[Treatment of tracheoesophageal and tracheopharyngeal fistulas after laryngectomy]. / Therapie der tracheoösophagealen und tracheopharyngealen Fisteln nach Laryngektomie.

Tracheoesophageal (TEF) and tracheopharyngeal fistulas (TPF) after laryngectomy can mainly be divided into five types: "high TEF with leakage through the voice prosthesis (VP)" (Type Ia), "high TEF with leakage around the VP" (Type Ib), "enlarged high TEF" (Type II), "deep TEF" (Type III), "TPF" (Type IV) and "TPF associated with pharynx stenosis" (Type V). Leakage of TEF in prosthetic voice restoration usually responds well to conservative measures. If these measures fail, as well as in all cases of TPF, surgical intervention is necessary for transtracheostomal or transcervical closure with multi-layer sutures of the esophagus and trachea. In persisting TEF/TPF after unsuccessful surgical attempts revision surgery remains challenging. Tracheostoma transposition for dissociation of the cranial end of the trachea and the hypopharynx and esophagus is essential for effective closure. In rare cases of TPF combined with pharyngoesophageal stricture formation a resection and immediate reconstruction of the stenotic pharyngoesophageal segment with a tube-shaped fasciocutaneous radial forearm flap must be considered.

[Posttraumatic gusher phenomenon following fracture of the petrous bone]. / Posttraumatisches Gusher-Phänomen nach Felsenbeinquerfraktur.

The gusher phenomenon is a very rare complication that may occur during stapedectomy or cochleostomy. A sudden perilymphatic flow of cerebrospinal fluid can be seen following platinotomy. The cause is an abnormal connection between subarachnoid and perilymphatic spaces due to congenital malformation, leading to an abnormally wide cochlear aqueduct or due to an internal auditory canal fistula. We describe a case of posttraumatic gusher phenomenon after a fracture of the petrous bone.

[Brachytherapy in combination with function-preserving surgery. An interdisciplinary challenge]. / Brachytherapie in Kombination mit zurückhaltender Chirurgie. Eine interdisziplinäre Herausforderung mit dem Ziel des Organerhalts.

A multimodal, interdisciplinary approach known as intensity-modified brachytherapy is a promising alternative for patients with advanced head and neck cancer infiltrating the orbita and skull base. An 87-year-old man presented with a recurrence of squamous cell carcinoma of the medial corner of the left eye that had been locally resected and irradiated by external beam radiotherapy multiple times. The cancer was resected with preservation of the eye with close margins, implantation of afterloading catheters, and reconstruction of the defect with a median forehead flap. The patient was irradiated with a total radiation dose of 30 Gy IMBT. After 1 year, there was no evidence of locoregional recurrence. The background of this therapeutic process and analysis of the current literature regarding this interdisciplinary treatment of head and neck cancer infiltrating the orbita and skull base are discussed based on this case report.

[Unilateral extended medialization thyroplasty. Treatment for total aspiration after laser surgery and radiotherapy of laryngeal cancer]. / Einseitige erweiterte Medialisierungs-Thyroplastik. Therapie der kompletten Aspiration nach laserchirurgischer Resektion und Strahlentherapie des Larynxkarzinoms.

BACKGROUND: Total aspiration is a rare complication after extended laser surgery for laryngeal cancer with adjuvant radiotherapy. PATIENTS AND METHODS: Two patients with long-standing total aspiration after laser surgery with radiotherapy despite intensified swallowing therapy were treated with an extended medialization thyroplasty. RESULTS: Postoperatively, both patients were able to swallow food and liquids without aspiration. One patient no longer has a gastrostomy tube and has been free from aspiration with normal oral food intake for 3 years. The second patient, with a tiny mucosal scar perforation, developed an abscess 2 months after surgery and needed revision surgery, with a subsequent return of aspiration. DISCUSSION: The second patient's complication stresses the significance of an intact endolaryngeal scar because of the well-known prolonged healing of mucosa in the irradiated larynx. In our opinion, the potential benefits of medialization thyroplasty outweigh the risk of significant complications, especially after irradiation.

[Surgery of benign tumors of the parotid gland: the value of fine needle aspiration cytology]. / Gutartige Tumoren der Glandula parotidea: Präoperative Aspirationszytologie und chirurgische Strategie.

