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Article in German | MEDLINE | ID: mdl-6169609

ABSTRACT

The relative reticulocyte content and the average Fe-uptake of peripheral reticulocytes were investigated in rats after a blood loss and whole body irradiation as well after a combined treatment for a time of 15 days. The acute loss of blood caused a rapid increase of cellular uptake within 24 hours, whereas after irradiation a considerable diminution could be observed. In addition to a direct stimulation or inhibition a considerable diminution could be observed. In addition to a direct stimulation or inhibition of bone-marrow activity a direct impact of reticulocytes by blood loss and irradiation is discussed.


Subject(s)
Blood Volume , Bone Marrow/radiation effects , Reticulocytes/radiation effects , Animals , Dose-Response Relationship, Radiation , Erythrocyte Count , Female , Iron/metabolism , Male , Rats , Rats, Inbred Strains , Reticulocytes/metabolism , Whole-Body Irradiation
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