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1.
Front Sports Act Living ; 6: 1346637, 2024.
Article in English | MEDLINE | ID: mdl-38746828

ABSTRACT

Introduction: Demographic changes are resulting in a continual increase in the proportion of individuals over 65 years old. Simultaneously, muscle mass (MM) tends to decrease with age, with a decline noticeable from the middle of the fourth decade of life. While physical activity is considered a modulator for maintaining MM, the interaction with nutrient uptake, especially protein intake, is getting more into focus. Due to a lack of data on the effect of a high-protein diet on middle-aged individuals (40-65 years), this study aimed to investigate the influence of a high-protein diet in middle-aged physically active persons on body composition and performance. Methods: Using stratified randomization, participants were allocated to either a high-protein group (>2.3 g/kg FFM/day) (n = 12, age = 57.83 ± 7.74 years, height = 170.42 cm ± 11.04 cm, BMI = 30.26 ± 4.46, MM = 31.71 ± 6.89 kg) or a control group (<2.3 g/kg/FFM/day) (n = 14, age = 58.21 ± 6.44 years, height = 170.57 cm ± 8.28 cm, BMI = 26.31 ± 5.59, MM = 29.67 ± 8.08 kg). Body composition [fat-free mass (FFM), fat mass (FM), MM] and strength were assessed at baseline (T0), after four weeks (T1) and after eight weeks (T2). Exercise habits were not changed over the entire period and dietary habits were recorded using FDDB Explorer. Statistical analysis was performed using the current version of R and linear mixed models. Results: No significant differences in energy intake were found between the groups (p = .974). In macronutrient distribution, a significantly higher consumption of protein was found in the high-protein group (p < .0001, d = 2.22) [140 ± 70 g/day (HPG) vs. 79 ± 40 g/day (CG)]. A trivial reduction in FM over time in both groups (p = .046, d = 0.04, Δt=-.83±1.60kg) was observed. No significant differences were detected in FFM (p = .887) and MM (p = .711). Trivial interaction effects (time*group) were observed for upper (p = .007, d = 0.12, ΔHPG = 4.38 ± 3.25 kg) and lower body strength (p = .0507, d = 0.07, ΔHPG = 3.33 ± 2.36 kg). Discussion: Our results indicate no to only trivial effects of adding a high-protein diet to otherwise physically active middle-aged individuals. Trivial effects could be seen for an increase in muscle strength after this eight-week intervention. However, MM and FFM were not significantly affected. Based on the small effect sizes we observed in our results we do not see a benefit of a high-protein diet on body composition and strength capacity without altering the exercise habits.

2.
Nutrients ; 16(3)2024 Jan 27.
Article in English | MEDLINE | ID: mdl-38337659

ABSTRACT

BACKGROUND: The consumption of dietary supplements (DS) is widespread among the general population and competitive athletes. However, only a few competitive athletes seek information from experts about the effects and use of DS. Furthermore, it is currently unknown whether certain sports have a higher affinity for DS than others. METHODS: This study aimed to identify differences between different sports categories and subgroups that may have a very high affinity for DS. For this purpose, competitive athletes were surveyed. The survey included the type of sport, the training frequency, the number of competitions, the consumption behaviour of five DS categories (general health, regeneration promotion, performance enhancement, booster, and weight loss) as well as personal data such as biological sex and age. Subsequently, correlations, configural frequencies (CFA), and multiple correspondence analyses (MCA) were used to identify subgroups with a high affinity of consumption behaviour. RESULTS: A total of 409 questionnaires could be evaluated. It was found that all DS categories except weight loss were related. In addition, it was observed that in sports from the power category and from the endurance category, there was even higher consumption behaviour than in other sports categories. Male power athletes in particular have a higher affinity for consuming DS than other subgroups. CONCLUSIONS: This study shows that there is a clear different consumption behaviour depending on the type of sport. Male power athletes in particular are the subgroup with the greatest consumption behaviour and therefore require special education on the effects and use of DS. This subgroup in particular should receive increased attention in counselling on DS to minimise the possible risks of DS use.


