ABSTRACT
INTRODUCTION: Primary laryngeal lymphomas are exceedingly rare. Only about a hundred cases have been reported. They consist mainly of non-Hodgkin lymphoma, especially of diffuse large B-cell lymphoma and mucosa-associated lymphoid tissue. We report the first case of a primary laryngeal mantle cell lymphoma. CASE PRESENTATION: We report a case of a primary mantle cell lymphoma of the larynx in a 70-year-old North African non-smoker male. We present a detailed report of his clinical and paraclinical data as well as treatment options. CONCLUSIONS: Mantle cell lymphoma is a very aggressive lymphoma subset associated with poor prognosis. Laryngeal mantle cell lymphoma is exceedingly rare. To the best of our knowledge, this is the first case to ever be reported.
ABSTRACT
BACKGROUND: Breast cancer is the most common cancer affecting women in Morocco. Screening for early detection has led to reduction in mortality from the disease. It is known that female healthcare professionals have greater influence on women's positive perception of breast cancer and motivation to practice screening methods for early detection of the disease. This study aims to investigate knowledge of breast cancer risk factors, beliefs about treatment and practice of screening methods among a cohort of female healthcare professionals in Morocco. METHODS: A cross-sectional study was conducted using a self-administered questionnaire to assess the knowledge of breast cancer risk factors, beliefs about treatment and practice of screening methods among 136 female doctors and nurses working in the university hospital of Rabat, Morocco. Stratified random sampling method was employed. Chi square test, analysis of variance and Mantel-Haenszel test were performed in data analysis using SPSS v19.0. RESULTS: Female doctors were the only professional group that had satisfactory knowledge of risk factors while the nurses had an unsatisfactory knowledge with a mean score of 43%. A half of participants believed that that herbal therapy can cure breast cancer. 75% practice breast self-examination once a month and only 15% have ever had a mammogram. Age, profession and beliefs were not significantly associated with rate of BSE in this study; however this rate is influenced by knowledge of breast cancer risk factors. CONCLUSION: Results from this study suggest the need for continuing medical education programs aimed at improving knowledge of breast cancer among the nurses.
Subject(s)
Attitude of Health Personnel , Breast Neoplasms , Health Knowledge, Attitudes, Practice , Practice Patterns, Nurses' , Practice Patterns, Physicians' , Adult , Breast Neoplasms/diagnosis , Breast Neoplasms/therapy , Cross-Sectional Studies , Female , Humans , Middle Aged , Morocco , Risk Factors , Young AdultSubject(s)
Adenocarcinoma/surgery , Esophageal Neoplasms/surgery , Esophagogastric Junction/surgery , Stomach Neoplasms/surgery , Adenocarcinoma/pathology , Adult , Aged , Aged, 80 and over , Esophageal Neoplasms/pathology , Esophagectomy/methods , Esophagogastric Junction/pathology , Female , Gastrectomy/methods , Hospitals, University , Humans , Male , Middle Aged , Morocco , Retrospective Studies , Stomach Neoplasms/pathology , Treatment Outcome , Young AdultABSTRACT
Introduction: L'incidence du cancer de la Jonction oesogastrique (JOG) ne cesse d'augmenter depuis les deux dernieres decades aussi bien dans les pays industrialises que dans les pays en voie dedeveloppement notamment le Maroc. Le rapprochement sur le plan etiopathogenique desadenocarcinomes (ADK) du cardia et ceux du bas oesophage reste un sujet de controverse posant leprobleme du choix therapeutique chirurgical; notamment l'etendu de la resection. Le but de ce travail est de dresser le profil epidemiologique des patients operes pour un ADK du cardia et analyser les gesteschirurgicaux realises par l'equipe chirurgicale A du centre hospitalier universitaire IBN SINA a Rabat atravers une serie de 149 cas. Methodes: Il s'agit d'une etude retrospective ayant interesse les malades operes pour un ADK de la JOG sur une periode de 15 annees (1990-2004) en chirurgie A du CHU IBNSINA a Rabat. Resultats: 149 cas d'ADK de la JOG ont ete retenus. L'age moyen etait de 55 ans; 76etaient de sexe masculin avec un sex-ratio de 3/1. Les signes cliniques les plus frequemment observessont la dysphagie (70); les douleurs epigastriques (67) et le reflux gastro-oesophagien (15.5). La notion de tabagisme n'a ete rapportee que chez 20des cas et l'oesophage de barret chez 10des patients. Le type I de Siewert a concerne 65 cas (43.5); le type II 40 cas (27); et le type III 44 cas (29.5). Dans le type I une oesophagectomie transhiatale a ete proposee; alors que les type II et III ont ete traite comme un cancer de l'estomac par une gastrectomie totale. Les suites operatoires etaient simples chez 80des patients; la mortalite globale etait de 8.5. Conclusion: L'oesophagectomie par voie transhiatale chez les patients fragiles avec un ADK de la JOG de type I permet des resultats carcinologiques satisfaisants avec reduction de la morbidite postoperatoire par rapport a la voie transthoracique. La gastrectomie totale est le traitement de choix pour les types III; alors que le debat est toujours ouvert quant a la meilleure strategie chirurgicale pour la prise en charge des tumeurs de type II
Subject(s)
Adenocarcinoma/surgery , Case Reports , Esophagogastric JunctionABSTRACT
Small cell carcinoma of the bladder (SCCB) is extremely rare. In this paper, we present a case of metastatic SCCB managed by chemotherapy and we would provide a brief review of the epidemiology, clinical features, diagnosis, pathologic features, staging, treatment, and prognosis of SCCB. A 52-year-old man was admitted with signs and symptoms suggestive of a bladder cancer. Computed tomography of the pelvis and abdomen showed a large tumor at the right bladder wall, measuring 10 cm in diameter, and a multinodular liver disease. Diagnosis of small cell carcinoma was established from the histological study of the transurethral resection of the bladder tumor. The patient received 12 cycles of platinum-based chemotherapy with a good partial response of bladder tumor and liver metastasis. The patient is still alive, 18 months after diagnosis.