BACKGROUND: Fine needle aspiration cytology (FNAC) is a widely used diagnostic tool to evaluate neoplastic or inflammatory tumorous lesions of the salivary glands. This method influences the selection of the modality of surgical treatment. In cases of benign tumors of the parotid gland, a (partial) superficial parotidectomy is usually recommended. However, for tumors other than pleomorphic adenomas (such as cystadenolymphomas, other adenomas, or benign tumor-like lesions) this operation is considered an overtreatment because extracapsular satellites are rare and recurrences in case of a capsular lesion are not likely. In such cases, a less extended surgery (enucleation) with lower morbidity is sufficient and can be carried out provided that pleomorphic adenomas and non-pleomorphic benign lesions are reliably differentiated prior to surgery. The aim of this study was to evaluate the reliability of the FNAC in differentiating benign tumors of the parotid gland. METHODS: A retrospective evaluation of 160 cases of benign parotid gland tumors was performed and the cytological diagnoses compared with the histomorphological results. A collection of 26 cases with false-negative and false-positive results was reevaluated. RESULTS: FNAC showed a sensitivity of 74.2% and a specificity of 89.8% for differentiation between pleomorphic adenomas and non-pleomorphic benign lesions. The predictive value for pleomorphic adenomas was 82.1%, and for non-pleomorphic benign lesions 84.6%. Reevaluation showed higher sensitivity (96.2%), specificity (98.9%), and negative/positive predictive values (97.9% and 98.1%, respectively). DISCUSSION/CONCLUSION: Poor quality and hypocellularity of the cytological smears seem to negatively effect the outcome of the cytological diagnosis. It is concluded that only an accurate diagnosis of non-pleomorphic adenoma or a benign tumor-like lesion, based on an adequate FNAC specimen and assessed by an experienced cytopathologist, can justify tumor enucleation because the risk of pleomorphic adenoma is only 2% under these circumstances.

[Integration of the active middle ear implant Vibrant Soundbridge in total auricular reconstruction]. / Integration des aktiven Mittelohrimplantates in die plastische Ohrmuschelrekonstruktion.

BACKGROUND: Patients with high-grade microtia and atresia require a sophisticated and specific treatment. Apart from the plastic reconstruction of the auricle, in some cases hearing rehabilitation is medically indicated or is desired by the patients. The long-term results of simultaneous middle ear reconstruction with tympanoplasty are often inadequate owing to a persisting air-bone gap, and new techniques in hearing rehabilitation are needed for these patients. METHODS: We present three cases of unilateral atresia to illustrate a combined approach integrating hearing rehabilitation using the active middle ear implant Vibrant Soundbridge (VSB) into plastic auricular reconstruction. The VSB was attached to the stapes suprastructure via the titanium clip in two of these cases and in the third case a subfacial approach was used to attach it directly to the membrane of the round window. RESULTS: The air-bone gap was reduced to 17 dB, 14 dB and 0.25 dB HL. In free-field speech recognition tests at 65 dB SPL the patients achieved 100%, 90% and 100% recognition with the activated implant. No postoperative complications such as facial nerve paresis, vertigo or inner ear damage were found. CONCLUSIONS: The integration of active middle ear implants in auricular reconstruction opens up a new approach in complete hearing rehabilitation. The additional implantation of the VSB does not have any negative effect on the healing process or the cosmetic outcome of the auricular reconstruction.

[Reconstruction of the auditory canal wall with bone chips from the temporal squama--preliminary results]. / Rekonstruktion der Gehörgangswand mit Knochenchips aus der Temporalschuppe--Erste Ergebnisse.

BACKGROUND: The canal wall down-technique in cholesteatoma surgery with the creation of an open mastoid cavity offers many disadvantages as prolonged healing time, necessity for periodic cleaning and subsequent infections. Therefore reconstruction of the posterosuperior canal wall is the more and more preferred technique to restore the physiologic anatomy of the external auditory canal without lacking a good surgical exposure to the tympanal and retrotympanal spaces. Cartilage is the mainly used material for this technique, as cartilage is easy to prepare and to fit into the defect with good viability. However, cartilage resorption and retraction is observed increasing the risk for recurrent cholesteatoma. In contrast, by the use of bone chips from the temporal squama a stable and close restoration of the auditory canal wall can be achieved. PATIENTS AND METHODS: In 23 patients (17 attic and 6 sinus cholesteatomas including two recurrences in each group) we have performed an anterior atticoantrostomy with retrograde cholesteatoma removal and reconstructed the posterosuperior wall of the auditory canal with bone chips harvested from the temporal squama by chisels. The bone chips and remaining gaps in the reconstructed wall were covered by bone paté and temporal fascia. In 4 cases the ossicular chain could be conserved (type-1 tympanoplasty [TP]), type-3 TP with PORP was performed in 13 and TORP-TP in 6 cases. The mean follow-up was 12.1 months (range 4 - 34 months). 8 patients had undergone a second-look procedure. RESULTS: On follow-up all patients showed a good healing of the external ear canal with no graft insufficiency. In one case we observed a slight ear canal narrowing due to bone excess, three patients developed retraction pockets of the attic. Recurrent cholesteatoma was not seen yet. Second-look tympanotomy revealed complete ingrowth of the transplanted bone chips into the surrounding bony structures in all cases. One residual cholesteatoma had to be removed and the canal wall had to be reconstructed again with bone chips. The average postoperative air-bone gap was 7.0 +/- 8.2 dB HL for type-1 TP, 8.6 +/- 3.0 dB HL for PORP-TP (83 % [100 %] of the patients < or = 10 dB HL [< or = 20 dB HL]) and 19.3 +/- 9.2 dB HL for TORP-TP (66 % of the patients < or = 20 dB). CONCLUSIONS: Osteoplastic atticoantrostomy allows adequate anatomic and physiologic restoration of the auditory canal even after extensive cholesteatoma removal. Bone stability may reduce recurrent cholesteatoma. However, due to the underlying impaired tubal function long-time results must be further evaluated.