Subject(s)
Doping in Sports , Sports , Humans , Male , Dietary Supplements , Athletes , Weight Loss
3.
J Sports Sci Med ; 22(4): 778-789, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38045750

ABSTRACT

The purpose was to compare the electromyographic (EMG) activity of the Hang Power Clean (HPC) and Hang Power Snatch (HPS) with the Hang Clean Pull (HCP) and Hang Snatch Pull (HSP). Additionally, the influence of weightlifting expertise (beginner, advanced and elite) on EMG activity was analyzed. Twenty-seven weightlifters (beginner: n = 11, age: 23.9 ± 3.2 years, bodyweight: 75.7 ± 10.5 kg; advanced: n = 10, age: 24.8 ± 4.5 years, bodyweight: 69.4 ± 13.9 kg; elite: n = 6, age: 25.5 ± 5.2 years, bodyweight: 75.5 ± 12.5 kg) participated in this study. Participants performed two repetitions of HPC, HPS, HCP, and HSP at 50%, 70%, and 90% 1RM, respectively. The EMG activity of vastus lateralis (VL), gluteus maximus (GM), erector spinae (ES), rectus abdominis (RA) and trapezius (TZ) was recorded and normalized to the maximum voluntary isometric contraction (MVIC) of each muscle. There were significant differences in RA and ES EMG activity at 70% and 90% 1RM during HPC compared to HCP in the beginner group (p < 0.05, Hedges g = 0.50-1.06). Significant greater ES activity was observed in the beginner, advanced, and elite groups (p < 0.05, g = 0.27-0.98) during the HPS when compared to the HSP at 50-90% 1RM. TZ muscle activity was significantly greater at 50% and 70% 1RM in the HCP compared to the HPC in the elite group (p < 0.05, g = 0.61-1.08), while the beginner group reached significance only at 50% 1RM favoring HPC (p < 0.05, g = 0.38). Moreover, the EMG activity of the TZ during the HSP and HPS was significantly different only at 50% 1RM in the elite group and favored HSP (p < 0.05, g = 0.27). No differences were observed between the levels of weightlifting expertise. Based upon the results of this study, the overall pattern of EMG activity of the predominant muscles involved in HPC/HPS and the corresponding weightlifting pulling derivatives, apart from the stabilizing muscle (RA and ES), is similar at higher intensities (>70% 1RM) and expertise does not influence muscle activity.


Subject(s)
Resistance Training , Humans , Young Adult , Adult , Resistance Training/methods , Muscle, Skeletal/physiology , Quadriceps Muscle/physiology , Exercise/physiology , Buttocks
4.
BMC Womens Health ; 23(1): 526, 2023 10 06.
Article in English | MEDLINE | ID: mdl-37803287

ABSTRACT

BACKGROUND: Resistance training (RT) is effective in counteracting the age- and menopause-related loss of muscle mass (MM) and strength in middle-aged women (40-60 years). Research on RT with free weights is limited in pre- and post-menopausal women. Based on this, a 20-week training intervention was conducted with this population to investigate the effects of systematic RT with free weights on strength capacity and body composition. METHOD: Forty-one healthy women (52.0 ± 3.6 years) participated in this study. After 10-week control phase (no RT, T0-T1) followed by a 10-week intervention phase (T1-T2) with RT twice a week and 6-8 sets of each muscle per week. Subjects were randomly assigned to a low-intensity (50% 1-RM) or moderate-intensity (75% 1-RM) RT group and divided into pre-menopausal and post-menopausal according to their hormone profile. Fat-free mass (FFM), MM, fat mass (FM), muscle thickness (Vastus lateralis (VL), Rectus femoris (RF), Triceps brachii (TB)), grip strength, 1-RM squat and bench press were assessed before and after each phase. Statistical analysis was performed using a linear mixed model to account for fixed (time and group) and random (individual) effects. RESULTS: A total of 31 women successfully completed the study. No injuries occurred during the intervention. Significant increases in 1-RM squat and bench press were observed in all groups. No interaction effect was observed for the strength parameters. In pre-menopausal women, FFM, MM and RF muscle thickness increased significantly, while VL showed a trend. These effects were not present in post-menopausal women regardless of RT intensity. CONCLUSION: RT with free weight is safe and effective for middle-aged women to increase 1-RM. Hypertrophy effects were found exclusively in pre-menopausal women. To achieve hypertrophy and/or body composition changes in post-menopausal women, larger training volumes (> 6-8 sets/muscle per week) are likely required.


