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1.
Neurourol Urodyn ; 37(4): 1365-1371, 2018 04.
Article in English | MEDLINE | ID: mdl-29130524

ABSTRACT

AIMS: The Patient Global Index of Severity (PGI-S) and the Patient Global Index of Improvement (PGI-I) are global impression questionnaires developed in English and validated in women with stress urinary incontinence (SUI). This validation study tested the psychometric properties of German-language versions of the two questionnaires in German-speaking women with SUI. METHODS: The German-language PGI-S and PGI-I were psychometrically tested and validated using the SF-12 questionnaire, the Kinǵs Health Questionnaire (KHQ), clinical parameters, incontinence episode frequency and pad use in 311 patients before and 3 months after receiving a TVT-O or TVT tape for SUI. RESULTS: At baseline and 3 months postoperatively there was a positive correlation between PGI-S response categories and clinical parameters, IEF and pad use, and nearly all KHQ subscales. There were no correlations between response categories of PGI-S at baseline and PGI-I at 3 months and the SF-12 scales PCS-12 and MCS-12. CONCLUSION: Our results demonstrated good psychometric properties of the German-language PGI-S and PGI in German-speaking women with SUI.


Subject(s)
Quality of Life , Surveys and Questionnaires , Urinary Incontinence, Stress/diagnosis , Adult , Aged , Aged, 80 and over , Austria , Female , Humans , Middle Aged , Psychometrics , Translations , Treatment Outcome
2.
Int Urogynecol J ; 27(8): 1235-44, 2016 Aug.
Article in English | MEDLINE | ID: mdl-26883366

ABSTRACT

INTRODUCTION AND HYPOTHESIS: Condition-specific sexual questionnaires are essential for clinical trials and important patient-reported outcome measures. The aim of the study was to translate the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire-International Urogynecology Association Revised (PISQ-IR) into German and to clinically validate it in a German-speaking population. METHODS: The translated PISQ-IR was linguistically validated in two rounds of cognitive interviews. The final instrument was psychometrically validated in women presenting to urogynecological clinics with pelvic floor dysfunction. For analysis of criterion validity, three related self-reported measures were administered: the Female Sexual Function Index (FSFI), the Kings Health Questionnaire (KHQ), and the 36-Item Short Form Health Survey (SF-36). For external validity, PISQ-IR subscales were compared to the clinical-measures Pelvic Organ Prolapse Quantification system (POP-Q) stage, pelvic floor muscle tone, and Oxford Grading Scale. Descriptive statistics, floor and ceiling effects, internal consistency using Cronbach's alpha coefficient, and Pearson correlations were calculated for all PISQ-IR subscales. RESULTS: The PISQ-IR was completed by 197 women, out of whom 66 (33.5 %) considered themselves not sexually active (NSA) and 131 (66.5 %) as sexually active (SA). Participants' mean age was 57 ± 12 years; 50 % were diagnosed with symptomatic POP, 74 % with urinary incontinence (UI) and 4 % with anal incontinence (AI). The PISQ-IR subscales were analyzed separately for SA and NSA women with Cronbach's alpha coefficients ranging from 0.64 to 0.94. Moderate to high correlations were observed between PISQ-IR subscales and related quality of life (QoL) scales and corresponding FSFI scales. CONCLUSION: Initial testing of the German PISQ-IR suggests it is an internally consistent and valid tool for use in clinical practice and research.


Subject(s)
Pelvic Organ Prolapse/psychology , Sexual Behavior/psychology , Sexual Dysfunction, Physiological/psychology , Surveys and Questionnaires/standards , Translations , Urinary Incontinence/psychology , Aged , Fecal Incontinence/psychology , Female , Germany , Humans , Middle Aged , Psychometrics , Quality of Life , Reproducibility of Results
3.
Patholog Res Int ; 2010: 608519, 2010.
Article in English | MEDLINE | ID: mdl-21151512