[Surgery of the parapharyngeal adenomas]. / Chirurgie der parapharyngealen Adenome.

Pleomorphic adenomas are the most common tumors of the parapharyngeal space (PPS) and often grow to an enormous size before becoming visible or symptomatic. CT and MRI scans are important in both diagnosis and surgical treatment. There are basically four different surgical approaches (transoral-transpalatal, transcervical-submandibular, transparotid und transmandibular) to the anterior PPS. Wide and direct exposure of the PPS is provided by a midline mandibulotomy with transection of the floor of the mouth. Owing to its morbidity this approach is reserved exclusively for extended tumors. The transcervical-submandibular route with blunt finger dissection generally offers adequate access for total tumor removal. For adenomas arising from the parotid gland a transparotid approach may be utilized. Adenomas located medially are better be resected transorally by splitting the soft palate.

Persistence of perilymph fistula mechanism in a completely paretic posterior semicircular canal.

The three dimensional eye movements (search coil technique) of a patient with a completely paretic left posterior semicircular canal as a result of a perilymph fistula (PLF) were studied. The patient still exhibited pressure induced nystagmus that obeyed Ewald's first law. This finding cannot be explained by otolith stimulation, but might indicate that PLF mechanisms either persist in canal plugging or act on the ampulla by directly deflecting the cupula.

Voluntary palatal tremor is associated with hyperactivation of the inferior olive: a functional magnetic resonance imaging study.

Voluntary palatal tremor in a patient with essential palatal tremor induced activation predominantly within regions corresponding to the inferior olive, adjacent brainstem, and dentate nuclei. Finger movements elicited only ipsilateral lobular cerebellar activation, suggesting a dysfunctional nuclear activation by palatal tremor.

[Electromyography of the infrahyoid muscles - part 1: normal findings]. / Elektromyographie der Infrahyoidalmuskulatur - Teil 1: Normalbefunde -

BACKGROUND: The infrahyoid muscles (IHM) are very useful as a neurovascular myofascial flap in plastic reconstructive surgery of the upper aerodigestive tract, especially for restoration of the muscular component in larger tongue defects. As a base for further postoperative investigations on the function of transferred IHM this first part of the study describes the physiological function and the electromyographical features of the IHM. METHODS: In 17 patients with cancer of the upper aerodigestive tract the sternohyoid and sternothyroid muscles and in additionally eight patients the upper part of the omohyoid muscle were studied electromyographically. Muscular activity was recorded at various movements and maximal voluntary innervation. In ten healthy volunteers the motor unit potentials (MUP) during light voluntary innervation of these muscles were studied. RESULTS: In both muscles we found the steadist and strongest muscular activity at isometric head bending and yaw opening, in the omohyoid muscle also at head rotation. At swallowing and breathing in (2/3) of the cases muscular activity could be recorded. Amplitudes and electromyographic charge pattern in comparison were diminished. Phonation und tongue movements showed no noticable muscular activity. Analysis of the MUP in 10 healthy volunteers showed a mean amplitude of 274 +/- 59 microV and a mean duration of 8.5 +/- 0.6 ms. CONCLUSIONS: The presented study demonstrates that EMG of the IHM are recorded best while head bending, yaw opening and head rotation. Since there is no interchange of nerve fibres between the hypoglossal nerve and the cervical ansa it should be possible to differentiate between original tongue muscles and transferred muscles in electromyographic studies of myofascial flaps after tongue reconstruction.