Subject(s)
Muscle Strength , Resistance Training , Middle Aged , Humans , Female , Muscle Strength/physiology , Muscle, Skeletal/physiology , Body Composition , Menopause , Hypertrophy
5.
PLoS One ; 18(4): e0284216, 2023.
Article in English | MEDLINE | ID: mdl-37053143

ABSTRACT

BACKGROUND: Women are underrepresented in resistance exercise-related studies. To date only one meta-analysis provides concrete training recommendations for muscle strength gains through resistance training in eumenorrhoeic women. OBJECTIVE: This review aims to identify research gaps to advance future study in this area to expand the knowledge concerning resistance exercise-induced strength gains in women and to provide guidelines on the number of repetitions per set and the training frequency per week to enhance maximal muscle strength. METHODS: The electronic databases PubMed and Web of Science were searched using a comprehensive list of relevant terms. After checking for exclusion criteria, 31 studies could be included in the final analysis using data from 621 subjects. From these data sets, the ideal number of repetitions per set and also the training frequency per week were analyzed. RESULTS: In the lower body, the largest gains were achieved with 1 to 6 repetitions (17.4% 1RM increase). For lower-body exercises, the highest gains were achieved with 13 to 20 repetitions (8.7% 1RM increase). The lower body should be trained two times a week (8.5% 1RM increase). The upper body should be trained two (5.2% 1RM increase) to three times (4.5% 1RM increase) a week. CONCLUSION: Women can increase their 1RM by 7.2% per week in the upper body and by 5.2% per week in the lower-body exercises. The upper body can be trained more than two times per week whereas the lower body should be trained two times. Women with intermediate experiences in RT and advanced performance level show more rapid increases in strength in the lower-body compared to the upper-body while no differences were found between upper and lower limb adaptations in RT-beginner subjects.


Subject(s)
Resistance Training , Humans , Female , Muscle, Skeletal/physiology , Muscle Strength/physiology , Exercise , Adaptation, Physiological
6.
Article in English | MEDLINE | ID: mdl-36767221

ABSTRACT

Over the past few years, the number of people who have avoided animal products has been rising steadily. A plant-based diet is associated with a healthier lifestyle and has positive effects on various diseases. More and more healthy active people and performance-orientated athletes are giving up animal products for various reasons, such as for an improved performance or faster regeneration. However, the data in this context are limited. This study aimed to obtain initial findings on the influence of a diet change to veganism on the performance of strength-trained individuals. For this study, a total of 15 omnivorous individuals were recruited. They documented their dietary food intakes over 16 weeks. Every four weeks, the strength performance was tested via a leg press and bench press. In the first 8 weeks, the participants maintained their omnivorous diet, followed by 8 weeks of a vegan dietary phase. In total, 10 subjects participated successfully, and their data were part of the statistical analyses. There was no difference in the absolute and relative strength performance for the leg and bench press after changing to a vegan diet. For the total calorie intake and carbohydrates, only a small treatment effect, but no time effect, was observed. However, for the protein intake, a time and group effect were detected. In addition, the relative protein intake decreased significantly and was lower than the current recommendations for athletes. The results demonstrate that a change to a vegan diet has no beneficial nor negative effect on the strength performance when the total calorie intake and carbohydrate content are covered in the first 8 weeks.


Subject(s)
Diet, Vegan , Diet , Animals , Humans , Pilot Projects , Energy Intake , Vegans
8.
Nutrients ; 13(9)2021 Sep 06.
Article in English | MEDLINE | ID: mdl-34578999

ABSTRACT

The number of people suffering from being overweight or obese has risen steadily in recent years. Consequently, new forms of nutrition and diets were developed as potential solutions. In the last years, the time-restricted feeding and continuous energy restriction via macronutrient-based diets were increasingly popular. Both diets were exclusively studied separately. A comparison of the two diets for people with a high body mass index despite regular physical activity has not yet been studied in detail. Therefore, this study aimed to compare the effects of these two diets on body composition and adherence. For this study, a total of 42 subjects (m = 21, f = 21) with a BMI above 25 were recruited from a local fitness gym. After a two-week familiarisation period, one of the two diets was followed over 14 weeks. Dietary behaviour was monitored throughout the period with a food diary. The primary measurement parameters were body weight, lean body mass, fat mass, body mass index, and waist and hip circumference. In addition, adherence was assessed and calculated by food diary and questionnaire. In total, the data of 35 participants (m = 14, f = 21) were analysed. Significant reductions in body weight, fat mass, body mass index, and waist and hip circumference were observed in both groups (p < 0.05). No significant change could be observed in lean body mass in either category. No group and gender differences were detected in any of the primary parameters. For the secondary parameters, a significantly higher adherence was observed in the time-restricted feeding group (p < 0.05). In addition, it can be assumed that an adherence of 60-70% cannot lead to positive changes in body composition. In conclusion, there were no differences between the two diets on the primary parameters. However, it seemed that time-restricted feeding can be better implemented in everyday life, and an adherence of more than 70% is required for both diets to prove effective.