ABSTRACT

Undifferentiated endometrial sarcomas (UESs) of the ovary are very rare tumors. This paper presents a case of a 56-year-old patient with a history of hysterectomy and bilateral salpingectomy seven years ago for uterine leiomyomata. Intraoperatively, a tumor originating from the left ovary, adherent to the sigmoid colon, with infiltration of the small intestine and the vaginal apex was found. Histologically, the tumor was composed of pleomorphic round and oval to spindled cells with polymorphous vesicular nuclei with coarse chromatin and large nucleoli. Mitotic activity was brisk. There were large necrotic areas. Adjacent to the tumor tissue endometrium-like glands surrounded by fibrous stroma with macrophages corresponding to ovarian endometriosis were noted. Tumor cells showed diffuse strong immunoreactivity for vimentin and patchy strong staining for CD10; no reactivities were found for AE1/AE3, desmin, S-100, LCA, CD20, c-kit, and CD31. The patient died of her neoplastic disease four months postoperatively. CD10 is frequently expressed in different gynecopathological as well as other lesions, and, thus, nonspecific without relevance to the classification of this case. Morphological features, extensive sampling, and appropriate immunohistochemistry including markers for cytokeratins and myogenic differentiation are mandatory to arrive at the correct diagnosis.

4.
Int Urogynecol J ; 21(3): 299-302, 2010 Mar.
Article in English | MEDLINE | ID: mdl-19936593

ABSTRACT

INTRODUCTION AND HYPOTHESIS: We tried to estimate the frequency of surgery for posthysterectomy vault prolapse. METHODS: We contacted all 86 departments of gynecology in Austria and asked them about total number of hysterectomies and total number of operations for vault prolapse. We then calculated a percentage of patients undergoing surgery for posthysterectomy vault prolapse. RESULTS: Sixty-five of 86 public hospitals replied (response rate 76%) and reported a total of 7,645 hysterectomies and 577 operations for vault prolapse for the year 2005, giving a percentage of 7.16 for surgery for posthysterectomy vault prolapse. On the assumption that vault prolapse takes on the average 10 years to develop and that the number of hysterectomies decreased by 10% over 10 years, we calculated a modified frequency of 6.52%. CONCLUSIONS: We were able to calculate an estimation of the frequency for posthysterectomy vault prolapse requiring surgical repair between 6% and 8%.


Subject(s)
Hysterectomy/adverse effects , Hysterectomy/statistics & numerical data , Pelvic Organ Prolapse/etiology , Austria/epidemiology , Female , Gynecologic Surgical Procedures/statistics & numerical data , Humans , Pelvic Organ Prolapse/epidemiology
5.
Int Urogynecol J Pelvic Floor Dysfunct ; 18(9): 1003-5, 2007 Sep.
Article in English | MEDLINE | ID: mdl-17219254

ABSTRACT

The pelvic organ prolapse quantification (POPQ) system is currently the most common and specific system describing different prolapse stages. Nevertheless, its use is not yet accepted worldwide in routine care. Our aim was to develop a simple teaching tool for the POPQ system capable of simulating different stages of uterovaginal prolapse for use in medical education with hands on training. We constructed a moveable and flexible tool with an inverted Santa Claus' cap, which simulated the vaginal cuff and the tassel at the end representing the cervix. A wooden embroidery frame fixed the cap and served as the hymen, the reference point for all measurements. Inside the cap, we sewed buttons to define the anatomic landmark points Aa and Ap located 3 cm distal from the frame. After explaining the device to the students, we used the three-by-three grid for recording the quantitative description of the pelvic organ support. First, each student had to demonstrate a specific prolapse with his cap device. Then, a prolapse was simulated on the cap, and the student had to take the relevant measurements and record them in the POPQ grid. The main training effect to understand the POPQ system seems to be the possibility for each trainee to simulate a three-dimensional prolapse with this flexible vagina model.


Subject(s)
Gynecology/education , Models, Anatomic , Uterine Prolapse/pathology , Disease Progression , Female , Humans , India , Pelvis/pathology , Uterine Prolapse/classification
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