[Electromyography of the infrahyoid muscles - part 2: pathological findings]. / Elektromyographie der Infrahyoidalmuskulatur - Teil 2: Pathologische Befunde nach Vorschäden im Halsbereich -

BACKGROUND: The infrahyoid muscles (IHM) can easily be used as a neurovascular myofascial flap for reconstructive surgery in the oral cavity and pharynx and especially for functional tongue reconstruction following tumor ablation. METHODS: In order to detect neurogenic lesions caused by neck pathologies, in particular lymph node metastasis, we studied ten patients (nine patients suffering from tongue carcinoma and one patient after traumatic tongue ablation) by preoperative electromyography of the IHM. These results were compared to ten healthy controls. RESULTS: We found no pathological spontaneous activity with the EMG at rest in any patient. During light voluntary innervation, the motor unit potentials (MUP) were normal in controls and in patients with normal ultrasound, CT scans and histologic examination after neck surgery. When pathologic lymph nodes were found in the neck, the number of polyphasic MUP in the ipsilateral IHM was increased in some cases (n = 6), and normal in others (n = 5). Traumatic or radiogenic lesions clearly resulted in pathological EMG findings (n = 6). Maximal innervation of the IHM was obtained during head bending and jaw opening. We found no difference in the discharge pattern of both groups. CONCLUSIONS: Due to their extent lymph node metastasis can lead to neurogenic lesions of the cervical ansa of the IHM. Neurogenic damages are most clearly present after traumatic lesions of the neck (prior operations, radiotherapy). EMG at maximal voluntary contraction instead revealed no lesions. The clinical impact of these demonstrated neurogenic lesions need to be studied by measuring the muscle strength of the IHM.

[Electromyography of the infrahyoid muscles - part 3: findings after transposition as a myofascial flap in tongue reconstruction]. / Elektromyographie der Infrahyoidalmuskulatur - Teil 3: Befunde nach Transposition des Muskelfaszienlappens zur Zungenrekonstruktion -

BACKGROUND: Due to the preservation of its nerval supply the neurovascular infrahyoid muscle flap in tongue reconstruction enables to prevent atrophy of the musculature. In this study the integrity of the infrahyoid muscles (IHM) after transposition into the oral cavity was examined by means of electromyography. METHODS: 17 patients after partial or complete reconstruction of the tongue with IHM were studied at varied times after surgery. The IHM in the oral cavity was inserted by a concentric needle electrode and activity at rest as well as the discharge pattern at maximal voluntary innervation was evaluated. During light voluntary activity a motor unit potential (MUP) analysis were performed. RESULTS: 13 of 17 patients (76,5 %) in total revealed electromyographic activity in the transfered IHM flaps. Within the first 6 months after surgery 71,5 % of the patients or 77,8 % of the IHM flaps showed activity. After 6 months in 61,5 % of the patients or 64,7 % of the IHM flaps muscular activity was demonstrated. In 84,6 % of the patients or 88,2 % of the flaps we could detect neurogenic lesions at least once. Maximal voluntary contraction showed a discrete activity pattern in 63 %. In 26 % of all cases we found a discrete to reduced interference pattern and in 10 % a reduced interference pattern. CONCLUSIONS: Functioning muscle tissue could be demonstrated in the most IHM flaps, but almost all of the studied muscles showed neurogenic lesions with a loss of motor units due to the traumatic surgery. Maybe bioelectrical stimulation of the Ansa cervicalis with implantable amplifiers will lead to better flap contractility in the future.

[Transplants from the shoulder-back region]. / Transplantate der Schulter-Rücken-Region.

BACKGROUND: In spacious or multilayered tissue losses and cases of multiple locations of defects, a large amount of tissue with different components such as skin, fatty tissue, and muscle is required for proper reconstruction. A donor area which can meet these demands is the shoulder-back region with the subscapular vessel, which arises from the axillary artery. PATIENTS AND METHODS: We report our clinical experience with 12 patients in whom we reconstructed defects with transplants from this region. RESULTS: Our anatomic investigation and measurements provided proof of a constant anatomy of the vessels with a length of the vascular pedicle and a vascular diameter suitable for microvascular anastomosis. Based on our clinical experience, the scapular, parascapular, and latissmus dorsi muscle transplants are very suitable for the reconstruction of very large superficial defects or for the augmentation of multilayered defects of the upper aerodigestive tract. CONCLUSIONS: A main advantage of the transplants from the shoulder and back region is the possibility of combining several transplants with a wide variety of tissue combinations with one vascular pedicle for a single-step reconstruction of multiple defects of the oral cavity and the pharynx.

[Main symptom: "pulse-synchronous tinnitus"]. / Hauptsymptom: "Pulssynchrones Ohrgeräusch".