Subject(s)
Body Composition , Exercise , Fasting , Nutrients/administration & dosage , Obesity/diet therapy , Adult , Body Mass Index , Diet Surveys , Diet, Reducing , Female , Humans , Male , Nutritional Status , Overweight/diet therapy , Young Adult
9.
Int J Exerc Sci ; 14(1): 187-201, 2021.
Article in English | MEDLINE | ID: mdl-34055137

ABSTRACT

The purpose of the study was to compare the normalized-electromyographic (NEMG) activity of the gluteus maximus (GMAX), gluteus medius (GMED), biceps femoris (BF) and erector spinae (ES) muscles during the single-leg deadlift (SLDL) and the conventional-deadlift (DL). Additionally, a potential influence of body height on the NEMG activity was examined. Fifteen training-experienced male subjects completed the study. SLDL showed significantly higher average concentric NEMG values of the GMED (77.6% vs. 59.3% [p = 0.002, ES = 1.0]) and BF (82.1% vs. 74.2% [p = 0.041, ES = 0.6]). Significantly lower NEMG levels were found only in the left strand of the ES muscle (67.2% vs. 82.7% [p = 0.004, ES = 0.9]). A significant influence of body height on EMG activity was also observed for all muscles, with the exception of the GMED, during the SLDL. Body height correlated negatively with the concentric EMG activity of the ES (r = -0.54 to -0.58), the BF (r = -0.63) and the GMAX (r = -0.85). In the DL there was a negative correlation only in the BF (r = -0.59) and the GMAX (r = -0.7). This means that subjects with a lower body height showed a higher NEMG activity in corresponding muscles. The results of this study indicate that the SLDL is preferable to the DL in training the BF, and GMED. In addition, coaches should be aware that athletes body height can influence the extent to which the respective muscles are activated.

10.
PLoS One ; 15(6): e0235377, 2020.
Article in English | MEDLINE | ID: mdl-32603351

ABSTRACT

The purpose of this study was to investigate whether a six-week, twice weekly resistance training (4 sets at 30% 1-RM until failure) with practical blood flow restriction (BFR) using 7cm wide cuffs with a twist lock placed below the patella is superior to training without BFR (NoBFR) concerning muscle mass and strength gains in calf muscles. A two-group (BFR n = 12, mean age 27.33 (7.0) years, training experience 7.3 (7.0) years; NoBFR n = 9, mean age 28.9 (7.4) years, training experience 7.1 (6.6) years) randomized matched pair design based on initial 1-RM was used to assess the effects on structural and functional adaptations in healthy males (Perometer calf volume [CV], gastrocnemius muscle thickness using ultrasound [MT], 7-maximal hopping test for leg stiffness [LS], 1-RM smith machine calf raise [1-RM], and visual analogue scale as a measure of pain intensity [VAS]). The mean number of repetitions completed per training session across the intervention period was higher in the NoBFR group compared to the BFR group (70 (16) vs. 52 (9), p = 0.002). VAS measured during the first session increased similarly in both groups from first to fourth set (p<0.001). No group effects or time×group interactions were found for CV, MT, LS, and 1-RM. However, there were significant time effects for MT (BFR +0.07 cm; NoBFR +0.04; p = 0.008), and 1-RM (BFR +40 kg; NoBFR +34 kg; p<0.001). LS and CV remained unchanged through training. VAS in both groups were similar, and BFR and NoBFR were equally effective for increasing 1-RM and MT in trained males. However, BFR was more time efficient, due to lesser repetition per training session.


