ABSTRACT
Objective: The objective of this study was to determine the diagnostic value of stress perfusion CMR for the detection of coronary artery disease. Methods: The was a retrospective cross sectional study in which 43 subjects were included from Cardiac MRI unit in the Hayatabad Medical Complex, Peshawar for study from 1st April 2020 to 30th November 2020. All the subjects who had been referred for stress perfusion CMR with suspected CAD were included in the study. Cardiac MRI both at rest and with adenosine stress perfusion was performed which was followed by invasive coronary angiography. Result: A total of 43 patients were enrolled for the detection or exclusion CAD who underwent stress perfusion CMRI and invasive coronary artery angiography. The study revealed strong and statistically significant association between positive stress perfusion CMR and positive coronary angiogram vs negative stress perfusion CMR and negative coronary angiogram (p= value 0.0001). Conclusions: Stress perfusion CMRI can be considered as a first line, relatively safe, noninvasive test with significant accuracy to diagnose coronary artery disease in patients with suspected CAD without subjecting these patients to invasive coronary angiogram.
ABSTRACT
UNLABELLED: Heart failure is a prevalent debilitating disease of poor prognosis in which heart cannot fill with or eject the sufficient amount of blood that is required due to structural or functional cardiac disorder. Depression is 4-5 times as common in heart failure (HF) patients as in the general population, and it might confer a higher risk of developing HF and negatively affect prognosis in established HF. OBJECTIVE: To determine the frequency of depression among patients presenting with chronic heart failure. METHODS: This descriptive cross sectional study was conducted in cardiology department Hayat Abad Medical Complex Peshawar from November 2011 to April 2012. In this study a total of 121 patients were observed by using 13% proportion of depression in heart failure, 95% confidence level and 6% margin of error, under WHO software for sample size determination. RESULTS: Mean age was 55 +/- 1.26 years. Sixty-eight percent patients were male and 32% were female. Fifteen percent patients had chronic heart failure for less than 1 year, 37% had chronic heart failure for 2-3 years and 48% patients had chronic heart failure for 3-4 years. Seventy percent patients had HADS score < 11 and 30% had HADS scored of > 11. Thirty percent patients had depression in chronic heart failure while 70% did not have depression in heart failure. CONCLUSION: Depression is common among CHF patients. Severe depression is more frequent than mild depression.
