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1.
Praxis (Bern 1994) ; 111(7): 389-395, 2022.
Article in German | MEDLINE | ID: mdl-35611480

ABSTRACT

Bariatric Surgery in 2022 - What Is Important for the General Practitioner? Abstract. Bariatric surgery is the most efficient treatment for obesity and associated diseases. Basic knowledge about the indications, common procedures, follow-up and possible complications has become essential for primary care practice. This article explains the current standards of care in Switzerland with a focus on relevant information for the practice: nutritional aspects after bariatric surgery, necessary clinical and laboratory examinations, early detection of complications. Only intense interdisciplinary and interprofessional collaboration leads to a treatment success in morbid obesity.


Subject(s)
Bariatric Surgery , Gastric Bypass , General Practitioners , Obesity, Morbid , Bariatric Surgery/methods , Gastrectomy/methods , Gastric Bypass/methods , Humans , Obesity, Morbid/surgery , Retrospective Studies , Treatment Outcome
2.
Obes Facts ; 14(1): 131-140, 2021.
Article in English | MEDLINE | ID: mdl-33333510

ABSTRACT

BACKGROUND: Currently, the two most common bariatric procedures are laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB). Long-term data comparing the two interventions in terms of their effect on body composition and bone mass density (BMD) are scarce. OBJECTIVE: The aim of this study was to assess body composition and BMD at least 5 years after LSG and LRYGB. SETTING: Department of Endocrinology and Nutrition, St. Claraspital Basel and St. Clara Research Ltd., Basel, Switzerland. METHODS: Bariatric patients at least 5 years after surgery (LSG or LRYGB) were recruited, and body composition and BMD were measured by means of dual-energy X-ray absorptiometry. Data from body composition before surgery were included in the analysis. Blood samples were taken for determination of plasma calcium, parathyroid hormone, vitamin D3, alkaline phosphatase, and C-terminal telopeptide, and the individual risk for osteoporotic fracture assessed by the Fracture Risk Assessment Tool score was calculated. After surgery, all patients received multivitamins, vitamin D3, and zinc. In addition, LRYGB patients were prescribed calcium. RESULTS: A total of 142 patients were included, 72 LSG and 70 LRYGB, before surgery: median body mass index 43.1, median age 45.5 years, 62.7% females. Follow-up after a median of 6.7 years. For LRYGB, the percentage total weight loss at follow-up was 26.3% and for LSG 24.1% (p = 0.243). LRYGB led to a slightly lower fat percentage in body composition. At follow-up, 45% of both groups had a T score at the femoral neck below -1, indicating osteopenia. No clinically relevant difference in BMD was found between the groups. CONCLUSIONS: At 6.7 years after surgery, no difference in body composition and BMD between LRYGB and LSG was found. Deficiencies and bone loss remain an issue after both interventions and should be monitored.


Subject(s)
Gastrectomy , Gastric Bypass , Absorptiometry, Photon , Adult , Body Composition , Body Mass Index , Female , Gastrectomy/methods , Gastric Bypass/methods , Humans , Laparoscopy/methods , Male , Middle Aged , Obesity, Morbid/surgery , Switzerland , Weight Loss
3.
Surg Obes Relat Dis ; 16(8): 1052-1059, 2020 Aug.
Article in English | MEDLINE | ID: mdl-32451228