Subject(s)
Adaptation, Physiological , Muscle Strength/physiology , Regional Blood Flow/physiology , Adult , Humans , Male , Muscle, Skeletal/physiology , Resistance Training/methods , Young Adult
11.
Int J Exerc Sci ; 13(6): 633-644, 2020.
Article in English | MEDLINE | ID: mdl-32509134

ABSTRACT

The purpose of this study was to examine the effects of detraining following a block (BLOCK) or daily undulating periodized (DUP) resistance training (RT) on hypertrophy, strength, and athletic performance in adolescent athletes. Twenty-one males (age = 16 ± 0.7 years; range 15-18 years) were randomly assigned to one of two 12-week intervention groups (three full-body RT sessions per week): BLOCK (n = 9); DUP (n = 12). Subsequently a three-week detraining period was applied. Body mass, fat mass (FM), fat-free mass (FFM), muscle mass, muscle thickness (rectus femoris, vastus lateralis and triceps brachii), one-repetition maximum squat and bench press, countermovement jump (CMJ), peak power calculated from CMJ (Ppeak), medicine ball put distance, and 36.58m sprint were recorded before and after RT as well as after detraining. BLOCK and DUP were equally effective for improvements of athletic performance in young athletes. Both groups displayed significantly (ρ ≤ 0.05) higher values of all measures after RT except FM, which was unchanged. Only FM increased (p = 0.010; ES = 0.14) and FFM decreased (p = 0.018; ES = -0.18) after detraining. All other measurements were unaffected by the complete cessation of training. Values were still elevated compared to pre-training. Linear regression showed a strong correlation between the percentage change by resistance training and the decrease during detraining for CMJ (R2 = 0.472) and MBP (R2 = 0.629). BLOCK and DUP RT seem to be equally effective in adolescent athletes for increasing strength, muscle mass, and sport performance. In addition, three weeks of detraining did not affect muscle thickness, strength, or sport performance in adolescent athletes independent of previous resistance training periodization model used.

12.
J Sports Med Phys Fitness ; 59(6): 1030-1035, 2019 Jun.
Article in English | MEDLINE | ID: mdl-31204454

ABSTRACT

BACKGROUND: The aim of this study was to identify the acute hormonal responses of salivary testosterone (T) and cortisol (C) concentrations during and after two different resistance exercises involving the lower and the upper body, respectively. METHODS: For this reason, 13 healthy recreationally trained male athletes performed an identical strength protocol (5x10 reps, with ~75% of 1 RM) with the exercises bench press and back-squat in a cross-over design. Saliva samples were taken at baseline (t0), mid training (t1), immediately after (t2), 15 (t3) and 45 minutes after the training (t4). Samples were analyzed for T and C, and the T/C ratio was calculated. RESULTS: T concentrations increased significantly from t0 to t2, t3 and t4 and also at t3 and t4 for C in the back-squat protocol (P<0.05). There were no significant changes for T and C in the bench press protocol (P<0.05). The T/C ratio remained constant for the bench press protocol. The T/C ratio increased in the squat protocol at t2 and decreased at t3 and t4. CONCLUSIONS: We conclude that back-squat exercise can change the hormonal state of the body after an intense resistance training workout, while an exercise with a lower amount of muscle mass (i.e. bench press) has almost no influence on T and C.


Subject(s)
Hydrocortisone/analysis , Resistance Training , Saliva/chemistry , Testosterone/analysis , Adult , Athletes , Cross-Over Studies , Humans , Male , Young Adult
13.
Int J Sports Physiol Perform ; 14(6): 814­821, 2019 07 01.
Article in English | MEDLINE | ID: mdl-30569761

ABSTRACT

Purpose: Muscle mass, strength, and power are important factors for performance. To improve these characteristics, periodized resistance training is used. However, there is no consensus regarding the most effective periodization model. Therefore, the purpose of this study was to compare the effects of block (BLOCK) vs daily undulating periodization (DUP) on body composition, hypertrophy, strength, performance, and power in adolescent American football players. Methods: A total of 47 subjects participated in this study (mean [SD] age = 17 [0.8] y, strength training experience = 0.93 [0.99] y). Premeasurements and postmeasurements consisted of body mass (BM); fat mass; relative fat mass; fat-free mass (FFM); muscle mass (MM); muscle thickness of the vastus lateralis (VL), rectus femoris (RF), and triceps brachii (TB); 1-repetition-maximum back squat (BS) and bench press (BP); countermovement jump (CMJ); estimated peak power (Wpeak) from vertical jump performance; medicine-ball put (MBP); and 40-yd sprint. Subjects were randomly assigned in either the BLOCK or DUP group prior to the 12-wk intervention period consisting of 3 full-body sessions per week. Results: Both groups displayed significantly higher BM (P < .001), FFM (P < .001), MM (P < .001), RF (P < .001), VL (P < .001), TB (P < .001), BS (P < .001), BP (P < .001), CMJ (P < .001), Wpeak (P < .001), and MBP (P < .001) and significantly lower sprint times (P < .001) after 12 wk of resistance training, with no difference between groups. Conclusions: Resistance training was effective to increase muscle mass, strength, power, and performance in adolescent athletes. BLOCK and DUP affect anthropometric measures and physical performance equally.


