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2.
S Afr Med J ; 65(17): 693-4, 1984 Apr 28.
Article in English | MEDLINE | ID: mdl-6202013

ABSTRACT

The safety and efficacy of irrigation with a 1,5% glycine solution during transurethral resection of the prostate gland for benign hyperplasia were studied in 21 patients. Absorption of the irrigation solution during the procedure resulted in raised plasma glycine levels immediately after the operation, but these had virtually returned to normal within 24 hours. No adverse effects were noted and all the patients recovered uneventfully. This study demonstrates that glycine is well tolerated as an irrigation medium and appears to be free of complications.


Subject(s)
Glycine/administration & dosage , Prostatectomy/methods , Aged , Drug Evaluation , Glycine/standards , Humans , Male , Middle Aged , Prostatic Hyperplasia/surgery , Safety , Solutions , Therapeutic Irrigation
3.
S Afr J Surg ; 15(1): 56-7, 1977 Mar.
Article in English | MEDLINE | ID: mdl-867168
4.
Int J Fertil ; 20(1): 1-4, 1975.
Article in English | MEDLINE | ID: mdl-4378

ABSTRACT

Twenty-one males with azo- or oligospermia presenting with infertility and with no evidence of organic disease were studied with luteinizing hormone - releasing hormone (LH-RH). A pituitary luteinizing hormone (LH) and follicle stimulating hormone (FSH) response was present in all cases and was normal in the majority of the subjects. Serum testosterone and 17 beta estradiol levels were normal in all cases studied. No significant correlations were found between the gonadotropin estimations and sperm count, basal serum testosterone or testosterone response to human chorionic gonadotropin. It is concluded that LH-RH is of limited diagnostic use in the investigation of this group of patients with male infertility and provides no further insight into the pathogenesis of this condition.


Subject(s)
Follicle Stimulating Hormone/metabolism , Gonadotropin-Releasing Hormone , Infertility, Male/physiopathology , Luteinizing Hormone/metabolism , Oligospermia/physiopathology , Pituitary Gland, Anterior/physiopathology , Pituitary Gland/physiopathology , Adult , Estradiol/blood , Humans , Male , Middle Aged , Pituitary Gland, Anterior/metabolism , Testosterone/blood
9.
Br Med J ; 3(5724): 670-2, 1970 Sep 19.
Article in English | MEDLINE | ID: mdl-4919023

ABSTRACT

In a series of 27 recipients of cadaver kidney grafts, 26 were at the time of writing alive, 3 to 25 months after transplantation, and 25 patients were alive with functioning first grafts. The one-year patient survival in 18 patients was 94% and the one-year graft survival was 89%. There was no beneficial correlation between tissue matching and the frequency of major early rejection episodes or graft function 12 or more months after transplantation. Antilymphocyte globulin administration was associated with a lower incidence of early rejection episodes, but this was not statistically significant. A combination of prophylactic graft irradiation and antilymphocyte globulin administration for at least the first two weeks was associated with a significantly reduced frequency of major early rejection episodes and appreciably better graft function at 12 months. This effect could not be ascribed to better tissue matching.


Subject(s)
Antilymphocyte Serum/therapeutic use , Histocompatibility Testing , Kidney Transplantation , Radiotherapy , Cadaver , Cobalt Isotopes , Creatinine/blood , Female , Humans , Immunosuppressive Agents/therapeutic use , Male , Transplantation Immunology , Transplantation, Homologous
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