ABSTRACT
Virological, serological and immunofluorescence studies revealed circulation of rhinoviruses of the strains 1A, 1B, 2, 3, 7, 9, 10, 12, 13, 14, 16-23, 27, 29-33, 42, 48, 53, 56, 60 and 69 on the territory of Czechoslovakia and the Soviet Union. According to virological results, type 48 predominated and was followed in frequency of occurrence by types 27, 14 and 16 in the USSR and 30, 1A and 31 in the CSSR. RV infection in adults with ARD diseases was the aetiology in 28.5% of cases. Among the causative agents of acute rhinitis, rhinosinusitis and otitis, rhinovirus infection makes up a large proportion. Interrelation has been found between rhinovirus infection and chronic inflammation of the mucosa of the nose, the accessory sinuses and the ears. Prolonged course of rhinovirus infection and isolation of the virus in the late stages of disease (1-4 months after its onset) support the presumption that rhinoviruses promote chronicity of inflammation. RV was isolated from patients with chronic pneumonia from the lower respiratory passages (bronchial secretion). Rhinoviraemia was found in a child who died of ARD.
Subject(s)
Picornaviridae Infections/epidemiology , Rhinovirus/isolation & purification , Adolescent , Adult , Aged , Antibodies, Viral/analysis , Child , Child, Preschool , Czechoslovakia , Humans , Infant , Middle Aged , Otorhinolaryngologic Diseases/etiology , Picornaviridae Infections/immunology , Pneumonia, Viral/etiology , Respiratory Tract Infections/etiology , Rhinovirus/classification , Rhinovirus/immunology , Serotyping , USSRSubject(s)
Otorhinolaryngologic Diseases/etiology , Virus Diseases/epidemiology , Adolescent , Adult , Aged , Humans , Middle AgedABSTRACT
In the period of 1971--1973 in Moscow, 85 strains of rhinoviruses (types IB, 14, 20, 27, 33, 48, 56, 60 and 69) were isolated from patients with respiratory diseases. In March-May 1971 in one administrative district of Moscow, from ambulatory patients with ARD rhinoviruses of types 48 (24 strains) and 27 (8 strains) were predominantly isolated. An outbreak of diseases due to these two types appeared to have occurred. From children rhinoviruses were isolated not only from nasopharyngeal washings. From 3 children they were isolated from the lower respiratory tract (from the blood collected before his death due to staphylococcal sepsis. Surveys for virus-neutralizing antibody to 17 rhinovirus serotypes in 10 lots of gamma globulin prepared in different towns of the Soviet Union revealed wide spread of rhinovirus types IB, 13, 18, 31 and 32 limited spread of types 17 and 42 and moderate spread of types 2, 3, 7, 10, 14, 21, 22, 24, 48 and 53.
