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Pharmazie ; 53(10): 686-90, 1998 Oct.
Article in English | MEDLINE | ID: mdl-9812334

ABSTRACT

2-Acetyl-4-(p-chlorophenyl)-3-(1-pyrrolyl)-5,6,7,8- tetrahydrothieno[2,3-b]quinoline (4a) and its corresponding 2-carbohydrazide derivative 5 were prepared and used as key intermediates in the synthesis of the title compounds. Some of the synthesized compounds were screened for their antibacterial and antifungal activities.


Subject(s)
Anti-Infective Agents/chemical synthesis , Quinolines/chemical synthesis , 4-Quinolones , Anti-Infective Agents/pharmacology , Bacteria/drug effects , Fungi/drug effects , Microbial Sensitivity Tests , Quinolines/pharmacology , Structure-Activity Relationship
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