[Effects of selective proximal vagotomy on gastrin, glucagon and insulin contents in blood of patients with duodenal ulcer]. / Vliianie selektivnoi proksimal'noi vagotomii na soderzhanie gastrina, gliukagona i insulina v krovi bol'nykh s iazvoi dvenadtsatisperstnoi kishki.

Content of gastrin, glucagon and insulin in the blood of 49 patients with a duodenal ulcer was similar to that in control group patients. Significant increase in gastrin and glucagon levels, decrease in insulin content was noted 14-15 days after the performance of selective proximal vagotomy. At the late period, concentration of the hormones studied was within the limits of physiologic levels. The data obtained permit to assess the completeness of vagotomy and to predict the long-term result of the operation.

[Tactics of the treatment of acute pancreatitis]. / Taktika lecheniia ostrogo pankreatita.

During the period of 6 years 176 patients with an acute pancreatitis were treated in the clinic, 17 (9,1%) of whom with destructive forms of disease. Tactics of treatment was developed on the grounds of ultrasonographic scanning of pancreas data, laparoscopy and enzymologic investigation results. Twenty two (12,5%) of patients were operated on. Postoperative lethality was 22,7%. Erosive hemorrhage was the cause of death in 2 patients and septic-purulent complications--in 3.

[Morphological changes and function of gastric and pancreatic mucosa after selective proximal vagotomy in patients with pyloroduodenal ulcer]. / Morfologicheskie izmeneniia i funktsionalnoe sostoianie slizistoi obolochki zheludka i podzheludochnoi zhelezy posle selektivnoi proksimalnoi vagotomii u bolnykh s piloroduodenalnoi iazvoi.

The pathomorphological changes in the gastric mucosa and acid production were studied in 118 patients with ulcer disease of a pyloric portion of the stomach and duodenum before and after selective proximal vagotomy in combination with drainage operation. Before the operation, the atrophic changes were the most pronounced in the gastric antrum. Increase in debit of chlorohydric acid was caused by increase in the volume of gastric juice and acid production. Stimulation with food contributes to considerable increase in gastrin concentration in the blood of the patients in low level of glucagon and insulin. Early after the operation, the signs of acute inflammation were revealed in the mucosa of the body and antrum. In increase of a basal level of gastrin and glucagon, acid production significantly decreased. Long-term atrophic gastritis of the body of a stomach was noted mainly in patients with delayed evacuation of its contents. Normalization of the level of hormones correlated with the indices of acid-producing function of the stomach.