[Antigenic characteristics of immunoglobulin preparations]. / Antigennaia kharakteristika preparatov immunoglobulinov.

A comparative study of the content of serum protein antigens in 156 batches of human immunoglobulin preparations, produced from placental material and donor plasma in the USSR and Bulgaria, has been made by means of immune electrophoresis. The results thus obtained indicate that immunoelectrophoretic analysis may be used for the additional characteristic of the antigenic structure of immunoglobulin preparations, as well as for evaluating the degree of the purification of immunoglobulin from nonspecific serum proteins in the process of the production of commercial preparations.

[Gonadotropic activity of the immunoglobulins from placental, abortion and donor blood]. / Gonadotropnaia aktivnost' immunoglobulinov iz platsentarnoi, abortnoi i donorskoi krovi.

Gonadotropic activity of 106 series of immunoglobulin preparations obtained in the USSR and-the People's Republic of Bulgaria was studied. In difference from donor immunoglobulins, all the preparations of placental materials were contaminated with chorionic gonadotropin. Gonadotropin content in the immunoglobulins made of abortion serum was 2--7 times greater than in the preparations from the retoplacental serum and the placental extracts. The mean results of gonadotropin content in the immunoglobulins obtained by biological studies differed from those obtained from the investigations by immunological methods since the mentioned methods apparently characterized different properties of the hormonal molecule.

[Comparative study of the content of blood group substances A and B in immunoglobulins prepared from placental and donor sera]. / Sravnitel'noe izuchenie soderzhaniia gruppovykh substantsii krovi A i B v immunoglobulinakh, izgotovlennykh iz platsentarnykh i donorskikh syvorotok.

Blood group specific substances A and B were revealed in all the samples of immunoglobulin commercial preparations made in the USSR, Bulgaria, and India from the retroplacental, abortion sera, and from the placental extract. Their content varied in different batches of the preparations--from 8 to 64 microgram/ml of substance A, and from 6 to 256 microgram/ml of substance B. In the majority of immunoglobulin batches prepared from donor sera no group-specific blood substances A and B were revealed; only in 3 of 14 batches was there revealed substance A in the amount of 3 microgram/ml.