[Features of hemocoagulation potential, antithrombogenic properties of the vascular wall and platelet functional activity in workers of an expeditionary team]. / Osobennosti gemokoaguliatsionnogo potentsiala, antitrombogennykh svoistv sosudistoi stenki i funktsional'noi aktivnosti trombotsitov u rabochikhékspeditsionno-vakhtovykh brigad.

Hemostasis was studied in 373 oilmen aged 20-40 working according to expedition schedules. Control subjects were not engaged in expeditions. Expedition labor was found to cause hypercoagulemia with parallel decline in anticoagulant activity. Vascular wall ability to release anticoagulants and fibrinolysis activators in the blood stream appeared inhibited. Platelet count in the peripheral blood, platelet aggregation, platelet factor III activity were increased. The duration of expedition service and phases of working cycle seem to affect hemostatic parameters.

The role of the heart in the mechanism modifying the functional state of the blood clotting and fibrinolytic systems in thyroxine toxicosis.

In 36 rabbits the role of the heart in the genesis of changes in the tissue components of blood clotting and fibrinolysis in thyroxine toxicosis was studied. It was found that on the 5th and 10th days of toxicosis the thromboplastic (P = 0.002) an anticoagulant (P less than 0.001) myocardial activities decreased, and on the 15th day, increased. On the 20th day the myocardial thromboplastic activity remained increased, whereas the anticoagulant activity was further sinking (P = 0.05). Simultaneously the total fibrinolytic activity in the blood flowing through the heart and in myocardial extract increased (P less than 0.001), and the antiplasmin activity decreased.