ABSTRACT

BACKGROUND: Insufficient weight loss or secondary weight regain with or without recurrence of comorbidity can occur years after laparoscopic Roux en Y gastric bypass (LRYGB). In selected patients, increasing restriction or adding malabsorption may be a surgical option after conservative measures failed. OBJECTIVES: Evaluation of short and long term results of revisional surgery for insufficient weight loss or weight regain after LRYGB. SETTING: Tertiary hospital. METHODS: Retrospective analysis of prospectively collected data from a cohort of 1150 LRYGB patients. Included were patients, who underwent revisional bariatric surgery after LRYGB for insufficient weight loss with a follow-up of minimal 1 year. RESULTS: Fifty-four patients were included in the analysis. After an interdisciplinary evaluation, patients with insufficient weight loss, signs of dumping syndrome, and lacking restriction were offered a nonadjustable band around the pouch (banded group, n = 34) and patients with sufficient restriction, excellent compliance, and adherence were offered a revision to laparoscopic biliopancreatic diversion (BPD group, n = 20). The revisional procedure was performed 3.3 ± 2.3 years after LRYGB in the banded-group and after 6.4 ± 4.3 years in the BPD group (P = .001). Mean body mass index at the time of the primary bariatric procedure was 41.7 ± 6.2 kg/m2 in the banded group and 45.2 ± 8.2 kg/m2 in the BPD group (P = .08); minimal body mass index between both operations was 29.1 ± 4.7 kg/m2 in the banded group and 36.5 ± 9.4 kg/m2 in the BPD group, and, at the time of revisional surgery, 31.4 ± 5.5 kg/m2 in the banded group and 40.8 ± 6.7 kg/m2 in the BPD group (P = .0001). The mean body mass index difference 1 year after revisional surgery was 1.3 ± 3.0 kg/m2 in the banded group and 6.7 ± 4.5 kg/m2 in the BPD group (P = .01). In the banded group, 11 patients (32.4%) needed removal of the band, 4 patients (11.8%) needed an adjustment, and 4 patients (11.8%) were later converted to BPD. In the BPD group, 2 (10.0%) patients needed revision for severe protein malabsorption. CONCLUSIONS: Insufficient weight loss or secondary weight regain after LRYGB is a rare indication for revisional surgery. Banded bypass has modest results for additional weight loss but can help patients suffering from dumping. In very carefully selected cases, BPD can achieve additional weight loss with acceptable complication rate but higher risk for reoperation. Future "adjuvant medical treatments," such as glucagon-like peptide 1 analogues and other pharmacologic treatment options could be an alternative for achieving additional weight loss and better metabolic response.


Subject(s)
Bariatric Surgery , Gastric Bypass , Gastroplasty , Laparoscopy , Obesity, Morbid , Humans , Obesity, Morbid/surgery , Reoperation , Retrospective Studies , Treatment Outcome , Weight Loss
4.
Ther Umsch ; 76(3): 154-160, 2019 Sep.
Article in German | MEDLINE | ID: mdl-31498047

ABSTRACT

Medical Follow Up After Bariatric Surgery Abstract. The number of patients undergoing bariatric surgery to treat morbid obesity is increasing rapidly. Therefore it is an important issue to be aware of outcome and complications after bariatric surgery. This review presents a compilation of important gastrointestinal symptoms, as pain, diarrhea and dumping, and includes treatment options. It characterizes possible micronutrient deficiencies, gives instructions concerning the adaptation of drugs and illustrates possible adverse outcomes, such as excessive weight loss, insufficient weight loss and weight regain after bariatric surgery.


Subject(s)
Bariatric Surgery , Gastrointestinal Diseases , Obesity, Morbid , Postoperative Complications/prevention & control , Bariatric Surgery/adverse effects , Follow-Up Studies , Gastrointestinal Diseases/etiology , Humans , Obesity, Morbid/surgery , Weight Loss
5.
Surg Obes Relat Dis ; 13(8): 1313-1319, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28602794

ABSTRACT

BACKGROUND: In the past, laparoscopic adjustable gastric banding (LAGB) seemed to be a promising bariatric procedure. However, many studies showed high rates of reoperation due to complications or insufficient weight loss. There is a lack of long-term studies with follow-up beyond 15 years. OBJECTIVE: To conduct long-term follow-up of patients after LAGB and analyze their weight loss as a primary endpoint. SETTING: Tertiary referral center for bariatric surgery, St. Claraspital, Switzerland. METHODS: A retrospective analysis of prospectively collected clinical data in a cohort of 405 patients having undergone LAGB was performed. RESULTS: A total of 405 patients (age 41±10 years, body mass index [BMI] 44.3±6 kg/m2) were treated with LAGB between 1996 and 2010. Mean follow-up was 13±3 years, with a follow-up rate of 85% (range 8-18 years), corresponding to 343 patients. One hundred patients exceeded 15-year follow-up. In 216 patients (63%), sleeve gastrectomy, gastric bypass, or biliopancreatic diversion with duodenal switch was performed as revisional surgery. Twenty-seven patients (8%) refused revisional surgery after band removal. Finally, 100 patients (29%) still have the band in place, with a mean BMI of 35±7 kg/m2, corresponding to an excess BMI loss of 48±27%. Among these, the failure rate was 25%, according to the Bariatric Analysis and Reporting Outcome System (BAROS); 50% had a good to excellent outcome. CONCLUSION: More than 10 years after LAGB, 71% of patients lost their bands and only 15% of the 343 followed patients with the band in place have a good to excellent result, according to BAROS.