BACKGROUND: In comparison to cochlear or nerval generated ear noises, pulsatile tinnitus is a rare condition. Due to its own etiology, specific diagnostic steps are necessary. PATIENTS: We present 6 patients with pulsating tinnitus as the leading symptom. By means of these cases the various etiologies, rational diagnosis and therapy will be discussed. RESULTS: Pulsatile tinnitus is frequently caused by an increased blood flow in the cranial vessels through various pathologies. Besides those diseases going along with a general increase of blood circulation, regional alterations can be classified as hypervascular/hyperemic, arterial or venous conditioned. CONCLUSIONS: Physical examination and modern imaging can detect the underlying reasons in a quick and reliable way.

Electromyography of the infrahyoid muscles: pathological and normal findings.

UNLABELLED: In recent years, the infrahyoid muscles (IHM) have been used by plastic reconstructive surgeons as a neurovascular muscle flap in the neck and mouth region. METHODS: A preoperative electromyographic examination (EMG) of the IHM was performed in 10 patients, of whom 9 suffered from tongue cancer, in order to detect neurogenic lesions caused by possible metastases or lymph nodes. The results were compared to those of 10 healthy controls. RESULTS: The EMG at rest showed no pathological spontaneous activity in any patient. During light voluntary innervation, the motor unit potentials (MUPs) were normal in controls and in patients with normal sonographic images, computertomographic scans, and histologic findings after surgery in the neck region. When metastatic lymph nodes were found on one side of the neck, the number of polyphasic MUPs in the IHM of that side was increased in some cases (n = 6), and normal in others (n = 5). Traumatic or radiogenic lesions clearly resulted in pathological EMG findings (n = 6). A maximal innervation of the IHM was achieved during head bending and jaw opening, there was no activation of the IHM with tongue movements and vice versa. CONCLUSIONS: If the presence of lymph node pathology was demonstrated using imaging techniques, a resulting lesion of the ansa cervicalis can functionally be demonstrated by EMG. In patients without lymph node metastases and without concurrent other lesions in the cervical region, EMG of the IHM seems to give no further clinical information. A clear postoperative functional differentiation of the transplanted IHM and the indigenous tongue muscles is possible.

[Microsurgical reanastomosis of the parotid duct]. / Mikrochirurgische Reanastomosierung des Ductus parotideus.

Deep injuries to the parotid region may result in trauma to vital structures: i.e., the parotid gland and duct and the facial nerve and its branches. While there is no doubt concerning primary microsurgical reconstruction of injuries to the facial nerve clinical approaches for treating disruptions of the parotid duct have been controversial. A case report is presented of a secondarily reanastomosed parotid duct following complete transection. The microsurgical technique and its indications are discussed.

[Topographic and anatomic study of lateral upper arm transplants]. / Topographisch-anatomische Studie des lateralen Oberarmtransplantats.

An anatomic and topographic study of the lateral upper arm free flap for the clinical use in reconstruction. Defects of the laryngopharynx and the oral cavity after cancer ablation are increasingly reconstructed by free microvascular anastomosed tissue transfer. Besides the jejunum transplant we use the free radial forearm flap frequently. This flap is suitable for restoring intraoral and pharyngeal integrity. Major disadvantages are the requirement of a skin graft to obtain wound closure and the cosmetic deformity. The lateral upper arm free flap is intended as alternative method for the fasciocutaneus tissue transfer. Based on our dissection of ten cadavers we demonstrate the anatomy of the flap, the harvesting technique, and present data of vascular pedicle length, vessel calibers, and flap size. The vessel calibers of the profound brachial artery (X = 2.5 mm) and its terminal branch, the posterior radial collateral artery (X = 1.8 mm), are comparable to the radial artery. The pedicle length can be extended up to 13 cm by using a lateral approach. The subcutaneous tissue volume was 1.3 cm in average, and compared to the radial flap rather thick. Because of his bulky and strong fascia the lateral arm flap seems to be useful as a fascia-fat flap in facial augmentation or as a fascia flap in soft tissue reconstruction. Disadvantageous are the difficult dissection technique and the loss of sensitivity on the lateral aspect of the forearm. Where a fasciocutaneous flap is indicated, we prefer the radial forearm flap.

Voluntary palatal tremor in two siblings.

We report two siblings with palatal tremor (PT) and ear clicks who can voluntarily elicit or suppress both PT and ear clicks by just "thinking" about starting or stopping the sounds. The patients were also able to voluntarily modulate the frequency of their ear clicks and PT. They did not have any signs of cerebellar, brain stem, or other neurologic disease. These familial palatal movements may represent a variant of palatal tremor but can not satisfactorily be classified as either symptomatic or essential PT.