[Invasive aspergillosis in patients who died from acute leukemia]. / Invazivna aspergiloza u pochinali s ostra levkoza.

The necropsy material with acute leukosis (166 deceased) was studied in order to establish the incidence of invasive aspergillosis. It was established in 16 of the deceased (9,64%): aspergillosis pneumonia--in 5 cases, aspergillosis sepsis--in II, with invasion of lungs, brain, spleen, liver, myocardium and other organs. Clinically aspergillosis was not distinguished. Continuous septic temperature, not influenced by antibiotic therapy should draw the attention to the presence of aspergillosis. The factors, preconditioning aspergillosis infection are stressed upon: immune-suppressive treatment in acute leukosis, granulocytopenia, continuous preceding antibiotic therapy, etc. The difficulties in the clinical differentiation of the infection are emphasized. With a view to the high incidence and lethality of aspergillosis in acute leukosis, the introduction of modern diagnostic methods and treatment are underlined to be necessary.

[Thrombotic thrombocytopenic purpura (Moschkowitz's disease)--a review of the literature with a case report]. / Trombotichna trombotsitopenichna purpura (bolest na Moshkovits)--pregled na literaturata s opisanie na edin sluchai.

A case with thrombotic thrombocytopenic purpura (TTP) in a young female is described. The clinical picture is described as well as the pathologoanatomical finding, the characteristic and pathognomonic sins of the disease being mentioned. A survey of the literature is made, covering data about the thorough characteristic of the disease--clinical-laboratory, pathomorphological picture, etiological and pathogenetic aspects. Attention is paid to the laboratory discrepancies with the syndrome of disseminated intravascular coagulation, included in the differential diagnosis when making the clinical diagnosis of TTP. The success in the treatment of TTP during the last several years is reported with the introduction of combined therapy with corticosteroids, splenectomy, antiaggregating thrombocyte agents, exsanguination transfusion and, with the most reliable effect for the present--plasmapheresis and plasmainfusions.

[Case of an unusual initial localization of a malignant lymphoblastic lymphoma]. / Sluchai s neobichaina nachalna lokalizatsiia na limfoblsten malignen limfom.

A case is presented with lymphosarcoma and generalization of the process, with an atypical initial localization of the tumour in the gluteal regions. The grounds for admittance of the extranodal origination is the rather long period of time (10 months) after the initial manifestation of the tumour till the following generalization, accompanied by a deterioration of the patient's state.