Subject(s)
Football , Muscle Strength , Periodicity , Resistance Training/methods , Adolescent , Athletic Performance/physiology , Body Composition , Humans , Male , Muscle, Skeletal/physiology
14.
J Strength Cond Res ; 25(9): 2598-604, 2011 Sep.
Article in English | MEDLINE | ID: mdl-21869634

ABSTRACT

People who are afflicted with "metabolic syndrome" exhibit multiple coronary disease risk factors such as insulin resistance, hypertension, hyperlipidemia, or obesity. Twenty-six volunteers (13 women and 13 men) with such disease risk factors (56 ± 5 years) participated in a 14-week resistance training program. Given the fact that resistance training may improve cardiometabolic parameters, the fasting total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides, insulin, glucose value, homeostatic model assessment (HOMA) index, and blood pressure and body mass index (BMI) were measured before and after the training intervention. In addition, muscle biopsies from the vastus lateralis muscle of 11 of the men and 5 of the women were analyzed to determine whether changes in the muscle morphology influence the cardiometabolic parameters. Resistance training resulted in a significant increase in fasting HDL for the entire group (from 44.35 ± 9.43 to 48.57 ± 10.96 mg·dl(-1), p = 0.016). No other blood parameter changed significantly. No change was observed in the HOMA index, blood pressure, or BMI. The muscle fiber type distribution did not change, but a significant hypertrophy of muscle fibers was evident (an increase of the ellipse minor axis of 67.3 ± 16.6 to 72.1 ± 12.3 µm, p = 0.004). Moderate intensity resistance training, as was performed in our study, induces hypertrophic impulses but does not seem to have a clear positive influence on cardiometabolic risk factors. However, 2 sessions of moderate intensity resistance training per week can enhance the fasting HDL cholesterol in middle-aged subjects.


Subject(s)
Metabolic Syndrome/physiopathology , Muscle, Skeletal/physiopathology , Resistance Training , Blood Glucose/physiology , Blood Pressure/physiology , Body Mass Index , Cholesterol/blood , Cholesterol/physiology , Exercise Therapy , Female , Homeostasis/physiology , Humans , Insulin/blood , Insulin/physiology , Lipoproteins, HDL/physiology , Lipoproteins, LDL/physiology , Male , Middle Aged , Organ Size/physiology , Triglycerides/blood , Triglycerides/physiology
15.
Mol Cell Endocrinol ; 330(1-2): 1-9, 2010 Dec 15.
Article in English | MEDLINE | ID: mdl-20801187

ABSTRACT

Myostatin propeptide (MYOPRO) and follistatin (FOLLI) are potent myostatin inhibitors. In this study we analysed effects of training and androgens on MYOPRO and FOLLI concentrations in blood and skeletal muscle using Immuno PCR. Young healthy males performed either a 3-month endurance training or a strength training. Blood and biopsy samples were analysed. Training did not significantly affect MYOPRO and FOLLI concentrations in serum and muscle. To investigate whether total skeletal muscle mass may affect circulating MYOPRO and FOLLI levels, blood samples of tetraplegic patients, untrained volunteers and bodybuilders were analysed. MYOPRO was significantly increased exclusively in the bodybuilder group. In orchiectomised rats MYOPRO increased in blood and muscle after treatment with testosterone. In summary our data demonstrate that moderate training does not affect the concentrations of MYOPRO to FOLLI. In contrast androgen treatment results in a significant increase of MYOPRO in skeletal muscle and serum.


Subject(s)
Androgens/pharmacology , Follistatin/blood , Muscle, Skeletal/metabolism , Myostatin/blood , Physical Education and Training , Polymerase Chain Reaction/methods , Protein Precursors/blood , Animals , Biopsy , Blotting, Western , Follistatin/immunology , Humans , Male , Muscle, Skeletal/drug effects , Muscle, Skeletal/pathology , Myostatin/immunology , Orchiectomy , Organ Size/drug effects , Physical Conditioning, Animal , Protein Precursors/immunology , Rats , Rats, Wistar , Testosterone/pharmacology , Young Adult
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