Subject(s)
Gastroplasty/methods , Laparoscopy/methods , Obesity, Morbid/surgery , Adolescent , Adult , Aged , Body Mass Index , Device Removal/methods , Device Removal/statistics & numerical data , Female , Follow-Up Studies , Gastrectomy/methods , Humans , Male , Middle Aged , Prosthesis Failure/etiology , Quality of Life , Recurrence , Reoperation/methods , Retrospective Studies , Treatment Outcome , Young Adult
6.
Langenbecks Arch Surg ; 401(3): 307-13, 2016 May.
Article in English | MEDLINE | ID: mdl-27001683

ABSTRACT

OBJECTIVE: In the course of laparoscopic Roux-en-Y gastric bypass (LRYGB), a tight gastroenterostomy (GE) may lead to higher weight loss but possibly to an increase of local complications such as strictures and ulcers. Different operative techniques for Roux-en-Y reconstruction may also influence the rate of internal hernias, a typical late complication of LRYGB. The objective of this study was to compare weight loss, rates of strictures, internal hernias, and ulcerations of linear versus circular stapler anastomosis. METHODS: Retrospective analysis of prospectively collected data in a 3:1-matched pair study. A total of 228 patients with a minimal follow-up of 2 years were matched according to BMI at baseline, age, and gender. The follow-up rate was 100 % at 1 and 2 years postoperatively; the mean follow-up time was 3.8 ± 1.63 years. In group C (circular), 57 patients were operated with a 25-mm circular stapler technique (average BMI 44.7 ± 5.18 kg/m(2), age 44.1 ± 10.8 years, 80.7 % female). In group L (linear), 171 patients were operated using a linear stapler (approximately 30 mm, average BMI 43.8 ± 5.24 kg/m(2), age 43.7 ± 12.5 years, 70.8 % female). A propensity score matching and a logrank test were used for statistical analysis. RESULTS: The average excessive BMI loss (EBMIL) after 1 year was not statistically different (70.6 ± 20.2 % in group C vs 72.5 ± 20.4 % in group L) as well as after 2 years (71.6 ± 22.5 % in group C vs 74.6 ± 19.6 % in group L). The average operation time was 155 ± 53 min in group C and 109 ± 57 min in group L (p = 0.0001). In group L, patients had significantly lower overall stricture rates at the GE compared to group C (0 [0 %] vs. 4 [7 %], p = 0.0004), a lower rate and severity of internal hernias (10 [5.8 %] vs. 7 [12.3 %] p = 0.466), and equal local ulcerations rates (3 [1.8 %] vs. 1 [1.8 %] p = 0.912). CONCLUSION: Linear stapler anastomosis in LRYGB compared to circular anastomosis leads to equal weight loss and less strictures. The lower rate of internal hernias in linear stapler anastomosis was not significantly different.


Subject(s)
Gastric Bypass , Laparoscopy , Obesity, Morbid/surgery , Surgical Stapling/methods , Adult , Anastomosis, Roux-en-Y , Body Mass Index , Female , Humans , Male , Matched-Pair Analysis , Middle Aged , Retrospective Studies , Treatment Outcome , Weight Loss
7.
Praxis (Bern 1994) ; 104(25): 1379-85, 2015 Dec 09.
Article in German | MEDLINE | ID: mdl-26649955

ABSTRACT

The number of patients undergoing bariatric surgery because of morbid obesity is increasing rapidly. Therefore, it is an important issue to be aware of outcome and complications after bariatric surgery. This mini-review presents a compilation of important gastrointestinal symptoms, as pain, diarrhea and dumping, and includes treatment options. It characterizes possible micronutrient deficiencies, gives instructions concerning the adaptation of drugs and illustrates possible adverse outcomes, such as excessive weight loss, insufficient weight loss and weight gain after bariatric surgery.


Subject(s)
Bariatric Surgery/adverse effects , Gastrointestinal Diseases/etiology , Postoperative Complications/etiology , Bariatric Surgery/methods , Gastrointestinal Diseases/therapy , Humans , Postoperative Complications/therapy , Treatment Outcome , Weight Loss
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