ABSTRACT
Five previously unreported cases of congenital epulis of the newborn are presented. All five cases were on the anterior maxillary alveolar ridge. Four were removed at 2 days of age and one at 7 weeks. Light microscopy demonstrated large eosinophilic granular cells within vascular fibrous connective tissue. Immunohistochemical studies revealed a positivity for vimentin and neuron specific enolase. Cytogenetic evaluation performed on one case was normal. Estrogen and progesterone receptors were absent in the one case so studied. Electron microscopy demonstrated tumor cells that were filled with autophagosomes. Cellular organelles were significantly reduced and inversely related to the number of cytoplasmic autophagosomes. Many of the autophagosomes contained collagen precursors. Poorly formed junctional complexes were seen. Occasional tumor cells demonstrated long processes that contained contractile microfilaments, pinocytosis, and areas of exocytosis. These studies suggest the tumor cells represent early mesodermal cells that express pericytic and myofibroblastic features that undergo cytoplasmic autophagocytosis.
Subject(s)
Gingival Neoplasms/congenital , Gingival Neoplasms/pathology , Granular Cell Tumor/congenital , Granular Cell Tumor/pathology , Collagen/analysis , Female , Gingival Neoplasms/chemistry , Granular Cell Tumor/chemistry , Histocytochemistry , Humans , Infant , Infant, Newborn , Sex RatioABSTRACT
We present an example of an intraoral benign solid oncocytoma of minor salivary gland origin. A review of intraoral benign solid oncocytomas reported in the English-language literature and discussion of the clinical behavior of these tumors are included.
Subject(s)
Adenoma/pathology , Salivary Gland Neoplasms/pathology , Salivary Glands, Minor/pathology , Salivary Glands/pathology , Aged , Humans , MaleABSTRACT
Two examples of an unusual presentation of oropharyngeal candidiasis in cancer patients are offered. The light and scanning electron microscopic appearances of candidiasis involving the dentin of teeth are described. The potential significance of recognition of this form of candidiasis in cancer patients is discussed.
Subject(s)
Candidiasis, Oral/pathology , Dentin/microbiology , Leukemia, Myeloid, Acute , Parotid Neoplasms , Adenoma, Pleomorphic/radiotherapy , Aged , Candida albicans/isolation & purification , Candidiasis, Oral/microbiology , Child, Preschool , Dentin/pathology , Humans , Leukemia, Myeloid, Acute/drug therapy , Male , Parotid Neoplasms/radiotherapy , Tooth Diseases/microbiology , Tooth Diseases/pathology , Tooth, Deciduous/microbiology , Tooth, Deciduous/pathologyABSTRACT
A case of chondromyxoid fibroma of the anterior maxilla is presented. The light and electron microscopic appearances of this tumor are described. A review of chondromyxoid fibromas of the jaws is performed, with a discussion of the appropriate therapy.
Subject(s)
Chondroma/ultrastructure , Maxillary Neoplasms/ultrastructure , Adult , Chondroma/pathology , Chondroma/therapy , Female , Humans , Jaw Neoplasms/pathology , Jaw Neoplasms/therapy , Maxillary Neoplasms/pathology , Maxillary Neoplasms/therapySubject(s)
Perfusion , Renal Dialysis , Urea/poisoning , Charcoal , Humans , Perfusion/adverse effects , Thrombocytopenia/etiology , Urea/bloodABSTRACT
It has been demonstrated with an in vitro model that hemoperfusion through Amberlite XAD4 or coated charcoal containing cartridges eliminates carbromal and its ureid derivatives more efficiently than hemodialysis. The following clearancs were measured in vitro (blood flow: 200 ml/min): Coil dialyser (1 m2): 55-85 ml/min, charcoal hemoperfusion 100-125 ml/min, Amberlite XAD4 hemoperfusion: 200 ml/min. The data of one patient who had been hemoperfused after the ingestion of 35 g Carbromal with the Haemocol cartridge (SMith & Nephews) are depicted. Our results permit to draw the conclusion that hemoperfusion at this time is the most efficient means to eliminate Carbromal from intoxicated patients.
