS-CoV-2 Delta VOC have a longer course of disease. We detected the air, surfaces, and patient's personal items in the wards of the second hospital of Nanjing during the outbreak of the COVID-19 Delta Variant to identify the environmental contamination, which provides a theoretical basis for the prevention and control of COVID-19 variation beads in the future. Methods: In the cross-sectional study, we collected and analyzed clinical features, demographic and epidemiological data, laboratory and swab test results, and surface and air samples of 144 COVID-19 cases. Results: The time from symptom onset to surface sampling was 25 days (IQR, 21 to 33 days). Positive throat swabs were detected in 52(36.1%) patients, of which only 8(5.6%) patients had N or ORF1a/b genes Ct value <35 on the surface sampling day. Among the 692 environmental surface and air specimens collected from 144 COVID-19 cases, 3 specimens (3/692, 0.4%) related to 5 cases (3.5%, 5/144) were detected positive on RT-PCR. Overall, bedside tables (2/144, 1.4%) were most likely to be contaminated, followed by toilet seats (1/81, 1.2%). Conclusion: The environmental contamination by SARS-CoV-2 Delta VOC-infected cases with disease duration of more than two weeks is limited.

Less Social Support for Patients With COVID-19: Comparison With the Experience of Nurses.

Context: Since December 2019, more than 80,000 patients have been diagnosed with coronavirus disease 2019 (COVID-19) in China. Social support status of COVID-19 patients, especially the impact of social support on their psychological status and quality of life, needs to be addressed with increasing concern. Objectives: In this study, we used social support rating scale (SSRS) to investigate the social support in COVID-19 patients and nurses. Methods: The present study included 186 COVID-19 patients at a Wuhan mobile cabin hospital and 234 nurses at a Wuhan COVID-19 control center. Responses to a mobile phone app-based questionnaire about social support, anxiety, depression, and quality of life were recorded and evaluated. Results: COVID-19 patients scored significantly lower than nurses did on the Social Support Rating Scale (SSRS). Among these patients, 33.9% had anxiety symptoms, while 23.7% had depression symptoms. Overall SSRS, subjective social support scores and objective support scores of patients with anxiety were lower than those of patients without anxiety. This result was also found in depression. In addition, all dimensions of social support were positively correlated with quality of life. Interestingly, in all dimensions of social support, subjective support was found to be an independent predictive factor for anxiety, depression, and quality of life, whereas objective support was a predictive factor for quality of life, but not for anxiety and depression via regression analysis. Conclusion: Medical staffs should pay attention to the subjective feelings of patients and make COVID-19 patients feel respected, supported, and understood from the perspective of subjective support, which may greatly benefit patients, alleviate their anxiety and depression, and improve their quality of life.

Environmental sampling of the severe acute respiratory syndrome coronavirus 2 Delta variant in the inpatient wards of a hospital in Nanjing.

BACKGROUND: Little is known about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant of concern (VOC)-contaminated environmental surfaces and air in hospital wards admitting COVID-19 cases. Our study was designed to identify high-risk areas of Delta VOC contamination in the hospital and provide suggestions to in-hospital infection control. We analyzed the SARS-CoV-2 Delta VOC contamination in the air and environmental surface samples collected from a hospital in Nanjing, China. METHODS: We collected data on clinical features, laboratory tests, swab tests, and hospital wards, identified the factors associated with environmental contamination, and analyzed patients' hygiene behaviors during hospitalization. RESULTS: A total of 283 environmental surface and air samples were collected from a hospital admitting 36 COVID-19 patients. Twelve swab samples from ten patients were positive. Toilet seats had the highest contamination rate (11.8%), followed by bedside tables (8.2%), garbage bins (5.9%), and bedrails (1.6%). The median time of symptom onset to surface sampling was shorter in the positive environment group than in the negative environment group (11 vs. 18 days; P=0.001). The results indicated that environmental surface contamination was associated with positive anal swabs [odds ratio (OR) 27.183; 95% CI: 2.359-226.063; P=0.003] and the time from symptom onset to surface sampling (OR 0.801; 95% CI: 0.501-0.990; P=0.046). The survey revealed that 33.3% of the patients never cleaned or disinfected their bedside tables or toilets, and 8.3% of them only cleaned their bedside tables or toilets. More than half of the patients often (25%) or always (30.6%) put the used masks on their bedside tables. Only 16.7% of the patients threw the masks into the specific garbage bin for used masks. CONCLUSIONS: The SARS-CoV-2 Delta VOC was detected on environmental surfaces, especially toilet seats and bedside tables, within a median time of 11 days after symptom onset. Our study provided potential predictors for environmental surface contamination, including positive anal swabs and the time from symptom onset to sampling. Disinfecting high-risk environmental surfaces should be emphasized in hospital wards, especially for patients in the early stage of COVID-19.

Vicarious traumatization in the general public, members, and non-members of medical teams aiding in COVID-19 control.

Since December 2019, more than 79,000 people have been diagnosed with infection of the Corona Virus Disease 2019 (COVID-19). A large number of medical staff was sent to Wuhan city and Hubei province to aid COVID-19 control. Psychological stress, especially vicarious traumatization caused by the COVID-19 pandemic, should not be ignored. To address this concern, the study employed a total of 214 general public and 526 nurses (i.e., 234 front-line nurses and 292 non-front-line nurses) to evaluate vicarious traumatization scores via a mobile app-based questionnaire. Front-line nurses are engaged in the process of providing care for patients with COVID-19. The results showed that the vicarious traumatization scores for front-line nurses including scores for physiological and psychological responses, were significantly lower than those of non-front-line nurses (P < 0.001). Interestingly, the vicarious traumatization scores of the general public were significantly higher than those of the front-line nurses (P < 0.001); however, no statistical difference was observed compared to the scores of non-front-line nurses (P > 0.05). Therefore, increased attention should be paid to the psychological problems of the medical staff, especially non-front-line nurses, and general public under the situation of the spread and control of COVID-19. Early strategies that aim to prevent and treat vicarious traumatization in medical staff and general public are extremely necessary.