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Eur J Epidemiol ; 14(2): 117-23, 1998 Feb.
Article in English | MEDLINE | ID: mdl-9556169

ABSTRACT

In 1986, a 26% seroprevalence of IgG- anti-Borrelia burgdorferi antibodies was observed among 950 orienteers and the incidence of new clinical infections was 0.8%. In 1993, a total of 305 seropositive orienteers were reexamined. During that time, 15 cases (4.9%) of definite/probable Lyme disease occurred in this seropositive group (12 skin manifestations and 3 monoarticular joint manifestations). Among the 12 definite cases, 9 showed new clinical infections (7 EM, 1 acrodermatitis chronica atrophicans, 1 arthritis), and 3 were recurrent (2 EM, 1 arthritis). The annual incidence (0.8%) in this seropositive group was identical to the incidence observed among the whole population in 1986. The individual antibody titer decreased slightly but the seroreversion rate was low (7%). Serology was not very helpful in identifying clinical cases and evolutions, and it can be stated, that a positive serology is much more frequent in this risk group than clinical disease.


Subject(s)
Antibodies, Bacterial/blood , Borrelia burgdorferi Group/immunology , Immunoglobulin G/blood , Lyme Disease/epidemiology , Acrodermatitis/epidemiology , Adult , Aged , Arthritis, Infectious/epidemiology , Erythema Chronicum Migrans/epidemiology , Female , Follow-Up Studies , Humans , Incidence , Longitudinal Studies , Lyme Disease/immunology , Lyme Disease/pathology , Male , Middle Aged , Population Surveillance , Prevalence , Recurrence , Risk Factors , Seroepidemiologic Studies , Sports , Switzerland/epidemiology
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