On the possibility of recording and studying human movement activity with seismic sensors of a new type: Advantages and prospects of the single-layer flat-coil-oscillator technology based sensors.

This paper presents main classes and varieties of sensors developed on the basis of the single-layer flat-coil-oscillator (SFCO) technology. The results of registration of human activity (steps and jumps) by seismic sensors based on this technology are presented and discussed in this paper. We applied some algorithms for digital processing of "RAW" data coming from vibrational seismic SFCO sensors, which made it possible to detect and mark out human steps and jumps from the background of natural ground vibrations. The unprecedented sensitivity of these sensors has been demonstrated, which, under favorable conditions (low natural ground vibrations), enables step-by-step registration of human activity at distances up to 350-370 m from the sensor installation point in the ground. The advantages of three-dimensional (3D) SFCO seismic sensors, which allow detecting human activity even with unfavorable environmental parameters and filtering features of the soil due to their anisotropy, have been demonstrated. The possibility of detecting soil features with new SFCO sensors is also shown. Possible applications of vibration seismic SFCO sensors in other areas are also discussed.

Serum Concentrations of Vascular Endothelial Growth Factor, Stromal Cell-Derived Factor, Nitric Oxide and Endothelial DNA Proliferation in Development of Microvascular Pathology in Acute African Swine Fever.

There is significant evidence that pathology of the microcirculation occurs in African swine fever (ASF); however, the mechanisms by which it develops are largely unknown. In the present experimental infection study, we show that an increase in vascular permeability in the initial stages of acute ASF is dependent on viraemia and elevation of the concentration of serum nitric oxide (NO). Macrophages activated by ASF virus (ASFV) are stimulated to produce NO and simultaneously to sensitize the endothelial cells through the action of vascular endothelial growth factor Β (VEGFΒ), which is followed by an increase in VEGF-mediated endothelial permeability. In the later stages of disease, the endothelial cells undergo DNA proliferation, which may additionally provoke capillary leakage, point haemorrhages and migration of blood cells into tissues. The possible mechanism of a shift in the cell cycle from the G1 to S and G2 stages could be a direct effect of ASFV. The terminal stages of disease are characterized by triggering of compensatory mechanisms such as stimulation of the synthesis of stromal cell-derived factor-1.