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Open Forum Infect Dis
; 8(6): ofab209, 2021 Jun.
Article
in English
| MEDLINE
| ID: mdl-34113687
ABSTRACT
Cell cytotoxicity neutralization assay (CCNA) is considered to be a gold standard to diagnose Clostridioides difficile infections. We performed CCNA on 77 consecutive admission screening rectal swabs from asymptomatic toxigenic C. difficile carriers. Thirty-nine percent of specimens from asymptomatic carriers were positive. Thus, CCNA specificity may be lower than previously thought.